In vivo and in vitro antidiabetic potential of Taraxacum officinale root extracts

1. American Diabetes Association. Diagnosis and classification of diabetes mellitus. Diabetes Care. 2005;28:37-42.10.2337/diacare.28.suppl_1.S37Search in Google Scholar

2. Kavishankar GB, Lakshmidevi N, Murthy SM, Prakash HS, Niranjana SR. Diabetes and medicinal plants. A review. Int J Pharm Biomed Sci. 2011;2(3):65-80.Search in Google Scholar

3. Tom A, Philip SS, Mary GM, Menamin C, David AC. Streptozotocin diabetes, correlation with extent of depression of pancreatic islet nicotinamide adenine dinucleotide. J Clin Investig. 1974;54:672-7.10.1172/JCI107805Search in Google Scholar

4. Tailang M, Gupta BK, Sharma A. Antidiabetic activity of alcoholic extract of Cinnamomum zeylanicum leaves in alloxan-induced diabetic rats. People’s J Sci Res. 2008;1:9-11.Search in Google Scholar

5. Hui H, Tang G, Go VLW. Hypoglycemic herbs and their action mechanisms. Chin Med. 2009;4:11-4.10.1186/1749-8546-4-11Search in Google Scholar

6. Maurice AE. Some common locations of Dandelion in Africa. African handbooks; 2003.Search in Google Scholar

7. Robert F, Barnes C, Jerry N, Kenneth JM, Michael C. Forages volume 2: The science of grassland agriculture. Iowa: Wiley-Blackwell; 2007:11.Search in Google Scholar

8. Van Dijk PJ. Ecological and evolutionary opportunities of apomixes: Insights from Taraxacum and Chondrilla philosophical transactions of the Royal Society. Biol Scie. 2003;358(1434):1113.10.1098/rstb.2003.1302Search in Google Scholar

9. Schutz K, Carle R, Schieber A. Taraxacum – A review on its phytochemical and pharmacological profile. J Ethnopharmacol. 2006;107:313-23.10.1016/j.jep.2006.07.021Search in Google Scholar

10. Bensky D, Clavey S, Stoger E, Gamble A. Chinese Herbal Medicine: Materia Medica. 3rd ed. Seattle, WA: Eastland Press; 2004.Search in Google Scholar

11. Nnamdi CH, Uwakwe A, Chuku C. Hypoglycemic effects of aqueous and ethanolic extracts of dandelion (Taraxacum officinale F. H. Wigg.) leaves and roots on streptozotocin-induced albino rats. GJRMI. 2012;1(6):211-7.Search in Google Scholar

12. Grieve M. A Modern Herbal. New York: Dover Publications; 1931.Search in Google Scholar

13. Sweeney B, Vora M, Ulbricht C, Basch E. Evidence-based systematic review of dandelion (Taraxacum officinale) by natural standard research collaboration. J Herb Pharmacoth. 2005;5:79-93.10.1080/J157v05n01_09Search in Google Scholar

14. Clarke CB. Edible and useful plants of California. Berkeley: University of California Press; 1997:191.Search in Google Scholar

15. Yashpal PC. Chemical constituents of dandelion. Herbal Legacy 2004;12-14.10.1016/S0262-1762(04)00387-6Search in Google Scholar

16. Mona A, Yogesh A, Prakash I, Arun P, Jayshree V, Amruta K. Phytochemical and HPTLC studies of various extracts of Annona squamosa (Annonaceae). Int J Pharmtech Res. 2012;4(1):364-8.Search in Google Scholar

17. Siriangkhawut W, Kaewboo I. Ultrasonic extraction method for alizarin from roots of Morinda citrifolia. ACAIJ. 2013;12(2);65-9.Search in Google Scholar

18. Organization for Economic Cooperation and Development (OECD). (Test No. 423), Guideline for testing of chemicals acute oral toxicity – acute toxic class method. 2001. Available at: http://www.oecd.org/chemicalsafety/riskassessment/1948370.pdf. Accessed 15.07.15.Search in Google Scholar

19. Khalid A, Kuong YM, Item JA, Mohd ZA, Amirin S, Vikneswaran M, et al. Hypoglycemic and anti-hyperglycemic study of Gynura procumbens leaf extracts. Asian Pac J Trop Biomed. 2013;3(5):358-66.10.1016/S2221-1691(13)60077-5Search in Google Scholar

20. O’Brien J, Wilson I, Orton T, Pognan F. Investigation of the Alamar Blue (resazurin) fluorescent dye for the assessment of mammalian cell cytotoxicity. Eur J Biochem. 2000;267:5421-6.10.1046/j.1432-1327.2000.01606.x10951200Search in Google Scholar

21. Kuete V, Mbaveng AT, Nono EC, Simo CC, Zeino M, Nkengfack AE, et al. Cytotoxicity of seven naturally occurring phenolic compounds towards multi-factorial drug-resistant cancer cells. Phytomedicine. 2016;23:856-63.10.1016/j.phymed.2016.04.00727288921Search in Google Scholar

22. Zou C, Wang Y, Shen Z. 2-NBDG as a f luorescent indicator for direct glucose uptake measurement. J Bioch Bioph Method. 2005;64(3):207-15.10.1016/j.jbbm.2005.08.001Search in Google Scholar

23. Slinkard K, Singleton VL. Total phenol analyses: automation and comparison with manual methods. Am J Enology Vitic. 1977;28:49-55.10.5344/ajev.1974.28.1.49Search in Google Scholar

24. Moreno MIN, Isla MI, Sampietro AR, Vattuone MA. Comparison of the free radical-scavenging activity of propolis from several regions of Argentina. J Ethnopharmacol. 2000;71:109-14.10.1016/S0378-8741(99)00189-0Search in Google Scholar

25. Akdeniz M. Screening of Chemical Content Specific to Hyperıcum Species Growing in Different Parts of Turkey by LC-MS/MS and Method Validation; Investigation of Their Biological Activities and Chemometric Evaluation. Dicle University Institute of Science Department of Chemistry, Ph.D. Thesis, Diyarbakır; 2018.Search in Google Scholar

26. Khan CR, Shechter Y. In: W. R. Theodore, S. N. Alan, P. Taylor, A. G. Gilman, editors. Goodman and Gilman’s The Pharmacological Basis of Therapeutics, 8th ed. Oral hypoglycemic agents and the pharmacology of the endocrine pancreas. New York: McGraw-Hill; 1991.Search in Google Scholar

27. Wanniarachchi KK, Peiris LDC, Ratnasooriya WD. Antihyperglycemic and hypoglycemic activities of Phyllanthus debilis aqueous plant extract in mice. Pharm Biol. 2009;47:260-5.10.1080/13880200802435754Search in Google Scholar

28. Rangika BS, Dayananda PD, Peiris DC. Hypoglycemic and hypolipidemic activities of aqueous extract of flowers from Nyctanthes arbor-tristis L. in male mice. BMC Complement Altern M. 2015;15:1-9.Search in Google Scholar

29. Foretz M, Viollet B. Regulation of hepatic metabolism by AMPK. Hepatology. 2011;54 (4): 827-9.10.1016/j.jhep.2010.09.01421163246Search in Google Scholar

30. Viollet B, Guigas B, Sanz Garcia N, Leclerc J, Foretz M, Andreelli F. Cellular and molecular mechanisms of metformin: an overview. Clin Sci. 2012;122 (6):253-70.10.1042/CS20110386339886222117616Search in Google Scholar

31. Iddrisu I, Oduro I, Aferiba M, Reginald T, Annan A. Anti-diabetic effect of dandelion leaves and roots in type two diabetic patients. NFS. 2015;45(3):479-92.10.1108/NFS-01-2015-0001Search in Google Scholar

32. Jinchun Z and Jie C. The effects of Taraxacum officinale extracts (toe) supplementation on physical fatigue in mice. AJTCAM. 2011;8(2):128-33.10.4314/ajtcam.v8i2.63198325269022238492Search in Google Scholar

33. Nnamdi CC, Uwakwe A, Chuku L. Effect of aqueous and ethanolic extracts of dandelion (Taraxacum officinale F. H. Wigg.) leaves and roots on some hematological parameters of normal and STP-induced diabetic Wistar albino rats. Glob R Res Med Plants Indig Med. 2012a;1(5):172-80.Search in Google Scholar

34. Song Y, Manson JE, Buring JE, Sesso HD, Liu S. Associations of Dietary Flavonoids with Risk of Type 2 Diabetes, and Markers of Insulin Resistance and Systemic Inflammation in Women: A Prospective Study and Cross-Sectional Analysis. J Am Coll. Nutr. 2005;24:376-84.Search in Google Scholar

35. Tadera K, Minami Y, Takamatsu K, Matsuoka T. Inhibition of α-glucosidase and α-amylase by flavonoids. J Nutr Sci Vitaminol. 2006;52:149-53.10.3177/jnsv.52.14916802696Search in Google Scholar

36. Lu Z, Jia Q, Wang R, Wu X, Wu Y, Huang C, et al. Hypoglycemic activities of A- and B-type procyanidin oligomer-rich extracts from different Cinnamon barks. Phytomedicine. 2011;18(4):298-302.10.1016/j.phymed.2010.08.00820851586Search in Google Scholar

37. Kenny O, Smyth TJ, Hewage CM, Brunton NP. Antioxidant properties and quantitative UPLC-MS/MS analysis of phenolic compounds in dandelion (Taraxacum officinale) root extracts. Free Radicals Antioxidants. 2014;4(1):55-61.10.5530/fra.2014.1.9Search in Google Scholar

38. Karthikesan K, Pari L, Menon VP. Antihyperlipidemic effect of chlorogenic acid and tetrahydrocurcumin in rats subjected to diabetogenic agents. Chem Biol Interact. 2010;188(3):643-50.10.1016/j.cbi.2010.07.02620696151Search in Google Scholar

39. Shengxi M, Jianmei C, Qin F, Jinghua P, Yiyang H. Roles of Chlorogenic Acid on Regulating Glucose and Lipids Metabolism: A Review. Evid Based Complementary Altern Med. 2013;11:Article ID 801457.10.1155/2013/801457376698524062792Search in Google Scholar

40. Harini R, Pugalendi KV. Antihyperglycemic effect of protocatechuic acid on streptozotocin-diabetic rats. J Basic Clin Physiol Pharmacol. 2011;21(1):79-91.Search in Google Scholar

41. Hui H, Tang G, Go VLW. Hypoglycemic herbs and their action mechanisms. Chin Med. 2009;4:11-4.10.1186/1749-8546-4-11270421719523223Search in Google Scholar

42. Yanqing Z, Kiharu I, Yu L. Anti-diabetic effects of luteolin and luteolin-7-O-glucoside on KK-Ay mice. Biosci Biotechnol Biochem. 2016;80(8):1580-6.10.1080/09168451.2015.111692827170065Search in Google Scholar

43. Hu C, Kitts DD. Dandelion (Taraxacum officinale) flower extract suppresses both reactive oxygen species and nitric oxide and prevents lipid oxidation in vitro. Phytomedicine. 2005;12(8):588-97.10.1016/j.phymed.2003.12.01216121519Search in Google Scholar

44. Boden G. Role of fatty acids in the pathogenesis of insulin resistance and NIDDM. Diabetes. 1997;46(1):3-10.10.2337/diab.46.1.3Search in Google Scholar

45. Li X, Wang X, Chen D, Chen S. Antioxidant Activity and Mechanism of Protocatechuic Acid in vitro. Funct Food Health Dis. 2011;1(7):332-44.10.31989/ffhd.v1i7.127Search in Google Scholar