Evaluation of interleukin-6 concentration in the liver of Albino Swiss mice after intoxication with various doses of patulin

1. Puel O, Galtier P, Oswald IP. Biosynthesis and Toxicological Effects of Patulin. Toxins. 2010;2(4):613-31.10.3390/toxins2040613315320422069602Search in Google Scholar

2. Bennet JW, Klich M. Mycotoxins. Clin Microbiol Rev. 2003;16(3):497-516.10.1128/CMR.16.3.497-516.200316422012857779Search in Google Scholar

3. Chełkowski J. Mikotoksyny, grzyby toksynotwórcze i mikotoksykozy. http://www.cropnet.pl/dbases/mycotoxins.pdf.pl/download. 2010, [accessed 2010 June 20].Search in Google Scholar

4. Wilson DM, Mubatanhema W, Jurjevic Z. Biology and ecology of mycotoxigenic Aspergillus species as related to economic and health concerns. Adv Exp Med Biol. 2002;504:1-17.10.1007/978-1-4615-0629-4_211922097Search in Google Scholar

5. Balas J. Mikotoksyny jako źródło zanieczyszczeń żywności pochodzenia roślinnego. Postępy Fitoterapii. 2006;2:98-104.Search in Google Scholar

6. Grajewski J. Mikotoksyny i grzyby pleśniowe. Zagrożenie dla człowieka i zwierząt. Bydgoszcz. Wyd. UKW, 2006.Search in Google Scholar

7. Jarzynka S, Dąbkowska M, Netsvyetayeva I, Swoboda-Kopeć E. Mikotoksyny – niebezpieczne metabolity grzybów pleśniowych. Medycyna Rodzinna. 2010;4:113-9.Search in Google Scholar

8. Santini A, Raiola A, Meca G, Ritieni A. Aflatoxins, Ochratoxins, Trichotecenes, Patulin, Fumonisins and Beauvericin in Finished Products for Human Consumption. J Clin Toxicol. 2015;5(4):2-11.Search in Google Scholar

9. Szymczyk K, Szteke B, Goszcz H. Występowanie patuliny w krajowych sokach jabłkowych. Roczn PZH. 2004;55(3):255-60.Search in Google Scholar

10. Kurpińska-Jaworska J, Ledzion E, Szczęsna M, Karłowski K, Postupolski J, Rybińska K. Nowe przepisy Unii Europejskiej w zakresie patuliny. Roczn PZH. 2003;54(4): 355-61.Search in Google Scholar

11. Rozporządzenie Komisji Wspólnoty Europejskiej NR 1881/2006 z dnia 19 grudnia 2006 r. ustalające najwyższe dopuszczalne poziomy niektórych zanieczyszczeń w środkach spożywczych. L364 5-24.Search in Google Scholar

12. Wróbel B. Zagrożenia zwierząt i ludzi toksynami grzybów pleśniowych zawartych w paszach i żywności. Woda-Środowisko-Obszary Wiejskie. 2014;14:159-76.Search in Google Scholar

13. Al-Hazmi MA. Patulin in apple juice and its risk assessments on albino mice. Toxicol Ind Health. 2014;30(6):534-45.10.1177/074823371245745423012343Search in Google Scholar

14. Arzu Koçkaya E, Selmanoğlu G, Ozsoy N, Gül N. Evaluation of patulin toxicity in the thymus of growing male rats. Arh Hig Rada Toksikol. 2009;60:411-8.10.2478/10004-1254-60-2009-197320061241Search in Google Scholar

15. Bouhet S, Oswald IP. The effects of mycotoxins, fungal food contaminants, on the intestinal epithelial cell-derived innate immune response. Vet Immunol Immunopathol. 2005;108:199-209.10.1016/j.vetimm.2005.08.01016144716Search in Google Scholar

16. Glaser N, Stopper H. Patulin: Mechanism of genotoxicity. Food Chem Toxicol. 2012;50(5):1796-801.10.1016/j.fct.2012.02.09622425938Search in Google Scholar

17. Grajewski J, Twarużek M. Zdrowotne aspekty oddziaływania grzybów pleśniowych i mikotoksyn. Alergia. 2004;3:45-9.Search in Google Scholar

18. Ozsoy N, Selmanoğlu G, Koçkaya EA, Gül N, Cebesoy S. Effect of patulin on the interdigitating dendritic cells (IDCs) of rat thymus. Cell Biochem Funct. 2008;26(2):192-6.10.1002/cbf.143117702051Search in Google Scholar

19. Pfeiffer E, Diwald TT, Metzler M. Patulin reduces glutathione level and enzyme activities in rat liver slices. Mol Nutr Food Res. 2005;49(4):329-36.10.1002/mnfr.20040008915744717Search in Google Scholar

20. Roll R, Matthiaschk G, Korte A. Embryotoxicity and mutagenicity of mycotoxins. J Environ Pathol Toxicol Oncol. 1990;10:1-7.Search in Google Scholar

21. Mahfoud R, Maresca M, Garmy N, Fantini J. The mycotoxin patulin alters the barrier function of the intestinal epithelium: mechanism of action of the toxin and protective effects of glutathione. Toxicol Appl Pharmacol. 2002;15,181(3):209-18.Search in Google Scholar

22. Maresca M, Yahi N, Younès-Sakr L, Boyron M, Caporiccio B, Fantini J. Both direct and indirect effects account for the pro-inflammatory activity of enteropathogenic mycotoxins on the human intestinal epithelium: Stimulation of interleukin-8 secretion, potentiation of interleukin-1beta effect and increase in the transepithelial passage of commensal bacteria. Toxicol Appl Pharmacol. 2008;228:84-92.10.1016/j.taap.2007.11.01318308354Search in Google Scholar

23. Nagasue N, Yukaya H, Ogawa Y, Kohno H, Nakamura T. Human liver regeneration after major hepatic resection. A study of normal liver and livers with chronic hepatitis and cirrhosis. Ann Surg. 1997;206:30-9.10.1097/00000658-198707000-00005Search in Google Scholar

24. Nagwa M, El-Sawi NM, Gashlan HM, Younes SH, Al-Massabi RF, Shaker S. Biochemical and histological studies on the effect of the Patulin mycotoxin on male rats’ liver and treatment by crude venom extracted from jelly fish. Life Sci J. 2012;9(4):1143-53.Search in Google Scholar

25. Song E, Xia X, Su C, Dong W, Xian Y, Wang W, et al. Hepatotoxicity and genotoxicity of patulin in mice, and its modulation by green tea polyphenols administration. Food Chem Toxicol. 2014;71:122-7.10.1016/j.fct.2014.06.009Search in Google Scholar

26. Scheller J, Ohnesorge N, Rose-John S. Interleukin-6 trans-signalling in chronic inflammation and cancer. Scand J Immunol. 2006;63:321-9.10.1111/j.1365-3083.2006.01750.x16640655Search in Google Scholar

27. Wichmann G, Herbarth O, Lehmann I. The mycotoxins citrinin, gliotoxin, and patulin affect interferon-gamma rather than interleukin-4 production in human blood cells. Environ Toxicol. 2002;17:211-8.10.1002/tox.10050Search in Google Scholar

28. Seidelin JB, Bjerrum JT, Coskun M, Widjaya B, Vainer B, Nielsen OH. IL-33 is upregulated in colonocytes of ulcerative colitis. Immunol. Lett. 2010;128:80-5.Search in Google Scholar

29. Gabay C. Interleukin-6 and chronic inflammation. Arthritis Res. Ther. 2006:8(2):2-8.10.1186/ar1917Search in Google Scholar

30. Gaini S, Koldkjaer OG, Pedersen C. Procalcitonin, lipopolysaccharide-binding protein, interleukin-6 and C-reactive protein in community-acquired infections and sepsis: a prospective study. Crit Care. 2006:10:53.Search in Google Scholar

31. Ishihara K, Hirano T. IL-6 in autoimmune disease and chronic inflammatory proliferative disease. Cytokine Growth Factor Rev. 2002;13:357-68.10.1016/S1359-6101(02)00027-8Search in Google Scholar

32. Kishimoto T. IL-6: from its discovery to clinical applications. Int Immunol. 2010;22(5):347-52.10.1093/intimm/dxq03020410258Search in Google Scholar

33. Scheller J, Ohnesorge N, Rose-John S. Interleukin-6 trans-signalling in chronic inflammation and cancer. Scand J Immunol. 2006;63:321-9.10.1111/j.1365-3083.2006.01750.xSearch in Google Scholar

34. Bondy GS, Pestka JJ. Immunomodulation by fungal toxins. J Toxicol Environ Health. 2000;3(2):109-43.10.1080/10937400028111310834078Search in Google Scholar

35. Dziennik Urzędowy Unii Europejskiej. L50/8 z 27.02.2010.Search in Google Scholar

36. Gashlan HM. Biochemical Studies of Patulin on Liver Functions in Male Albino Mice. J Apple Anim Res. 2008;34(1):93-6.10.1080/09712119.2008.9706947Search in Google Scholar

37. Walusia J, Gutarowska B, Żakowska Z, Pałczyński C. Grzyby Pleśniowe w środowisku komunalnym i w miejscu pracy – istotne zagrożenie zdrowotne. Medycyna Pracy. 2004;55(3):257-66.Search in Google Scholar

38. Luft P, Oostingh GJ, Gruijthuijsen Y, Horejs-HoeckJ, Lehmann I, Duschl A. Patulin Influences the Expression of Th1/Th2 Cytokines by Activated Peripheral Blood Mononuclear Cells and T Cells Through Depletion of Intracellular Glutathione. Environ Toxicol. 2008;23:84-95.10.1002/tox.20309Search in Google Scholar

39. Puel O, Tadrist S, Delaforge M, Oswald IP, Lebrihi A. The inability of Byssochlamys fulva to produce patulin is related to absence of 6-methylsalicylic acid synthase and isoepoxydon dehydrogenase genes. Int J Food Microbiol. 2007;115:131-9.10.1016/j.ijfoodmicro.2006.10.016Search in Google Scholar

40. Gabay C. Interleukin-6 and chronic inflammation. Arthritis Res. Ther. 2006;8(2):2-8.Search in Google Scholar

41. Ishihara K, Hirano T. IL-6 in autoimmune disease and chronic inflammatory proliferative disease. Cytokine Growth Factor Rev. 2002;13:357-68.10.1016/S1359-6101(02)00027-8Search in Google Scholar

42. Urbanowicz W. Rola wątroby w odpowiedzi ostrej fazy. Postępy Nauk Medycznych. 2000;1:46-9.Search in Google Scholar

43. Andrews NC. Anemia of inflammation: the cytokine-hepcidin link. J Clin Invest. 2004;113:1251-3.10.1172/JCI2144139843515124013Search in Google Scholar

44. Koczy-Baron E, Kasperska-Zając A. Rola naczyniowo-śródbłonkowego czynnika wzrostu w procesach zapalnych. Postępy Hig Med Dośw. 2014;68:57-65.10.5604/17322693.108636024491896Search in Google Scholar

45. Zhang Y, Matsuo H, Morita E. Increased production of vascular endothelial growth factor in the lesions of atopic dermatitis. Arch Dermatol Res. 2006;297:425-9.10.1007/s00403-006-0641-916456664Search in Google Scholar