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<p> The influence of docosahexaenoic (DHA) acid obtained from a new generation of eggs on ventricular electrical function of 24 pigs with experimentally induced tachycardiomyopathy was described. Two groups were formed, 12 pigs had experimentally evoked tachycardiomyopathy and were getting standard feed (control group TIC). Twelve pigs with tachycardiomyopathy received feed with an addition of a dietary supplement containing phospholipids isolated from new generation of eggs at a dose of 1,000 mg of DHA/animal/24 h (experimental group TIC). Electrophysiological study was carried out from an external programmer immediately after implantation of the pacemaker. All the tests were carried out in general anaesthesia. After 8 weeks of fast ventricular pacing at 170 bpm in pigs receiving phospholipids obtained from eggs, a statistically significant shortening of ventricular refraction time was observed during sinus rhythm and also during the ventricular pacing of 130 bpm, and 150 bpm in the group of pigs fed standard feed. The ventricular refraction time in the sinus rhythm was significantly longer after 12 weeks of fast pacing and in the pacing at 130 bpm and 150 bpm it was significantly longer after 8 weeks of fast pacing. Phospholipids containing high percentage of n-3 polyunsaturated fatty acids (PUFA) obtained from new generation of eggs may contribute to the shortening ventricular refraction period after its oral administration. The n-3 PUFA obtained from a new generation of hen eggs may be an alternative to fish oil source of DHA and other polyunsaturated fatty acids.</p>
</abstract>

The influence of docosahexaenoic (DHA) acid obtained from a new generation of eggs on ventricular electrical function of 24 pigs with experimentally induced tachycardiomyopathy was described. Two groups were formed, 12 pigs had experimentally evoked tachycardiomyopathy and were getting standard feed (control group TIC). Twelve pigs with tachycardiomyopathy received feed with an addition of a dietary supplement containing phospholipids isolated from new generation of eggs at a dose of 1,000 mg of DHA/animal/24 h (experimental group TIC). Electrophysiological study was carried out from an external programmer immediately after implantation of the pacemaker. All the tests were carried out in general anaesthesia. After 8 weeks of fast ventricular pacing at 170 bpm in pigs receiving phospholipids obtained from eggs, a statistically significant shortening of ventricular refraction time was observed during sinus rhythm and also during the ventricular pacing of 130 bpm, and 150 bpm in the group of pigs fed standard feed. The ventricular refraction time in the sinus rhythm was significantly longer after 12 weeks of fast pacing and in the pacing at 130 bpm and 150 bpm it was significantly longer after 8 weeks of fast pacing. Phospholipids containing high percentage of n-3 polyunsaturated fatty acids (PUFA) obtained from new generation of eggs may contribute to the shortening ventricular refraction period after its oral administration. The n-3 PUFA obtained from a new generation of hen eggs may be an alternative to fish oil source of DHA and other polyunsaturated fatty acids.

Influence of Docosahexaenoic Acid Obtained from New Generation of Eggs on the Repolarisation of Ventricles in Pigs with Experimental Tachycardiomyopathy

Department of Internal Diseases with Horse, Dog and Cat Clinic Faculty of Life Sciences and Technology

Wroclaw University of Environmental and Life Sciences

Department and Clinic of Surgery, Faculty of Veterinary Medicine

Department of Animal Products Technology and Quality Management, Faculty of Life Sciences and Technology

Journal of Veterinary Research

The influence of docosahexaenoic (DHA) acid obtained from a new generation of eggs on ventricular electrical function of 24 pigs with experimentally induced...

Influence of Docosahexaenoic Acid Obtained from New Generation of Eggs on the Repolarisation of Ventricles in Pigs with Experimental Tachycardiomyopathy

Published Online: Jun 21, 2013

Page range: 269 - 274

DOI: https://doi.org/10.2478/bvip-2013-0047

This content is open access.