<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Deep caries progress is associated with tertiary dentin formation and additional reversible or irreversible dental pulp inflammation. It seems that some particular signs of pain in irreversible pulpitis are associated to a particular caries microflora. Streptococcus species, Parvimonas micra and Dialister invisus are prevailing in cases of throbbing pain while Streptococcus mutans is incriminated in sensitivity to vertical percussion of tooth. Continuous pain is thought to be the clinical outcome of Lactobacillus implication. A better understanding of molecular signals and mechanisms induced by microbiome of deep caries that orchestrate the modulation of dental pulp complex response toward tertiary dentinogenesis or pulp inflammation it is supposed to improve diagnosis and conservative therapies of vital pulp.</p></abstract>

Deep caries progress is associated with tertiary dentin formation and additional reversible or irreversible dental pulp inflammation. It seems that some particular signs of pain in irreversible pulpitis are associated to a particular caries microflora. Streptococcus species, Parvimonas micra and Dialister invisus are prevailing in cases of throbbing pain while Streptococcus mutans is incriminated in sensitivity to vertical percussion of tooth. Continuous pain is thought to be the clinical outcome of Lactobacillus implication. A better understanding of molecular signals and mechanisms induced by microbiome of deep caries that orchestrate the modulation of dental pulp complex response toward tertiary dentinogenesis or pulp inflammation it is supposed to improve diagnosis and conservative therapies of vital pulp.

Molecular Mechanisms of Dentine-Pulp Complex Response Induced by Microbiome of Deep Caries

Department of Oral Rehabilitation, Faculty of Dental Medicine

Department of Endodontics, Faculty of Dental Medicine

Department of Restorative Odontotherapy, Faculty of Dental Medicine

Department of Obstetrics and Gynecology, Faculty of Medicine

Department of Odontology, Faculty of Dental Medicine

ARS Medica Tomitana

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Deep caries progress is associated with tertiary dentin formation and additional reversible or irreversible dental pulp inflammation. It seems that some...

Molecular Mechanisms of Dentine-Pulp Complex Response Induced by Microbiome of Deep Caries

Published Online: Dec 11, 2019

Page range: 53 - 60

DOI: https://doi.org/10.2478/arsm-2019-0012

Keywords
deep caries, microbiome, tertiary dentine, molecular signals

© 2018 Iliescu Alexandru-Andrei et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Molecular Mechanisms of Dentine-Pulp Complex Response Induced by Microbiome of Deep Caries

Published Online: Dec 11, 2019

Page range: 53 - 60

DOI: https://doi.org/10.2478/arsm-2019-0012

Keywordsdeep caries, microbiome, tertiary dentine, molecular signals

© 2018 Iliescu Alexandru-Andrei et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
deep caries, microbiome, tertiary dentine, molecular signals