<abstract xmlns="http://www.w3.org/1999/xhtml"><p>The dentine-pulp complex response in deep caries is histological characterized by tertiary formation and mild chronic pulp inflammation. The quiescent primary odontoblasts are reactivated, laying down reactionary tertiary dentine. In more severe carious damage the primary odontoblasts die and reparative tertiary dentine is secreted by odontoblast-like cells, which are differentiated in adult teeth mainly from dental pulp stem cells DPSC. Though associated with reversible pulpitis DPSC still preserve in deep caries the capability of migration, proliferation and differentiation. Some common mechanisms of molecular signals involved in tertiary dentine formation might also explain the balance between inflammation and regeneration of dentine-pulp complex.</p></abstract>

The dentine-pulp complex response in deep caries is histological characterized by tertiary formation and mild chronic pulp inflammation. The quiescent primary odontoblasts are reactivated, laying down reactionary tertiary dentine. In more severe carious damage the primary odontoblasts die and reparative tertiary dentine is secreted by odontoblast-like cells, which are differentiated in adult teeth mainly from dental pulp stem cells DPSC. Though associated with reversible pulpitis DPSC still preserve in deep caries the capability of migration, proliferation and differentiation. Some common mechanisms of molecular signals involved in tertiary dentine formation might also explain the balance between inflammation and regeneration of dentine-pulp complex.

Reactionary Versus Reparative Dentine in Deep Caries

Department of Oral Rehabilitation, Faculty of Dental Medicine

Department of Restorative Odontotherapy, Faculty of Dental Medicine

Department of Oral Implantology, Faculty of Dental Medicine

Department of Endodontics, Faculty of Dental Medicine

Department of Obstetrics and Gynecology, Faculty of Medicine

ARS Medica Tomitana

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"Reactionary Versus Reparative Dentine in Deep Caries"}

The dentine-pulp complex response in deep caries is histological characterized by tertiary formation and mild chronic pulp inflammation. The quiescent primary...

Reactionary Versus Reparative Dentine in Deep Caries

Published Online: Aug 17, 2019

Page range: 15 - 21

DOI: https://doi.org/10.2478/arsm-2019-0004

Keywords
deep caries, reactionary dentine, reparative dentine

© 2019 Iliescu Alexandru-Andrei et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Reactionary Versus Reparative Dentine in Deep Caries

Published Online: Aug 17, 2019

Page range: 15 - 21

DOI: https://doi.org/10.2478/arsm-2019-0004

Keywordsdeep caries, reactionary dentine, reparative dentine

© 2019 Iliescu Alexandru-Andrei et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
deep caries, reactionary dentine, reparative dentine