Immunohistochemical study of Aquaporin-1, Cyclooxygenase-2 and Apoptosis Protease-Activating Factor-1 expression in breast cancers. Preliminary study

1. Blows, F.M., Driver, K.E., Schmidt, M.K., Broeks, A. & van Leeuwen, F.E. et al. (2010). Subtyping of Breast Cancer by Immunohistochemistry to Investigate a Relationship between Subtype and Short and Long Term Survival: A Collaborative Analysis of Data for 10,159 Cases from 12 Studies. PLoS Med. 7(5), e1000279. DOI:10.1371/journal.pmed.100027910.1371/journal.pmed.1000279287611920520800Search in Google Scholar

2. Otterbach, F., Callies, R., Adamzik, M., Kimmig, R., Siffert, W. & Schmid, K.W. et al. (2010). Aquaporin 1 (AQP1) expression is a novel characteristic feature of a particularly aggressive subgroup of basal-like breast carcinomas. BreastCancer Res Treat. 120(1), 67-7610.1007/s10549-009-0370-919306058Search in Google Scholar

3. Hu, J. & Verkman, A.S. (2006). Increased migration and metastatic potential of tumor cells expressing aquaporin water channels. FASEB J. 20(11), 1892-410.1096/fj.06-5930fje16818469Search in Google Scholar

4. van Nes, J.G., de Kruijf, E.M., Faratian, D., van de Velde, C.J., Putter, H. & Falconer, C. et al. (2011). COX2 expression in prognosis and in prediction to endocrine therapy in early breast cancer patients. Breast Cancer Res Treat. 125(3), 671-85Search in Google Scholar

5. Rolland, P.H., Martin, P.M. & Jacquemier, J. et al. (1980). Prostaglandin in human breast cancer: evidence suggesting that an elevated prostaglandin production is a marker of high metastatic potential for neoplastic cells. J NatlCancer Inst. 64, 1061-1070Search in Google Scholar

6. Khuder, S.A. & Mutgi, A.B. (2001). Breast cancer and NSAID use: a meta-analysis. Br JCancer. 84, 1188-119210.1054/bjoc.2000.1709236387911336469Search in Google Scholar

7. Campioni, M., Santini, D., Tonini, G., Murace, R., Dragonetti, E. & Spugnini, E.P. et al. (2005). Role of Apaf-1, a key regulator of apoptosis, in melanoma progression and chemoresistance. Exp Dermatol. 14, 811-81810.1111/j.1600-0625.2005.00360.x16232302Search in Google Scholar

8. Zlobec, I., Minoo, P., Baker, K., Haegert, D., Khetani, K. & Tornillo, L. et al. (2007). Loss of APAF-1 expression is associated with tumor progression and adverse prognosis in colorectal cancer. Eur J Cancer. 43(6), 1101-710.1016/j.ejca.2007.01.02917350821Search in Google Scholar

9. Osborne, C.K. (1998). Steroid hormone receptors in breast cancer management. Breast Cancer ResTreat. 51(3), 227-3810.1023/A:1006132427948Search in Google Scholar

10. Henderson, I.C. & Patek, A.J. (1998). The relationship between prognostic and predictive factors in the management of breast cancer. Breast Cancer Res Treat. 52(1-3), 261-8810.1023/A:1006141703224Search in Google Scholar

11. Nico, B. & Ribatti, D. (2010). Aquaporins in tumor growth and angiogenesis. Cancer Lett. 294(2), 135-810.1016/j.canlet.2010.02.00520199845Search in Google Scholar

12. Takeshita, E., Osanai, T., Higuchi, T., Soumaoro, L.T. & Sugihara, K. (2005). Elevated cyclooxygenase-2 expression is associated with histological grade in invasive ductal breast carcinoma. J Med Dent Sci. 52(4), 189-93Search in Google Scholar

13. Nassar, A., Radhakrishnan, A., Cabrero, I.A., Cotsonis, G. & Cohen, C. (2007). COX-2 expression in invasive breast cancer: correlation with prognostic parameters and outcome. ApplImmunohistochem Mol Morphol. 15(3), 255-910.1097/01.pai.0000213130.63417.b317721268Search in Google Scholar

14. Watanabe, O., Shimizu, T., Imamura, H., Kinoshita, J., Utada, Y. & Okabe, T. et al. (2003). Expression of cyclooxygenase-2 in malignant and benign breast tumors. Anticancer Res. 23(4), 3215-21Search in Google Scholar

15. Soengas, M.S., Capodieci, P., Polsky, D., Mora, J., Esteller, M. & Opitz-Araya, X. et al. (2001). Inactivation of the apoptosis effector Apaf-1 in malignant melanoma. Nature. 409(6817), 207-1110.1038/3505160611196646Search in Google Scholar

16. Jia, L., Srinivasula, S.M., Liu, F.T., Newland, A.C., Fernandes-Alnemri, T. & Alnemri E.S. et al. (2001). Apaf-1 protein deficiency confers resistance to cytochrome c-dependent apoptosis in human leukemic cells. Blood. 98(2), 414-2110.1182/blood.V98.2.414Search in Google Scholar

17. Wolf, B.B., Schuler, M., Li, W., Eggers-Sedlet, B., Lee, W. & Tailor, P. et al. (2001). Defective cytochrome c-dependent caspase activation in ovarian cancer cell lines due to diminished or absent apoptotic protease activating factor-1 activity. J Biol Chem. 276(36), 34244-5110.1074/jbc.M01177820011429402Search in Google Scholar

18. Leo, C., Richter, C., Horn, L.C., Schütz, A., Pilch, H. & Höckel, M. (2005). Expression of Apaf-1 in cervical cancer correlates with lymph node metastasis but not with intratumoral hypoxia. Gynecol Oncol. 97(2), 602-610.1016/j.ygyno.2005.01.04415863166Search in Google Scholar