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An actinobacterial strain named LG10 was isolated from a Saharan Atlas soil (Laghouat, Algeria). The aerial hyphae were yellowish-white on all culture media with rectiflexibiles spore chains, suggested that this bacterium attached to Streptomyces. Furthermore, LG10 contained chemical characteristics that were diagnostic for the genus Streptomyces, such as the presence of LL-diaminopimelic acid isomer (LL-DAP) and glycine amino acid. The hydrolysates of whole-cell included non-characteristic sugars. Comparative analysis of the 16S rDNA sequence displayed a similarity level of 100% with Streptomyces puniceus NRRL ISP-5058T. The antimicrobial activity of the LG10 strain was better in the culture medium MB5. Streptomyces strains are good sources of bioactive compounds with multiple biological activities.

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