This study was carried out to determine the effect of dietary supplementation of Dennettia tripetala on some biochemical parameters of rats. Twenty-five rats were used and were divided in to five groups of 5 rats. Group 1 served as control while group 2-5 were fed dietary inclusion of Dennettia tripetala fruits for 28 days. After the feeding trials, the rats were sacrificed and blood was collected for biochemical analyses. The serum concentration triglyceride and glucose were significantly lowered (p<0.05) while total protein, catalase and high-density lipoprotein were significantly higher (p<0.05) in rats fed with the formulated diet. There was no significant difference (p<0.05) in the serum level of superoxide dismutase, albumin, cholesterol and low-density lipoprotein of rats fed with the formulated diet. In conclusion, the study has shown that dietary inclusion of Dennettia tripetala fruits has hypoglycaemic, antioxidant and hypolipidemic effect. Therefore, it may help in the prevention of coronary heart disease, diabetes mellitus and cancer.
