<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Pesticides are designed to kill a very wide range of undesirable organisms, but they simultaneously adversely affect non-target organisms in ecosystems. Dimethoate is an organophosphorous insecticide used widely in agriculture that has an anticholinesterase mode of action. The goal of the study was to assess the effects of dimethoate on catalase, reduced glutathione, and lipid peroxidation in the gills and livers of zebrafish, <italic>Danio rerio</italic> (Hamilton), exposed to different concentrations of the pesticide for different periods of time. Insecticidal stress caused a reduction in catalase activity and reduced glutathione levels in zebrafish gills and livers. There was also increased lipid peroxidation in both organs. Alterations in all parameters were concentration and time dependent. The probable causes are discussed.</p></abstract>

Pesticides are designed to kill a very wide range of undesirable organisms, but they simultaneously adversely affect non-target organisms in ecosystems. Dimethoate is an organophosphorous insecticide used widely in agriculture that has an anticholinesterase mode of action. The goal of the study was to assess the effects of dimethoate on catalase, reduced glutathione, and lipid peroxidation in the gills and livers of zebrafish, Danio rerio (Hamilton), exposed to different concentrations of the pesticide for different periods of time. Insecticidal stress caused a reduction in catalase activity and reduced glutathione levels in zebrafish gills and livers. There was also increased lipid peroxidation in both organs. Alterations in all parameters were concentration and time dependent. The probable causes are discussed.

Temporal Variations of CAT, GSH, and LPO in Gills and Livers of Zebrafish, <italic>Danio Rerio,</italic> Exposed to Dimethoate

Zebrafish Laboratory, Department of Zoology D.D.U. Gorakhpur University Gorakhpur-273 009 (U.P.) India

Fisheries & Aquatic Life

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Temporal Variations of CAT, GSH, and LPO in Gills and Livers of Zebrafish,  Exposed to Dimethoate

Pesticides are designed to kill a very wide range of undesirable organisms, but they simultaneously adversely affect non-target organisms in ecosystems....

Temporal Variations of CAT, GSH, and LPO in Gills and Livers of Zebrafish, Danio Rerio, Exposed to Dimethoate

Article Category: Research Paper

Published Online: Jul 15, 2014

Page range: 101 - 109

Received: Mar 08, 2013

Accepted: Feb 02, 2014

DOI: https://doi.org/10.2478/aopf-2014-0009

Keywords
Danio rerio, dimethoate, biomarkers, oxidative stress, anti-oxidants

© 2014 Archives of Polish Fisheries

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Temporal Variations of CAT, GSH, and LPO in Gills and Livers of Zebrafish, Danio Rerio, Exposed to Dimethoate

Article Category: Research Paper

Published Online: Jul 15, 2014

Page range: 101 - 109

Received: Mar 08, 2013

Accepted: Feb 02, 2014

DOI: https://doi.org/10.2478/aopf-2014-0009

KeywordsDanio rerio, dimethoate, biomarkers, oxidative stress, anti-oxidants

© 2014 Archives of Polish Fisheries

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
Danio rerio, dimethoate, biomarkers, oxidative stress, anti-oxidants