<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Lead (Pb) and cadmium (Cd) are toxic metals occurring commonly in the human environment that show mutagenic, genotoxic and carcinogenic effects. Dietary components could prevent heavy metals intoxication by reducing their accumulation in the body. The purpose of the study was to check possible protective effect of regular consumption of white, black, red, or green tea on bone metabolism during long-term exposure to Pb and Cd in adult rats. The 12 week-long exposure to Pb and Cd (50 mg Pb and 7 mg Cd/kg of the diet) in a rat model was studied. Twelve-week-old adult male Wistar rats were randomly divided into a negative control group (Pb and Cd exposure without tea), a control (without Pb and Cd and teas), and groups co-exposed to Pb and Cd and supplemented with green, red, black, or white tea (n=12 each group). The experiment lasted for 12 weeks. The co-exposure to Pb and Cd led to the increase of bone resorption depending on the tea treatment, which was confirmed by the mechanical testing and histomorphometrical examination of cancellous bone. Pb and Cd influenced mechanical strength, reduced the densitometric and geometric parameters and the thickness of growth plate and articular cartilages. Concluding, white tea exerted the best protective effect on bone tissue and hyaline cartilage against heavy metal action.</p></abstract>

Lead (Pb) and cadmium (Cd) are toxic metals occurring commonly in the human environment that show mutagenic, genotoxic and carcinogenic effects. Dietary components could prevent heavy metals intoxication by reducing their accumulation in the body. The purpose of the study was to check possible protective effect of regular consumption of white, black, red, or green tea on bone metabolism during long-term exposure to Pb and Cd in adult rats. The 12 week-long exposure to Pb and Cd (50 mg Pb and 7 mg Cd/kg of the diet) in a rat model was studied. Twelve-week-old adult male Wistar rats were randomly divided into a negative control group (Pb and Cd exposure without tea), a control (without Pb and Cd and teas), and groups co-exposed to Pb and Cd and supplemented with green, red, black, or white tea (n=12 each group). The experiment lasted for 12 weeks. The co-exposure to Pb and Cd led to the increase of bone resorption depending on the tea treatment, which was confirmed by the mechanical testing and histomorphometrical examination of cancellous bone. Pb and Cd influenced mechanical strength, reduced the densitometric and geometric parameters and the thickness of growth plate and articular cartilages. Concluding, white tea exerted the best protective effect on bone tissue and hyaline cartilage against heavy metal action.

White Tea is More Effective in Preservation of Bone Loss in Adult Rats Co-Exposed to Lead and Cadmium Compared to Black, Red or Green Tea

Department of Animal Physiology, Faculty of Veterinary Medicine

Department of Physics, Faculty of Production Engineering

Department of Comparative Anatomy and Anthropology

Institute of Animal Nutrition and Bromatology

Annals of Animal Science

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Lead (Pb) and cadmium (Cd) are toxic metals occurring commonly in the human environment that show mutagenic, genotoxic and carcinogenic effects. Dietary...

White Tea is More Effective in Preservation of Bone Loss in Adult Rats Co-Exposed to Lead and Cadmium Compared to Black, Red or Green Tea

Published Online: Nov 02, 2018

Page range: 937 - 953

Received: Jan 26, 2018

Accepted: May 17, 2018

DOI: https://doi.org/10.2478/aoas-2018-0026

Keywords
cadmium, lead, tea, adult rats, femur, geometry, mechanical endurance

© 2018 Ewa Tomaszewska et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

White Tea is More Effective in Preservation of Bone Loss in Adult Rats Co-Exposed to Lead and Cadmium Compared to Black, Red or Green Tea

Published Online: Nov 02, 2018

Page range: 937 - 953

Received: Jan 26, 2018

Accepted: May 17, 2018

DOI: https://doi.org/10.2478/aoas-2018-0026

Keywordscadmium, lead, tea, adult rats, femur, geometry, mechanical endurance

© 2018 Ewa Tomaszewska et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
cadmium, lead, tea, adult rats, femur, geometry, mechanical endurance