<abstract xmlns="http://www.w3.org/1999/xhtml">
<sec><h3>Introduction:</h3>
<p>Melkersson Rosenthal syndrome (MRS) is a disease of multifactorial origin typically presented with a triad of symptoms including peripheral facial nerve paralysis, plicated tongue and orofacial edema. Diagnosing MRS requires the exclusion of other granulomatous diseases and the correlation of clinical with histopathological finding.</p>
</sec>
<sec><h3>Case presentation:</h3>
<p>We present the case of a 56-year-old female with a four-month history of lower lip and right mandible angle swelling together with a plicated tongue that appeared during COVID-19 infection. The patient was successfully treated with intralesional Triamcinolone Acetonide at a dose of 40 mg.</p>
</sec>
<sec><h3>Conclusion: </h3>
<p>The presented case is specific by its late onset since the patient experienced their first symptoms in fifties, which differs from the majority of cases where the diagnosis is usually established in young adults. Infectious factors are established as possible etiologic factors of MRS, but few cases are described to be triggered or worsened by COVID-19 infection.</p>
</sec>
</abstract>

Introduction:
Melkersson Rosenthal syndrome (MRS) is a disease of multifactorial origin typically presented with a triad of symptoms including peripheral facial nerve paralysis, plicated tongue and orofacial edema. Diagnosing MRS requires the exclusion of other granulomatous diseases and the correlation of clinical with histopathological finding.

Case presentation:
We present the case of a 56-year-old female with a four-month history of lower lip and right mandible angle swelling together with a plicated tongue that appeared during COVID-19 infection. The patient was successfully treated with intralesional Triamcinolone Acetonide at a dose of 40 mg.

Conclusion: 
The presented case is specific by its late onset since the patient experienced their first symptoms in fifties, which differs from the majority of cases where the diagnosis is usually established in young adults. Infectious factors are established as possible etiologic factors of MRS, but few cases are described to be triggered or worsened by COVID-19 infection.

Oligosymptomatic form of Melkersson-Rosenthal Syndrome possibly triggered by COVID-19 infection: A case report

Department of Pathology, Faculty of Medicine University of Sarajevo

Department of Dermatovenerology, Sarajevo Medical School, University of Sarajevo School of Science and Technology

Acta Marisiensis - Seria Medica

This work is licensed under the Creative Commons Attribution 4.0 International License.

Introduction:
Melkersson Rosenthal syndrome (MRS) is a disease of multifactorial origin typically presented with a triad of symptoms including peripheral...

Oligosymptomatic form of Melkersson-Rosenthal Syndrome possibly triggered by COVID-19 infection: A case report

Published Online: Apr 03, 2024

Page range: 27 - 30

Received: Jan 05, 2024

Accepted: Feb 26, 2024

DOI: https://doi.org/10.2478/amma-2024-0004

Keywords
Melkersson-Rosenthal syndrome, granulomatous cheilitis, COVID-19, oligosymptomatic

© 2024 Nisada Đuzelić et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Oligosymptomatic form of Melkersson-Rosenthal Syndrome possibly triggered by COVID-19 infection: A case report

Published Online: Apr 03, 2024

Page range: 27 - 30

Received: Jan 05, 2024

Accepted: Feb 26, 2024

DOI: https://doi.org/10.2478/amma-2024-0004

KeywordsMelkersson-Rosenthal syndrome, granulomatous cheilitis, COVID-19, oligosymptomatic

© 2024 Nisada Đuzelić et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Keywords
Melkersson-Rosenthal syndrome, granulomatous cheilitis, COVID-19, oligosymptomatic