<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Over the past years, prevention and control of risk factors has begun to play an important role in the management of patients prone to develop atrial fibrillation (AF). A considerable number of risk factors that contribute to the creation of a predisposing substrate for AF has been identified over the years. Although certain AF risk factors such as age, gender, genetic predisposition, or race are unmodifiable, controlling modifiable risk factors may represent an invaluable tool in the management of AF patients. In the recent decades, numerous studies have evaluated the mechanisms linking different risk factors to AF, but the exact degree of atrial remodeling induced by each factor remains unknown. Elucidating these mechanisms is essential for initiating personalized therapies in patients prone to develop AF. The present review aims to provide an overview of the most relevant modifiable risk factors involved in AF occurrence, with a focus on the mechanisms by which these factors lead to AF initiation and perpetuation.</p></abstract>

Over the past years, prevention and control of risk factors has begun to play an important role in the management of patients prone to develop atrial fibrillation (AF). A considerable number of risk factors that contribute to the creation of a predisposing substrate for AF has been identified over the years. Although certain AF risk factors such as age, gender, genetic predisposition, or race are unmodifiable, controlling modifiable risk factors may represent an invaluable tool in the management of AF patients. In the recent decades, numerous studies have evaluated the mechanisms linking different risk factors to AF, but the exact degree of atrial remodeling induced by each factor remains unknown. Elucidating these mechanisms is essential for initiating personalized therapies in patients prone to develop AF. The present review aims to provide an overview of the most relevant modifiable risk factors involved in AF occurrence, with a focus on the mechanisms by which these factors lead to AF initiation and perpetuation.

Atrial Fibrillation – An Orchestra of Classic and Modern Risk Factors

University of Medicine and Pharmacy Science and Technology of Targu Mures

Acta Marisiensis - Seria Medica

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"Atrial Fibrillation \u2013 An Orchestra of Classic and Modern Risk Factors"}

Over the past years, prevention and control of risk factors has begun to play an important role in the management of patients prone to develop atrial...

Atrial Fibrillation – An Orchestra of Classic and Modern Risk Factors

Published Online: Sep 26, 2019

Page range: 80 - 86

Received: May 30, 2019

Accepted: Aug 04, 2019

DOI: https://doi.org/10.2478/amma-2019-0020

Keywords
atrial fibrillation, epidemiology, mechanisms, remodeling, risk factors

© 2019 Alkora Ioana Balan et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Atrial Fibrillation – An Orchestra of Classic and Modern Risk Factors

Published Online: Sep 26, 2019

Page range: 80 - 86

Received: May 30, 2019

Accepted: Aug 04, 2019

DOI: https://doi.org/10.2478/amma-2019-0020

Keywordsatrial fibrillation, epidemiology, mechanisms, remodeling, risk factors

© 2019 Alkora Ioana Balan et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
atrial fibrillation, epidemiology, mechanisms, remodeling, risk factors