[1. Beale JM jr. Synthetic antibacterial agents, in Block JH, Beale JM (eds): Wilson and Gisvold’s Textbook of Organic Medicinal and Pharmaceutical Chemistry 11th edition. Lippincott Williams & Wilkins. Philadelphia, 2004, 247-258.]Search in Google Scholar
[2. Andersson MI, MacGowan AO. Development of the quinolones. J Antimicrob Chemother. 2003;51:1-11.10.1093/jac/dkg212]Search in Google Scholar
[3. Bolon MK. The newer fluoroquinolone. Med Clin N Am. 2011;95:793-811.10.1016/j.mcna.2011.03.006]Search in Google Scholar
[4. Jimidar MI. Theoretical considerations in performance of various modes of CE, in Ahuja S, Jimidar M (eds): Capillary Electrophoresis Methods for Pharmaceutical Analysis, Volume 9 (Separation Science and Technology) 1 edition. Academic Press Elsevier, Amsterdam, 2008, 9-42.10.1016/S0149-6395(07)00002-5]Search in Google Scholar
[5. Pérez-Ruiz T, Martínez-Lozano C, Sanz A, Bravo E. Separation and simultaneous determination of quinolone antibiotics by capillary zone electrophoresis. Chromatographia. 1999;49:419-423.10.1007/BF02467617]Search in Google Scholar
[6. Sun H, He P, Lv Y, Liang S. Effective separation and simultaneous determination of seven fluoroquinolones by capillary electrophoresis with diode-array detector. J Chromatogr B. 2007;852:145-151.10.1016/j.jchromb.2007.01.016]Search in Google Scholar
[7. Ferdig M, Kaleta A, Thanh Vo TD, Buchberger W. Improved capillary electrophoretic separation of nine (fluoro)quinolones with fluorescence detection for biological and environmental samples. Journal of Chromatography A. 2004;1047:305-311.10.1016/S0021-9673(04)01102-1]Search in Google Scholar
[8. Yang Z, Qin W. Separation of fluoroquinolones in acidic buffer by capillary electrophoresis with contactless conductivity detection. J Chromatogr A. 2009;1216:5327-5332.10.1016/j.chroma.2009.05.014]Search in Google Scholar
[9. Faria AF, de Souza MVN, de Almeida MV, de Oliveira MAL. Simoultaneous separation of five fluoroquinolone antibiotics by capillary zone electrophoresis. Anal Chim Acta. 2006;579:185-192.10.1016/j.aca.2006.07.037]Search in Google Scholar
[10. Sun J, Sakai S, Tauchi Y, et al. Determination of lipophilicity of two quinolone antibacterials, ciprofloxacin and grepafloxacin, in the protonation equilibrium. Eur J Pharm Biopharm. 2002;54:51-58.10.1016/S0939-6411(02)00018-8]Search in Google Scholar
[11. Lemaire S, Tulkens PM, Van Bambeke F. Contrasting effects of acidic pH on the extracellular and intracellular activities of the anti-gram-positive fluoroquinolones moxifloxacin and delafloxacin against Staphylococcus aureus. Antimicrob Agents Ch. 2011;55:649-658.10.1128/AAC.01201-10302875321135179]Search in Google Scholar
[12. Noszál B. Acid-base properties of bioligands, in K. Burger (eds): Biocoordination chemistry: coordination equilibra in biologically active system. Ellis Horwood, Chichester UK, 1990, 18-41.]Search in Google Scholar
[13. Lee DS, Hun HJ, Kim K, et al. Dissociation and complexation of fl uoroquinolone analogues. J Pharm Biomed Anal. 1994;12:157-164.10.1016/0731-7085(94)90025-6]Search in Google Scholar
[14. Rusu A, Tóth G, Szőcs L, et al. Triprotic site-specific acid-base equilibria and related properties of fluoroquinolone antibacterials. J Pharm Biomed Anal. 2012;66:50-57.10.1016/j.jpba.2012.02.024]Search in Google Scholar
[15. Lin CE, Deng YJ, Liao WS, et al. Electrophoretic behavior and pKa determination of quinolones with a piperazinyl substituent by capillary zone electrophoresis. J Chromatogr A. 2004;1051:283-290.10.1016/S0021-9673(04)01422-0]Search in Google Scholar
[16. Lombardo-Agüí M, García-Campana AM, Gámiz-Gracia L, Cruces Blanco C. Laser induced fluorescence coupled to capillary electrophoresis for the determination of fluoroquinolones in foods of animal origin using molecularly imprinted polymers. J Chromatogr A. 2010;1217: 2237-2242.10.1016/j.chroma.2010.02.016]Search in Google Scholar
[17. Yang Z, Qin W. Separation of fluoroquinolones in acidic buffer by capillary electrophoresis with contactless conductivity detection. J Chromatogr A. 2009;1216:5327-5332.10.1016/j.chroma.2009.05.014]Search in Google Scholar
[18. European Pharmacopoeia 7th edition. Council of Europe, Strasbourg, 2010, 367.]Search in Google Scholar
[19. Drakopoulos AI, Ioannou PC. Spectrofluorimetric study of the acid-base equilibria and complexation behavior of the fluoroquinolone antibiotics ofloxacin, norfloxacin, ciprofloxacin and pefloxacin in aqueous solution.]Search in Google Scholar
[Anal Chim Acta. 1997;354:197-204.10.1016/S0003-2670(97)00465-0]Search in Google Scholar
[20. Park HR, Kim TH, Bark KM. Physicochemical properties of quinolone antibiotics in various environments. Eur J Med Chem. 2002;37:443-460.10.1016/S0223-5234(02)01361-2]Search in Google Scholar
[21. Barbosa J, Barrón D, Jiménez-Lozano E, Sanz-Nebot V. Comparison between capillary electrophoresis, liquid chromatography, potentiometric and spectrophotometric techniques for evaluation of pKa values of zwitterionic drugs in acetonitrile-water mixtures. Anal Chim Acta. 2001;437:309-321.10.1016/S0003-2670(01)00997-7]Search in Google Scholar
[22. Jiménez-Lozano E, Marqués I, Barrón D, Beltrán JL, Barbosa J.]Search in Google Scholar
[Determination of pKa values of quinolones from mobility and spectroscopic data obtained by CE and a DAD. Anal Chim Acta. 2002;464:37-45.10.1016/S0003-2670(02)00435-X]Search in Google Scholar
[23. Langlois MH, Montagut M, Dubost JP, Grellet J, Saux MC. Protonation equilibrium and lipophilicity of moxifloxacin. J Pharm Biomed Anal. 2005;37:389-393.10.1016/j.jpba.2004.10.02215708683]Search in Google Scholar
[24. Lorenzo F, Navaratnam S, Edge R, Allen NS. Primary Photophysical Properties of Moxifloxacin - A Fluoroquinolone Antibiotic. Photochem Photobiol. 2008;84:1118-1125.10.1111/j.1751-1097.2007.00269.x]Search in Google Scholar
[25. Neves P, Leite A, Rangel M, de Castro B, Gameiro P. Influence of structural factors on the enhanced activity of moxifloxacin: a fluorescence and EPR spectroscopic study, Anal Bioanal Chem. 2007;387:1543-1552.]Search in Google Scholar
[26. Takács-Novák K, Noszál B, Hermecz I, et al. Protonation equilibria of quinolone antibacterials. J Pharm Sci. 1990;79:1023-1028.10.1002/jps.2600791116]Search in Google Scholar
[27. Altria KD. Introduction to CE and the Use of CE in Pharmaceutycal Analysis, in Altria KD (eds): Analysis of Pharmaceuticals by Capillary Electrophoresis. Chromatographia CE-Series, Vieweg, 1998, 1-18.10.1007/978-3-322-85011-9_1]Search in Google Scholar
[28. Sänger-van de Griend CE. General Considerations to Improve Performance of CE Methods, in Ahuja S, Jimidar M (eds): Capillary Electrophoresis Methods for Pharmaceutical Analysis. Elsevier/Academic Press, Amsterdam, 2008, 123-144.10.1016/S0149-6395(07)00006-2]Search in Google Scholar
[29. ICH. Validation of analytical procedures: text and methodology Q2(R1).]Search in Google Scholar
[Geneva, 2005]Search in Google Scholar
[30. Peters FT, Drummer OH, Musshoff F. Validation of new methods. Forensic Sci Int. 2007;165:216-224.10.1016/j.forsciint.2006.05.02116781833]Search in Google Scholar
[31. Peters FT, Maurer HH. Bioanalytical method validation and its implications for forensic and clinical toxicology - A review, in De Bièvre P, Günzler H (eds.): Validation in Chemical Measurement, Springer-Verlag, Berlin Heidelberg, 2005, 1-9.10.1007/3-540-27034-5_1]Search in Google Scholar
[32. Ross GA. Instrumental validation in capillary electrophoresis and checkpoints for method validation, in De Bièvre P, Günzler H (eds.): Validation in Chemical Measurement, Springer-Verlag, Berlin Heidelberg, 2005, 14-23. 10.1007/3-540-27034-5_3]Search in Google Scholar