<abstract xmlns="http://www.w3.org/1999/xhtml"><p>We present a case of a necrotising disease of the orofacial tissues, the so-called noma, in a female patient with AIDS in a stage of severe immune deficiency. To our knowledge, this is the first time a case like that has been reported in Bulgaria. The patient received an antibiotic course of treatment with a triple combination to good effect on the inflammatory process, and began also HAART. Within 3 weeks, the patient’s general condition improved. However, despite the treatment, a demarcation line was formed, and a defect on the lower lip occurred. Noma is a manifestation of severe immune deficiency with lasting adverse consequences for the patient: severe deformation of the maxilo-facial region and functional impairment (i.e. difficulties eating and speaking, and salivary leak).</p></abstract>

We present a case of a necrotising disease of the orofacial tissues, the so-called noma, in a female patient with AIDS in a stage of severe immune deficiency. To our knowledge, this is the first time a case like that has been reported in Bulgaria. The patient received an antibiotic course of treatment with a triple combination to good effect on the inflammatory process, and began also HAART. Within 3 weeks, the patient’s general condition improved. However, despite the treatment, a demarcation line was formed, and a defect on the lower lip occurred. Noma is a manifestation of severe immune deficiency with lasting adverse consequences for the patient: severe deformation of the maxilo-facial region and functional impairment (i.e. difficulties eating and speaking, and salivary leak).

First Case of Cancrum Oris (Noma) in an HIV-Positive Patient in Bulgaria

Department for Infectious Diseases, Parasitology and Tropical Medicine

Acta Medica Bulgarica

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"First Case of Cancrum Oris (Noma) in an HIV-Positive Patient in Bulgaria"}

We present a case of a necrotising disease of the orofacial tissues, the so-called noma, in a female patient with AIDS in a stage of severe immune deficiency....

First Case of Cancrum Oris (Noma) in an HIV-Positive Patient in Bulgaria

Published Online: Oct 14, 2020

Page range: 34 - 37

Accepted: Jul 27, 2020

DOI: https://doi.org/10.2478/amb-2020-0032

Keywords
HIV, noma, immune deficiency, facial disfigurement

© 2020 R. Grozdeva et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

First Case of Cancrum Oris (Noma) in an HIV-Positive Patient in Bulgaria

Published Online: Oct 14, 2020

Page range: 34 - 37

Accepted: Jul 27, 2020

DOI: https://doi.org/10.2478/amb-2020-0032

KeywordsHIV, noma, immune deficiency, facial disfigurement

© 2020 R. Grozdeva et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
HIV, noma, immune deficiency, facial disfigurement