Open Access

Myofibroblasts in Normal and Fibrotic Liver in Different Animal Species


Cite

1. Anthony B, Allen JT, Li YS, McManus DP: Hepatic stellate cells and parasite-induced liver fibrosis. Parasit Vectors 2010, 3(1):60, doi: 10.1186/1756-3305-3-60.10.1186/1756-3305-3-60291596920663176Search in Google Scholar

2. Wynn TA: Cellular and molecular mechanisms of fi brosis. J Pathol 2008, 214(2):199-210.10.1002/path.2277269332918161745Search in Google Scholar

3. Jiroutova A, Peterova E, Bittnerova L, Slavkovsky R, Cevelova P, Rezacova M, Cerman J, Micuda S, Kanta J: Collagenolytic potential of rat liver myofi broblasts. Physiol Res 2013, 62(1):15-25.10.33549/physiolres.93239923173684Search in Google Scholar

4. Parola M, Pinzani M: Hepatic wound repair. Fibrogenesis Tissue Repair 2009, 2(1):4, doi: 10.1186/1755-1536-2-4.10.1186/1755-1536-2-4276050819781064Search in Google Scholar

5. Benyon RC, Iredale JP: Is liver fi brosis reversible? Gut 2000, 46(4):443-446.10.1136/gut.46.4.443172790410716665Search in Google Scholar

6. Lemoinne S, Cadoret A, El Mourabit H, Thabut D, Housset C: Origins and functions of liver myofi broblasts. Biochim Biophys Acta 2013, 1832(7):948-954.10.1016/j.bbadis.2013.02.01923470555Search in Google Scholar

7. Brenner DA: Molecular pathogenesis of liver fi brosis. Trans Am Clin Climatol Assoc 2009, 120:361-368.Search in Google Scholar

8. Hinz B, Phan SH, Thannickal VJ, Galli A, Bochaton-Piallat ML, Gabbiani G: The myofi broblast: one function, multiple origins. Am J Pathol 2007, 170(6):1807-1816.10.2353/ajpath.2007.070112189946217525249Search in Google Scholar

9. Kendall RT, Feghali-Bostwick CA: Fibroblasts in fibrosis: novel roles and mediators. Front Pharmacol 2014, 5:123, doi: 10.3389/fphar.2014.00123.10.3389/fphar.2014.00123403414824904424Search in Google Scholar

10. Guyot C, Lepreux S, Combe C, Doudnikoff E, Bioulac-Sage P, Balabaud C, Desmouliere A: Hepatic fibrosis and cirrhosis: the (myo)fibroblastic cell subpopulations involved. Int J Biochem Cell Biol 2006, 38(2):135-151.10.1016/j.biocel.2005.08.02116257564Search in Google Scholar

11. Honda E, Park AM, Yoshida K, Tabuchi M, Munakata H: Myofibroblasts: Biochemical and proteomic approaches to fibrosis. Tohoku J Exp Med 2013, 230(2):67-73.10.1620/tjem.230.6723774326Search in Google Scholar

12. Xu J, Liu X, Koyama Y, Wang P, Lan T, Kim IG, Kim IH, Ma HY, Kisseleva T: The types of hepatic myofibroblasts contributing to liver fi brosis of different etiologies. Front Pharmacol 2014, 5:167, doi: 10.3389/fphar.2014.00167.10.3389/fphar.2014.00167Search in Google Scholar

13. Cassiman D, Libbrecht L, Desmet V, Denef C, Roskams T: Hepatic stellate cell/ myofibroblast subpopulations in fibrotic human and rat livers. J Hepatol 2002, 36(2):200-209.10.1016/S0168-8278(01)00260-4Search in Google Scholar

14. Ijzer J, Roskams T, Molenbeek RF, Ultee T, Penning LC, Rothuizen J, van den Ingh TS: Morphological characterisation of portal myofibroblasts and hepatic stellate cells in the normal dog liver. Comp Hepatol 2006, 5:7, doi:10.1186/1476-5926-5-7.10.1186/1476-5926-5-7166057817109742Search in Google Scholar

15. Kisseleva T, Cong M, Paik Y, Scholten D, Jiang C, Benner C, Iwaisako K, Moore-Morris T, Scott B, Tsukamoto H, Evans SM, Dillmann W, Glass CK, Brenner DA: Myofibroblasts revert to an inactive phenotype during regression of liver fi brosis. Proc Natl Acad Sci U S A 2012, 109(24):9448-9453.10.1073/pnas.1201840109338611422566629Search in Google Scholar

16. Parola M, Marra F, Pinzani M: Myofibroblast - like cells and liver fi brogenesis: Emerging concepts in a rapidly moving scenario. Mol Aspects Med 2008, 29(1-2):58-66.10.1016/j.mam.2007.09.00218022682Search in Google Scholar

17. Ramadori G, Saile B: Portal tract fibrogenesis in the liver. Lab Invest 2004, 84(2):153-159.10.1038/labinvest.370003014688800Search in Google Scholar

18. Iwaisako K, Jiang C, Zhang M, Cong M, Moore-Morris TJ, Park TJ, Liu X, Xu J, Wang P, Paik YH et al: Origin of myofi broblasts in the fibrotic liver in mice. Proc Natl Acad Sci U S A 2014, 111(32):E3297-3305.10.1073/pnas.1400062111413660125074909Search in Google Scholar

19. Bataller R, Brenner DA: Liver fibrosis. J Clin Invest 2005, 115(2):209-218.10.1172/JCI2428254643515690074Search in Google Scholar

20. Kinnman N, Housset C: Peribiliary myofibroblasts in biliary type liver fibrosis. Front Biosci 2002, 7:d496-503.10.2741/A79011815289Search in Google Scholar

21. Tuchweber B, Desmouliere A, Bochaton-Piallat ML, Rubbia-Brandt L, Gabbiani G: Proliferation and phenotypic modulation of portal fibroblasts in the early stages of cholestatic fibrosis in the rat. Lab Invest 1996, 74(1):265-278.Search in Google Scholar

22. Iwaisako K, Brenner DA, Kisseleva T: What’s new in liver fi brosis? The origin of myofi broblasts in liver fibrosis. J Gastroenterol Hepatol 2012, 27 Suppl 2:65-68.10.1111/j.1440-1746.2011.07002.x484126822320919Search in Google Scholar

23. Brenner DA, Kisseleva T, Scholten D, Paik YH, Iwaisako K, Inokuchi S, Schnabl B, Seki E, De Minicis S, Oesterreicher C, Taura K: Origin of myofi broblasts in liver fibrosis. Fibrogenesis Tissue Repair 2012, 5 Suppl 1:S17.10.1186/1755-1536-5-S1-S17336877523259769Search in Google Scholar

24. Fausther M, Lavoie EG, Dranoff JA: Contribution of Myofibroblasts of Different Origins to Liver Fibrosis. Curr Pathobiol Rep 2013, 1(3):225-230.10.1007/s40139-013-0020-0375577923997993Search in Google Scholar

25. Forbes SJ, Parola M: Liver fibrogenic cells. Best Pract Res Clin Gastroenterol 2011, 25(2):207-217.10.1016/j.bpg.2011.02.00621497739Search in Google Scholar

26. Kisseleva T, Brenner DA: Mechanisms of fibrogenesis. Exp Biol Med (Maywood) 2008, 233(2):109-122.10.3181/0707-MR-19018222966Search in Google Scholar

27. Novo E, Cannito S, Paternostro C, Bocca C, Miglietta A, Parola M: Cellular and molecular mechanisms in liver fibrogenesis. Arch Biochem Biophys 2014, 548C:20-37.10.1016/j.abb.2014.02.01524631571Search in Google Scholar

28. 28. Novo E, di Bonzo LV, Cannito S, Colombatto S, Parola M: Hepatic myofibroblasts: a heterogeneous population of multifunctional cells in liver fibrogenesis. Int J Biochem Cell Biol 2009, 41(11):2089-2093.10.1016/j.biocel.2009.03.01019782946Search in Google Scholar

29. Iwano M, Plieth D, Danoff TM, Xue C, Okada H, Neilson EG: Evidence that fibroblasts derive from epithelium during tissue fibrosis. J Clin Invest 2002, 110(3):341-350.10.1172/JCI0215518Search in Google Scholar

30. Kalluri R, Neilson EG: Epithelial-mesenchymal transition and its implications for fibrosis. J Clin Invest 2003, 112(12):1776-1784.10.1172/JCI200320530Search in Google Scholar

31. Robertson H, Kirby JA, Yip WW, Jones DE, Burt AD: Biliary epithelial-mesenchymal transition in posttransplantation recurrence of primary biliary cirrhosis. Hepatology 2007, 45(4):977-981.10.1002/hep.2162417393507Search in Google Scholar

32. Hautekeete ML, Geerts A: The hepatic stellate (Ito) cell: its role in human liver disease. Virchows Arch 1997, 430(3):195-207.10.1007/BF013248029099976Search in Google Scholar

33. Jing XY, Yang XF, Qing K, Ou-yang Y: Roles of the lipid metabolism in hepatic stellate cells activation big up tri, open. Chin Med Sci J 2013, 28(4):233-236.10.1016/S1001-9294(14)60008-0Search in Google Scholar

34. Mallat A, Lotersztajn S: Reversion of hepatic stellate cell to a quiescent phenotype: From myth to reality? J Hepatol 2013, 59(2):383-386.10.1016/j.jhep.2013.03.03123567083Search in Google Scholar

35. Senoo H: Structure and function of hepatic stellate cells. Med Electron Microsc 2004, 37(1):3-15.10.1007/s00795-003-0230-315057600Search in Google Scholar

36. Atzori L, Poli G, Perra A: Hepatic stellate cell: a star cell in the liver. Int J Biochem Cell Biol 2009, 41(8-9):1639-1642.10.1016/j.biocel.2009.03.00119433304Search in Google Scholar

37. Burt AD: Pathobiology of hepatic stellate cells. J Gastroenterol 1999, 34(3):299-304.10.1007/s00535005026410433002Search in Google Scholar

38. Friedman SL, Rockey DC, McGuire RF, Maher JJ, Boyles JK, Yamasaki G: Isolated hepatic lipocytes and Kupffer cells from normal human liver: morphological and functional characteristics in primary culture. Hepatology 1992, 15(2):234-243.10.1002/hep.18401502111735526Search in Google Scholar

39. Reeves HL, Friedman SL: Activation of hepatic stellate cells--a key issue in liver fibrosis. Front Biosci 2002, 7:d808-826.10.2741/A813Search in Google Scholar

40. Friedman SL: Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury. J Biol Chem 2000, 275(4):2247-2250.10.1074/jbc.275.4.224710644669Search in Google Scholar

41. Moreira RK: Hepatic stellate cells and liver fibrosis. Arch Pathol Lab Med 2007, 131(11):1728-1734. 10.5858/2007-131-1728-HSCALF17979495Search in Google Scholar

42. Friedman SL: Hepatic fibrosis -- overview. Toxicology 2008, 254(3):120-129.10.1016/j.tox.2008.06.01318662740Search in Google Scholar

43. Safadi R, Friedman SL: Hepatic fibrosis--role of hepatic stellate cell activation. MedGenMed 2002, 4(3):27.Search in Google Scholar

44. Kramann R, DiRocco DP, Humphreys BD: Understanding the origin, activation and regulation f matrix-producing myofibroblasts for treatment of fi brotic disease. J Pathol 2013, 231(3):273-289.10.1002/path.425324006178Search in Google Scholar

45. Liu X, Xu J, Brenner DA, Kisseleva T: Reversibility of Liver Fibrosis and Inactivation of Fibrogenic Myofi broblasts. Curr Pathobiol Rep 2013, 1(3):209-214.10.1007/s40139-013-0018-7375725224000319Search in Google Scholar

46. Gressner OA, Gao C: Monitoring fi brogenic progression in the liver. Clin Chim Acta 2014, 433C:111-122.10.1016/j.cca.2014.02.02124607331Search in Google Scholar

47. Micallef L, Vedrenne N, Billet F, Coulomb B, Darby IA, Desmouliere A: The myofibroblast, multiple origins for major roles in normal and pathological tissue repair. Fibrogenesis Tissue Repair 2012, 5 Suppl 1:S5.10.1186/1755-1536-5-S1-S5336878923259712Search in Google Scholar

48. Jiang JX, Torok NJ: Liver Injury and the Activation of the Hepatic Myofi broblasts. Curr Pathobiol Rep 2013, 1(3):215-223.10.1007/s40139-013-0019-6374897223977452Search in Google Scholar

49. Rao KB, Malathi N, Narashiman S, Rajan ST: Evaluation of myofibroblasts by expression of alpha smooth muscle actin: a marker in fibrosis, dysplasia and carcinoma. J Clin Diagn Res 2014, 8(4):ZC14-17.Search in Google Scholar

50. Rockey DC, Weymouth N, Shi Z: Smooth muscle alpha actin (Acta2) and myofibroblast function during hepatic wound healing. PLoS One 2013, 8(10):e77166, doi: 10.1371/ journal.pone.0077166.10.1371/journal.pone.0077166381216524204762Search in Google Scholar

51. Lepreux S, Dubuisson L, Le Bail B, Desmouliere A, Balabaud C, Bioulac-Sage P: Can hepatic stellate cells express alpha-smooth muscle actin in normal human liver? Liver 2001, 21(4):293-294.10.1034/j.1600-0676.2001.021004293.x11454194Search in Google Scholar

52. Gibelli NE, Tannuri U, Mello ES: Immunohistochemical studies of stellate cells in experimental cholestasis in newborn and adult rats. Clinics (Sao Paulo) 2008, 63(5):689-694.10.1590/S1807-59322008000500019Search in Google Scholar

53. Wells RG: The role of matrix stiffness in hepatic stellate cell activation and liver fibrosis. J Clin Gastroenterol 2005, 39(4 Suppl 2):S158-161.10.1097/01.mcg.0000155516.02468.0f15758652Search in Google Scholar

54. Dranoff JA, Wells RG: Portal fibroblasts: Underappreciated mediators of biliary fibrosis. Hepatology 2010, 51(4):1438-1444.10.1002/hep.23405285094620209607Search in Google Scholar

55. Senda T, Nomura R: The expression of cytokeratin in hepatic stellate cells of the cod. Arch Histol Cytol 2003, 66(5):437-444.10.1679/aohc.66.437Search in Google Scholar

56. Handharyani E, Ochiai K, Iwata N, Umemura T: Immunohistochemical and ultrastructural study of ito cells (fat-storing cells) in response to extrahepatic bile duct ligation in broiler chickens. J Vet Med Sci 2001, 63(5):547-552.10.1292/jvms.63.547Search in Google Scholar

57. Knittel T, Kobold D, Piscaglia F, Saile B, Neubauer K, Mehde M, Timpl R, Ramadori G: Localization of liver myofi broblasts and hepatic stellate cells in normal and diseased rat livers: distinct roles of (myo-)fibroblast subpopulations in hepatic tissue repair. Histochem Cell Biol 1999, 112(5):387-401.10.1007/s004180050421Search in Google Scholar

58. Zhao L, Burt AD: The diffuse stellate cell system. J Mol Histol 2007, 38(1):53-64.10.1007/s10735-007-9078-5Search in Google Scholar

59. Rubbia-Brandt L, Mentha G, Desmouliere A, Alto Costa AM, Giostra E, Molas G, Enzan H, Gabbiani G: Hepatic stellate cells reversibly express alpha-smooth muscle actin during acute hepatic ischemia. Transplant Proc 1997, 29(5):2390-2395.10.1016/S0041-1345(97)00415-6Search in Google Scholar

60. Knežević M, Gledić D, Kukolj V, Knežević D, Jovanović M, Božić T, Aleksić-Kovačević S: Expression of α-SMA, desmin and vimentin in canine liver with fibrosis. Acta Veterinaria (Beograd) 2009, 59(4):361-370. 10.2298/AVB0904361KSearch in Google Scholar

61. Aleksić-Kovačević S, Kukolj V, Kureljušić B, Marinković D, Knežević D, Ignjatović I, Jovanović M, Knežević M, Gledić D: Role of hepatic stellate cells (HSCs) in the development of hepatic fibrosis in cats with polycystic kidney disease (PKD). Acta Veterinaria (Beograd) 2010, 60(4):391-400.10.2298/AVB1004391ASearch in Google Scholar

62. Uetsuka K, Nishikawa S, Isobe K, Nakayama H: Histopathological characteristics of Kupffer cells and ito cells in the porcine and bovine liver. J Vet Med Sci 2007, 69(7):767-770.10.1292/jvms.69.76717675812Search in Google Scholar

63. Marinkovic D, Kukolj V, Aleksic-Kovacevic S, Jovanovic M, Knezevic M: The role of hepatic myofibroblasts in liver cirrhosis in fallow deer (Dama dama) naturally infected with giant liver fl uke (Fascioloides magna). BMC Vet Res 2013, 9:45, doi: 10.1186/1746-6148-9-45.10.1186/1746-6148-9-45361446723497565Search in Google Scholar

64. Maria De Souza M, Tolentino M, Jr., Assis BC, Cristina De Oliveira Gonzalez A, Maria Correia Silva T, Andrade ZA: Pathogenesis of septal fibrosis of the liver. (An experimental study with a new model.). Pathol Res Pract 2006, 202(12):883-889.10.1016/j.prp.2006.07.00417023120Search in Google Scholar

65. Ide M, Yamate J, Kuwamura M, Kotani T, Sakuma S, Takeya M: Immunohistochemical analysis of macrophages and myofi broblasts appearing in hepatic and renal fi brosis of dogs. J Comp Pathol 2001, 124(1):60-69.10.1053/jcpa.2000.042911428190Search in Google Scholar

66. Mekonnen GA, Ijzer J, Nederbragt H: Tenascin-C in chronic canine hepatitis: immunohistochemical localization and correlation with necro-infl ammatory activity, fibrotic stage, and expression of alpha-smooth muscle actin, cytokeratin 7, and CD3+ cells. Vet Pathol 2007, 44(6):803-813.10.1354/vp.44-6-80318039893Search in Google Scholar

67. Golbar HM, Izawa T, Juniantito V, Ichikawa C, Tanaka M, Kuwamura M, Yamate J: Immunohistochemical characterization of macrophages and myofibroblasts in fibrotic liver lesions due to Fasciola infection in cattle. J Vet Med Sci 2013, 75(7):857-865. 10.1292/jvms.12-053623411482Search in Google Scholar

eISSN:
1820-7448
Language:
English
Publication timeframe:
4 times per year
Journal Subjects:
Medicine, Veterinary Medicine