<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Piperazine derivatives are a group of compounds with a psychostimulant effect. They are an alternative to illegal drugs. They are being searched for recreational use due to their psychoactive and hallucinogenic effects. The high popularity of these compounds can be noticed all over the world due to easy purchase, lack of legal regulations and incorrect assessment of the safety of use. The recreational use of piperazine derivatives can often result in chronic and acute health problems and additionally with unpredictable remote effects. It is also common to take mixtures of psychoactive compounds. This hinders the correct diagnosis and treatment of patients with poisoning. The presented work is an illustration of the wide problem of piperazine derivatives abuse. The health effects and the possibility of identifying these compounds in preparations and biological material are described.</p></abstract>

Piperazine derivatives are a group of compounds with a psychostimulant effect. They are an alternative to illegal drugs. They are being searched for recreational use due to their psychoactive and hallucinogenic effects. The high popularity of these compounds can be noticed all over the world due to easy purchase, lack of legal regulations and incorrect assessment of the safety of use. The recreational use of piperazine derivatives can often result in chronic and acute health problems and additionally with unpredictable remote effects. It is also common to take mixtures of psychoactive compounds. This hinders the correct diagnosis and treatment of patients with poisoning. The presented work is an illustration of the wide problem of piperazine derivatives abuse. The health effects and the possibility of identifying these compounds in preparations and biological material are described.

Piperazine derivatives as dangerous abused compounds

Department of Toxicology Faculty of Pharmacy

Collegium Medicum Nicolaus Copernicus University

Acta Pharmaceutica

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"Piperazine derivatives as dangerous abused compounds"}

Piperazine derivatives are a group of compounds with a psychostimulant effect. They are an alternative to illegal drugs. They are being searched for...

Piperazine derivatives as dangerous abused compounds

Published Online: May 13, 2020

Page range: 423 - 441

Accepted: Dec 03, 2019

DOI: https://doi.org/10.2478/acph-2020-0035

Keywords
piperazine derivatives, designer drugs, benzylpiperazine, phenylpiperazine, addiction

© 2020 Anna Welz et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Piperazine derivatives as dangerous abused compounds

Published Online: May 13, 2020

Page range: 423 - 441

Accepted: Dec 03, 2019

DOI: https://doi.org/10.2478/acph-2020-0035

Keywordspiperazine derivatives, designer drugs, benzylpiperazine, phenylpiperazine, addiction

© 2020 Anna Welz et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
piperazine derivatives, designer drugs, benzylpiperazine, phenylpiperazine, addiction