Bioadhesive vaginal tablets containing spray dried microspheres loaded with clotrimazole for treatment of vaginal Candidiasis

1. A. H. F. Ahsan and A. Hussain, The vagina as a route for systemic drug delivery, J. Control. Release 103 (2005) 301-313; DOI: 10.1016/j.jconrel.2004.11.034.10.1016/j.jconrel.2004.11.034Search in Google Scholar

2. H. Y. Karasulu, S. Hilmioglu, D. Y. Metin and T. Guneri, Efficacy of a new ketoconazole bioadhesive vaginal tablet on candida albicans, Farmaco 59 (2004) 163-167; DOI: 10.1016/j.farmac. 2003.11.018.Search in Google Scholar

3. S. A. Sreenivas and K. V. Pai, Thiolated chitosans: Novel polymers for mucoadhesive drug delivery: A review, Trop. J. Pharm. Res. 7 (2008) 1077-1088.Search in Google Scholar

4. C. Valenta, The use of mucoadhesive polymers in vaginal delivery, Adv. Drug Deliv. Rev. 57 (2005) 1692-1712; DOI: 10.1016/j.addr.2005.07.004.10.1016/j.addr.2005.07.004Search in Google Scholar

5. S. Kawarkhe and S. S. Poddar, Designing of the mucoadhesive intravaginal spermicidal films, Indian J. Pharm. Sci. 72 (2010) 652-655; DOI: 10.4103/0250-474X.78540S.Search in Google Scholar

6. S. Roy, K. Pal, A. Anis, K. Pramanik and B. Prabhakar, Polymers in mucoadhesive drug delivery system: A brief note, Design Monom. Polym. 12 (2009) 483-495; DOI: 10.1163/138577209X12478 283327236.Search in Google Scholar

7. G. Sharma, S. Jain, A. K. Tiwary and G. Kaur, Once daily bioadhesive vaginal clotrimazole tablets: Design and evaluation, Acta Pharm. 56 (2006) 337-345.Search in Google Scholar

8. C. E. Kast, C. Valenta, M. Leopold and A. Bernkop-Schnürch, Design and in vitro evaluation of a novel bioadhesive vaginal drug delivery system for clotrimazole, J. Control. Release 81 (2002) 347-354; DOI: 10.1016/S0168-3659(02)00077-9.10.1016/S0168-3659(02)00077-9Search in Google Scholar

9. R. Vehring, W. R. Foss and L. David, Particle formation in spray drying, J. Aer. Sci. 38 (2007) 728-746; DOI: 10.1016/j.jaerosci.2007.04.005.10.1016/j.jaerosci.2007.04.005Search in Google Scholar

10. N. M. Ranjha, H. Khan and S. Naseem, Encapsulation and characterization of controlled release flurbiprofen loaded microspheres using bees wax as an encapsulating agent, J. Mater. Sci. Mater. Med. 21 (2010) 1621-1630; DOI: 10.1007/s10856-010-4034-4.10.1007/s10856-010-4034-420217193Search in Google Scholar

11. D. Perumal, C. M. Dangor, R. S. Alcock, N. Hurbons and K. R. Moopanar, Effect of formulation variables on in vitro drug release and micromeritic properties of modified release ibuprofen microspheres, J. Microencapsul. 16 (1996) 475-487.Search in Google Scholar

12. A. A. Kahtani and B. S. Sherigara, Controlled release of theophylline through semi-interpenetrating network microspheres of chitosan-(dextran-g-acrylamide), J. Mater. Sci. Mater. Med. 20 (2009) 1437-1445.10.1007/s10856-009-3704-619252971Search in Google Scholar

13. C. R. Palem, R. Gannu, S. K. Yamsani, V. V. Yamsani and M. R. Yamsani, Development of bioadhesive buccal tablets for felodipine and pioglitazone in combined dosage form: in vitro, exvivo, and in vivo characterization, Drug Deliv. 18 (2011) 344-352; DOI: 10.3109/10717544.2011. 557786.Search in Google Scholar

14. A. Madgulkar, S. Kadam and V. Pokharkar, Studies on formulation development of mucoadhesive sustained release itraconazole tablet using response surface methodology, AAPS PharmSciTech. 9 (2008) 998-1005; DOI: 10.1208/s12249-008-9119-8.10.1208/s12249-008-9119-8297704318770050Search in Google Scholar

15. United States Pharmacopoeia 30, National Formulary 25, USP Convention, Rockville (MD) 2007.Search in Google Scholar

16. Y. M. Rao, Design and evaluation of mucoadhesive drug delivery systems, Indian Drugs 35 (1998) 558-565. 371Search in Google Scholar

17. A. A. Dangi, N. R. Sheth, H. J. Patel, T. M. Shukla and H. M. Patel, Formulation and evaluation of once daily mucoadhesive vaginal tablet of clotrimazole using natural and synthetic polymers, Asian J. Pharm. Health Sci. 1 (2011) 176-182.Search in Google Scholar

18. B. Nath, L. K. Nath and P. Kumar, Preparation and in vitro dissolution profile of zidovudine loaded microspheres made of Eudragit RS 100, RL 100 and their combinations, Acta Pol. Pharm.68 (2011) 409-415.Search in Google Scholar

19. S. Maiti, S. Kaity, S. Ray and B. Sa, Development and evaluation of xanthan gum-facilitated ethyl cellulose microsponges for controlled percutaneous delivery of diclofenac sodium, ActaPharm. 61 (2011) 257-270; DOI: 10.2478/v10007-011-0022-6.10.2478/v10007-011-0022-621945905Search in Google Scholar

20. Y. Garg and K. Pathak, Design and in vitro performance evaluation of purified microparticles of pravastatin sodium for intestinal delivery, AAPS PharmSciTech. 12 (2011) 673-682; DOI: 10. 1208/s12249-011-9626-x. 10.1208/s12249-011-9626-x313467121594729Search in Google Scholar