<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Primary hepatic yolk sac tumour (YST) is an extremely rare tumour of the liver. The exact etiology of primary
hepatic YST is still unclear. This tumour is very aggressive with ability to spread into distant sites, where it can
lead to the first clinical presentation. The authors present a case of a 20-year-old woman with fever and pain in
the epigastrium, which later on moved to the right hypogastrium clinically resembling acute appendicitis.
Ultrasound revealed tumorous mass in the liver and hypoechogenous tumorous mass in the area of right adnexes
and terminal ileum. Tumorous mass in the liver was confirmed on the CT scan. Markedly raised levels of serum
α-fetoprotein concentration were detected. Laparoscopic appendectomy was performed and there was bioptically
verified a diagnosis of YST. Afterwards, patient underwent right hemihepatectomy, right hemicolectomy and right
adnexectomy. There was found no evidence of the gonadal, mediastinal, retroperitoneal and central nervous system
origin of the YST. Histological findings from the liver proved primary yolk sac tumour of the liver with the
metastatic spread into the appendix, caecum and regional lymph nodes.</p></abstract>

Primary hepatic yolk sac tumour (YST) is an extremely rare tumour of the liver. The exact etiology of primary
hepatic YST is still unclear. This tumour is very aggressive with ability to spread into distant sites, where it can
lead to the first clinical presentation. The authors present a case of a 20-year-old woman with fever and pain in
the epigastrium, which later on moved to the right hypogastrium clinically resembling acute appendicitis.
Ultrasound revealed tumorous mass in the liver and hypoechogenous tumorous mass in the area of right adnexes
and terminal ileum. Tumorous mass in the liver was confirmed on the CT scan. Markedly raised levels of serum
α-fetoprotein concentration were detected. Laparoscopic appendectomy was performed and there was bioptically
verified a diagnosis of YST. Afterwards, patient underwent right hemihepatectomy, right hemicolectomy and right
adnexectomy. There was found no evidence of the gonadal, mediastinal, retroperitoneal and central nervous system
origin of the YST. Histological findings from the liver proved primary yolk sac tumour of the liver with the
metastatic spread into the appendix, caecum and regional lymph nodes.

Primary yolk sac tumour of liver with unusual clinical presentation mimicking acute appendicitis

Clinic of Transplant and Vascular Surgery, Jessenius Faculty of Medicine in Martin, Comenius University and
University Hospital in Martin

2Clinic of Anesthesiology and Intensive Medicine, Jessenius Faculty of Medicine in
Martin, Comenius University and University Hospital in Martin

Department of Pathology of Slovak Medical
University and Oncologic Institute of St. Elizabeth, Bratislava, Slovak Republic

Acta Medica Martiniana

Primary hepatic yolk sac tumour (YST) is an extremely rare tumour of the liver. The exact etiology of primary
hepatic YST is still unclear. This tumour is very...

Primary yolk sac tumour of liver with unusual clinical presentation mimicking acute appendicitis

Published Online: Feb 25, 2014

Page range: 33 - 37

DOI: https://doi.org/10.2478/acm-2013-0021

Keywords
liver neoplasm, yolk sac tumour, endodermal sinus tumour, alpha-fetoprotein

This content is open access.

Primary yolk sac tumour of liver with unusual clinical presentation mimicking acute appendicitis

Published Online: Feb 25, 2014

Page range: 33 - 37

DOI: https://doi.org/10.2478/acm-2013-0021

Keywordsliver neoplasm, yolk sac tumour, endodermal sinus tumour, alpha-fetoprotein

This content is open access.

Keywords
liver neoplasm, yolk sac tumour, endodermal sinus tumour, alpha-fetoprotein