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<p>This paper provides a comprehensive overview of the microscopic landscape of the small intestinal epithelium, focusing on its general structure and the current state of knowledge regarding intestinal stem cells. The small intestine’s epithelial layer is intricately organized, comprising various cell types with specialized functions, including goblet cells, enterocytes, enteroendocrine cells, Paneth cells, microfold cells (M cells), and tuft cells. These cells collectively contribute to essential physiological processes such as digestion, absorption, and immune response regulation. The review delves into the role of intestinal stem cells, residing in the crypts, and their significance in maintaining tissue homeostasis and regeneration. Understanding the microscopic intricacies of the small intestinal epithelium is crucial for unraveling its physiological functions and exploring potential therapeutic avenues.</p>
</abstract>

This paper provides a comprehensive overview of the microscopic landscape of the small intestinal epithelium, focusing on its general structure and the current state of knowledge regarding intestinal stem cells. The small intestine’s epithelial layer is intricately organized, comprising various cell types with specialized functions, including goblet cells, enterocytes, enteroendocrine cells, Paneth cells, microfold cells (M cells), and tuft cells. These cells collectively contribute to essential physiological processes such as digestion, absorption, and immune response regulation. The review delves into the role of intestinal stem cells, residing in the crypts, and their significance in maintaining tissue homeostasis and regeneration. Understanding the microscopic intricacies of the small intestinal epithelium is crucial for unraveling its physiological functions and exploring potential therapeutic avenues.

Exploring the microscopic terrain of the small intestinal epithelium: a comprehensive overview of general architecture and the present understanding of intestinal stem cells

Division of Anatomy, Department of Human Morphology and Embryology

Medical Journal of Cell Biology

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

This paper provides a comprehensive overview of the microscopic landscape of the small intestinal epithelium, focusing on its general structure and the current...

Exploring the microscopic terrain of the small intestinal epithelium: a comprehensive overview of general architecture and the present understanding of intestinal stem cells

Published Online: Dec 31, 2023

Page range: 87 - 92

Received: Sep 18, 2023

Accepted: Oct 20, 2023

DOI: https://doi.org/10.2478/acb-2023-0015

Keywords
review, Lgr5+ cells, intestine epithelium

© 2023 Bernadetta Nowak et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Exploring the microscopic terrain of the small intestinal epithelium: a comprehensive overview of general architecture and the present understanding of intestinal stem cells

Published Online: Dec 31, 2023

Page range: 87 - 92

Received: Sep 18, 2023

Accepted: Oct 20, 2023

DOI: https://doi.org/10.2478/acb-2023-0015

Keywordsreview, Lgr5+ cells, intestine epithelium

© 2023 Bernadetta Nowak et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Keywords
review, Lgr5+ cells, intestine epithelium