<abstract xmlns="http://www.w3.org/1999/xhtml"><sec id="j_FON-2019-0045_s_006_w2aab3b7b7b1b6b1aab1c18b1Aa"><h3>Objective</h3><p>To compare the clinical efficacy between percutaneous vertebroplasty (PVP) and percutaneous kyphoplasty (PKP) in the treatment of Kümmell’s disease in Chinese patients.</p></sec><sec id="j_FON-2019-0045_s_007_w2aab3b7b7b1b6b1aab1c18b2Aa"><h3>Methods</h3><p>The studies using randomized controlled trials to compare clinical efficacy between PVP and PKP in the treatment of Kümmell’s disease in Chinese patients were retrieved from Embase, Pubmed, Central, Cinahl, PQDT, CNKI, CQVIP, Wanfang Data, and CBM (from September 2008 to September 2018). Keywords for both Chinese and English search were: percutaneous vertebroplasty, PVP, percutaneous kyphoplasty, PKP, and Kümmell’s disease. A total of 132 articles were retrieved based on the search strategy through online database searching and manual searching. Finally, one foreign report and seven Chinese reports were included. After extracting the data, statistical software Review Manager 5.3 was used for data analysis.</p></sec><sec id="j_FON-2019-0045_s_008_w2aab3b7b7b1b6b1aab1c18b3Aa"><h3>Results</h3><p>Through comparison, Cobb angle (95% CI [0.54, 4.42), <italic>P</italic> = 0.01] and Oswestry Dysfunction Index (ODI) (95% CI [0.21, 2.15], <italic>P</italic>= 0.02) of PKP group was smaller than that of PVP group. Postoperative anterior vertebral body height of the PKP group was better than PVP group (95% CI [−1.27, −0.66], <italic>P</italic> &lt; 0.001]. However, the PVP group had shorter operation time than PKP group (95% CI [−13.48, −7.43), <italic>P</italic> = 0.001]. In the other outcome measures, including Visual Analogue Scale (VAS) score (95% CI [−0.04, 0.27), <italic>P</italic> = 0.15), cement volume (95% CI [−0.82, 0.32], <italic>P</italic> = 0.39) and cement leakage (95% CI [0.90, 2.76], <italic>P</italic> = 0.11), there was no significant differences between the two procedures.</p></sec><sec id="j_FON-2019-0045_s_009_w2aab3b7b7b1b6b1aab1c18b4Aa"><h3>Conclusions</h3><p>At this stage, there is sufficient evidence to support that PKP is better than PVP in the treatment of Kümmell’s disease in Chinese patients. Although PVP surgery requires much less operation time, PKP has better postoperative radiological results and lower ODI. Moreover, both of them had similar clinical results (e.g., analgesic effects, cement dosage, and leakage rate). Further evidence is dependent on the emergence of randomized controlled trials with higher quality and larger sample sizes in the future.</p></sec></abstract>

ObjectiveTo compare the clinical efficacy between percutaneous vertebroplasty (PVP) and percutaneous kyphoplasty (PKP) in the treatment of Kümmell’s disease in Chinese patients.MethodsThe studies using randomized controlled trials to compare clinical efficacy between PVP and PKP in the treatment of Kümmell’s disease in Chinese patients were retrieved from Embase, Pubmed, Central, Cinahl, PQDT, CNKI, CQVIP, Wanfang Data, and CBM (from September 2008 to September 2018). Keywords for both Chinese and English search were: percutaneous vertebroplasty, PVP, percutaneous kyphoplasty, PKP, and Kümmell’s disease. A total of 132 articles were retrieved based on the search strategy through online database searching and manual searching. Finally, one foreign report and seven Chinese reports were included. After extracting the data, statistical software Review Manager 5.3 was used for data analysis.ResultsThrough comparison, Cobb angle (95% CI [0.54, 4.42), P = 0.01] and Oswestry Dysfunction Index (ODI) (95% CI [0.21, 2.15], P= 0.02) of PKP group was smaller than that of PVP group. Postoperative anterior vertebral body height of the PKP group was better than PVP group (95% CI [−1.27, −0.66], P < 0.001]. However, the PVP group had shorter operation time than PKP group (95% CI [−13.48, −7.43), P = 0.001]. In the other outcome measures, including Visual Analogue Scale (VAS) score (95% CI [−0.04, 0.27), P = 0.15), cement volume (95% CI [−0.82, 0.32], P = 0.39) and cement leakage (95% CI [0.90, 2.76], P = 0.11), there was no significant differences between the two procedures.ConclusionsAt this stage, there is sufficient evidence to support that PKP is better than PVP in the treatment of Kümmell’s disease in Chinese patients. Although PVP surgery requires much less operation time, PKP has better postoperative radiological results and lower ODI. Moreover, both of them had similar clinical results (e.g., analgesic effects, cement dosage, and leakage rate). Further evidence is dependent on the emergence of randomized controlled trials with higher quality and larger sample sizes in the future.

Percutaneous vertebroplasty versus percutaneous kyphoplasty for the treatment of delayed post-traumatic vertebral body collapse (Kümmell’s disease) in Chinese patients: a systematic review and meta-analysis

Frontiers of Nursing

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

ObjectiveTo compare the clinical efficacy between percutaneous vertebroplasty (PVP) and percutaneous kyphoplasty (PKP) in the treatment of Kümmell’s disease in...

Author	Study design	Group	Cases	Age (y)	Gender (M/F)	Outcomes	Newcastle-Ottawa Scale
Chen et al. 201215	Retrospective	PVP	33	69.2 ± 6.3	4/29	D, E, F, G	⋆⋆⋆⋆⋆
		PKP	30	68.7 ± 6.5	3/27

Feng and Sun	Retrospective	PVP	20	72.3 ± 5.4	12/28	A, B, C, D, E, F, G	⋆⋆⋆⋆⋆⋆
201816		PKP	20

Gao et al. 201617	Retrospective	PVP	38	73 ± 6	20/18	B, C, D, F	⋆⋆⋆⋆⋆
		PKP	35	75 ± 6	16/19

Li 201318	Retrospective	PVP	7	71.8 ± 7.69	3/4	A, C, D, F,	⋆⋆⋆⋆⋆⋆
		PKP	5		2/3

Shi et al. 201719	Retrospective	PVP	10	75.1 ± 3.6	7/16	A, B, C, D, E, G	⋆⋆⋆⋆⋆⋆
		PKP	13

Yu et al. 201620	Retrospective	PVP	14	74.47 ± 5.79	5/9	A, B, C, D, E, F	⋆⋆⋆⋆⋆⋆
		PKP	28	71.56 ± 8.35	9/16

Yu et al. 201621	Retrospective	PVP	48	74.6 (63–85)	10/38	A, B, C, D, E, F, G	⋆⋆⋆⋆⋆⋆
		PKP	20	75.9 (65–87)	4/16

Zhang et al. 201522	Retrospective	PVP	38	75.58 ± 4.97	10/28	B, D, E, F, G	⋆⋆⋆⋆⋆⋆
		PKP	35	73.74 ± 4.35	9/26

Percutaneous vertebroplasty versus percutaneous kyphoplasty for the treatment of delayed post-traumatic vertebral body collapse (Kümmell’s disease) in Chinese patients: a systematic review and meta-analysis

Article Category: Original article

Published Online: Dec 31, 2019

Page range: 273 - 283

Received: Jan 25, 2019

Accepted: Mar 06, 2018

DOI: https://doi.org/10.2478/FON-2019-0045

Keywords
Kümmell’s disease, percutaneous vertebroplasty, percutaneous kyphoplasty, post-trauma, vertebral body collapse, meta-analysis, systematic review

© 2019 Peng-Fei Han et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Figure 1

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Figure 6

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Figure 9

Figure 10

General characteristics of included studies.

Percutaneous vertebroplasty versus percutaneous kyphoplasty for the treatment of delayed post-traumatic vertebral body collapse (Kümmell’s disease) in Chinese patients: a systematic review and meta-analysis

Article Category: Original article

Published Online: Dec 31, 2019

Page range: 273 - 283

Received: Jan 25, 2019

Accepted: Mar 06, 2018

DOI: https://doi.org/10.2478/FON-2019-0045

KeywordsKümmell’s disease, percutaneous vertebroplasty, percutaneous kyphoplasty, post-trauma, vertebral body collapse, meta-analysis, systematic review

© 2019 Peng-Fei Han et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Figure 1

Figure 2

Figure 3

Figure 4

Figure 5

Figure 6

Figure 7

Figure 8

Figure 9

Figure 10

General characteristics of included studies.

Keywords
Kümmell’s disease, percutaneous vertebroplasty, percutaneous kyphoplasty, post-trauma, vertebral body collapse, meta-analysis, systematic review