<abstract xmlns="http://www.w3.org/1999/xhtml"><sec id="j_FON-2019-0038_s_006_w2aab3b7b1b1b6b1aab1c18b1Aa"><h3>Objective</h3><p>To summarize and evaluate the evidence of guidelines and systematic reviews (SRs) of nonpharmacological interventions for mild cognitive impairment (MCI) to support the development of future guidelines and clinical decisions for MCI patients.</p></sec><sec id="j_FON-2019-0038_s_007_w2aab3b7b1b1b6b1aab1c18b2Aa"><h3>Methods</h3><p>Scottish Intercollegiate Guideline Network (SIGN), National Institute for Health and Clinical Excellence (NICE), American Academy of Neurology (AAN), Registered Nurses Association of Ontario (RNAO), Web of Science, PubMed, Cochrane Library, CNAHL, VIP, China National Knowledge Infrastructure (CNKI), and Wanfang Database were searched for relevant publications, including guidelines and SRs, from January 2014 to March 2019. Two authors independently screened articles, extracted data, and assessed the publications for adherence to the inclusion criteria. Appraisal of Guidelines for Research and Evaluation (AGREE II) was used to assess the quality of the guidelines, and Assessment of Multiple Systematic Reviews (AMSTAR 2) was used to assess the quality of SRs. In addition, the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach was used to evaluate the quality of outcomes.</p></sec><sec id="j_FON-2019-0038_s_008_w2aab3b7b1b1b6b1aab1c18b3Aa"><h3>Results</h3><p>Thirty-two articles were retrieved, including 1 guideline and 31 SRs. Fourteen SRs of physical exercise for MCI, six articles describing cognitive interventions, four articles describing acupuncture, and seven articles assessing dietary interventions (including four articles employing a Mediterranean diet, one article using vitamin B supplementation, and two articles assessing the effects of tea, coffee, and caffeine) were included. The quality of the articles was very low for 4 (13%), low for 10 (32%), and moderate for 17 (55%).</p></sec><sec id="j_FON-2019-0038_s_009_w2aab3b7b1b1b6b1aab1c18b4Aa"><h3>Conclusions</h3><p>Based on the evidence available to date, nonpharmacological interventions may improve the current cognitive function of persons with MCI. In particular, physical exercise, cognitive interventions, and acupuncture exerted promising effects. However, due to the limited number and quality of the included publications, additional high-quality reviews are needed to further confirm.</p></sec></abstract>

ObjectiveTo summarize and evaluate the evidence of guidelines and systematic reviews (SRs) of nonpharmacological interventions for mild cognitive impairment (MCI) to support the development of future guidelines and clinical decisions for MCI patients.MethodsScottish Intercollegiate Guideline Network (SIGN), National Institute for Health and Clinical Excellence (NICE), American Academy of Neurology (AAN), Registered Nurses Association of Ontario (RNAO), Web of Science, PubMed, Cochrane Library, CNAHL, VIP, China National Knowledge Infrastructure (CNKI), and Wanfang Database were searched for relevant publications, including guidelines and SRs, from January 2014 to March 2019. Two authors independently screened articles, extracted data, and assessed the publications for adherence to the inclusion criteria. Appraisal of Guidelines for Research and Evaluation (AGREE II) was used to assess the quality of the guidelines, and Assessment of Multiple Systematic Reviews (AMSTAR 2) was used to assess the quality of SRs. In addition, the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach was used to evaluate the quality of outcomes.ResultsThirty-two articles were retrieved, including 1 guideline and 31 SRs. Fourteen SRs of physical exercise for MCI, six articles describing cognitive interventions, four articles describing acupuncture, and seven articles assessing dietary interventions (including four articles employing a Mediterranean diet, one article using vitamin B supplementation, and two articles assessing the effects of tea, coffee, and caffeine) were included. The quality of the articles was very low for 4 (13%), low for 10 (32%), and moderate for 17 (55%).ConclusionsBased on the evidence available to date, nonpharmacological interventions may improve the current cognitive function of persons with MCI. In particular, physical exercise, cognitive interventions, and acupuncture exerted promising effects. However, due to the limited number and quality of the included publications, additional high-quality reviews are needed to further confirm.

A summary of the evidence and evaluation of the effectiveness of nonpharmacological interventions for mild cognitive impairment

Frontiers of Nursing

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

ObjectiveTo summarize and evaluate the evidence of guidelines and systematic reviews (SRs) of nonpharmacological interventions for mild cognitive impairment...

A summary of the evidence and evaluation of the effectiveness of nonpharmacological interventions for mild cognitive impairment

Article Category: Original article

Published Online: Dec 31, 2019

Page range: 301 - 316

Received: Apr 22, 2019

Accepted: Jul 05, 2019

DOI: https://doi.org/10.2478/FON-2019-0038

Keywords
nonpharmacological intervention, mild cognitive impairment, systematic review methodology, evidence evaluation, evidence synthesis

© 2019 Zi-Meng Li et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

A summary of the evidence and evaluation of the effectiveness of nonpharmacological interventions for mild cognitive impairment

Article Category: Original article

Published Online: Dec 31, 2019

Page range: 301 - 316

Received: Apr 22, 2019

Accepted: Jul 05, 2019

DOI: https://doi.org/10.2478/FON-2019-0038

Keywordsnonpharmacological intervention, mild cognitive impairment, systematic review methodology, evidence evaluation, evidence synthesis

© 2019 Zi-Meng Li et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Keywords
nonpharmacological intervention, mild cognitive impairment, systematic review methodology, evidence evaluation, evidence synthesis