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Nifedipine Lowers Cocaine-Induced Brain and Liver Enzyme Activity and Cocaine Urinary Excretion in Rats


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Filip M, Frankowska M, Zaniewska M, Golda A, Przegalinski E. The serotonergic system and its role in cocaine addiction. Pharmacol Rep 2005;57:685-700.Search in Google Scholar

Mello NK, Mendelson JH. Cocaine, hormones and behavior: clinical and preclinical studies. In: Pfaff DW, Arnold AP, Etgen AM, Fahrbach SE, Rubin RT, editors. Hormones, brain and behavior. New York: Academic Press; 2002. p. 665-745.10.1016/B978-012532104-4/50106-2Search in Google Scholar

Vetulani J. Wapń i kanały wapniowe regulowane potencjałem [Calcium and voltage-dependent calcium channels, in Polish]. Kosmos 1997;46:491-505.Search in Google Scholar

Pasternak GW, Kolesnikov YA, Babey AM. Perspectives on the N-methyl-D-aspartate/nitric oxide (NMDA/NO) cascade and opioid tolerance. Neuropsychopharmacology 1995;13:309-13.10.1016/0893-133X(95)00084-QSearch in Google Scholar

Vitcheva V, Mitcheva M. Effects of nifedipine on behavioral and biochemical parameters in rats after multiple morphine administration. Methods Find Exp Clin Pharmacol 2004;26:631-4.10.1358/mf.2004.26.8.863729Search in Google Scholar

Vitcheva V, Karova D, Mitcheva M. Influence of nifedipine on morphine elimination after multiple administration in rats. In: Tonev S, Kanev K, Dishovsky C, editors. Medical management of chemical and biological casualties. Sofia: Publishing house IRITA; 2009. p. 274-80.10.1016/j.toxlet.2009.06.362Search in Google Scholar

Drocourt L, Pascussi JM, Assenat E, Fabre JM, Maurel P, Vilarem MJ. Calcium channel modulators of the dihydropyridine family are human pregnane X receptor activators and inducers of CYP 3A, CYP 2B and CYP 2C in human hepatocytes. Drug Metab Dispos 2001;29:1325-31.Search in Google Scholar

Sun L, Lau CE. Simultaneous pharmacokinetic modeling of cocaine and its metabolites, norcocaine and benzoylecgonine, after intravenous and oral administration in rats. Drug Metab Dispos 2001;29:1183-9.Search in Google Scholar

Shuster L, Garhart C, Powers J, Grunfeld Y, Kanel G. Hepatotoxicity of cocaine. In: Clouet D, Asghar K, Brown R, editors. Mechanisms of cocaine abuse and toxicity. NIDA Research Monograph 88. Rockville (MD): National Institute on Drug Abuse; 1988. p. 250-75.10.1037/e496572006-015Search in Google Scholar

Powers JF, Shuster L. Subacute cocaine treatment changes expression of mouse liver cytochrome P450 isoforms. Pharmacology 1999;58:87-100.10.1159/000028271Search in Google Scholar

Pasanen M, Pellinen P, Stenbäck F, Juvonen RO, Raunio H, Pelkonen O. The role of CYP enzymes in cocaine-induced liver damage. Arch Toxicol 1995;69:287-90.10.1007/s002040050172Search in Google Scholar

Vitcheva V, Mitcheva M. Changes in liver and brain cytochrome P450 after multiple administration of cocaine, alone and in combination with nifedipine. Arh Hig Rada Toksikol 2007;58:287-91.10.2478/v10004-007-0019-1Search in Google Scholar

Amacher DE, Schomaker SJ. Ethylmorphine N-demethylase activity as a marker for cytochrome P450 CYP 3A activity in rat hepatic microsomes. Toxicol Lett 1998;94:115-25.10.1016/S0378-4274(97)00108-2Search in Google Scholar

Monostory K, Hazai E, Vereczkey L. Inhibition of cytochrome P450 enzymes participating in p-nitrophenol hydroxilation by drugs known as CYP 2E1 inhibitors. Chem Biol Interact 2004;147:331-40.10.1016/j.cbi.2004.03.00315135088Search in Google Scholar

Morishima HO, Abe Y, Matsuo M, Akiba K, Masaoko T, Cooper TB. Gender-related differences in cocaine toxicity in the rat. J Lab Clin Med 1993;122:157-63.Search in Google Scholar

Whittington RA, Iso A, Khan K, Cooper TB, Morishima HO. Role of gender in the toxicity of norcocaine. J Lab Clin Med 1999;133:590-6.10.1016/S0022-2143(99)90189-0Search in Google Scholar

Council of Europe. European Convention for the Protection of Vertebrate Animals used for Experimental and other Scientific Purposes. CETS No. 123, 1991. [displayed 30 May 2007] Available at http://conventions.coe.int/Treaty/Commun/QueVoulezVous.asp?NT=123&CM=8&DF=31/03/2011&CL=ENGSearch in Google Scholar

Antkiewicz-Michaluk L, Románska I, Vetulani J. Ca2+ channel blockade prevents lysergic acid diethylamide-induced changes in dopamine and serotonin metabolism. Eur J Pharmacol 1997;332:9-14.10.1016/S0014-2999(97)01025-XSearch in Google Scholar

Itzhak Y, Ali SF, Martin JL, Black MD, Huang PL. Resistance of neuronal nitric oxide synthase-deficient mice to cocaineinduced locomotor sensitization. Psychopharmacol 1998;140:378-86.10.1007/s002130050779Search in Google Scholar

Knowles RG, Moncada S. Nitric oxide synthases in mammals. Biochem J 1994;298:249-58.10.1042/bj2980249Search in Google Scholar

Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the Folin phenol reagent. J Biol Chem 1951;193:265-75.10.1016/S0021-9258(19)52451-6Search in Google Scholar

Guengerich FP. Microsomal enzymes involved in toxicology. Analysis and separation. In: Heis AW editor. Principals and methods of toxicology. New York (NY): Raven Press; 1987. p. 609-34.Search in Google Scholar

Nash T. The colorimetric estimation of formaldehyde by means of the Hantzsch reaction. Biochem J 1953;55:416-21.10.1042/bj0550416Search in Google Scholar

Mazel P. Experiments illustrating drug metabolism in vitro - determination of microsomal anyline hydroxilase. In: La Du BN, Mandel HG, Way EL, editors. Fundamentals of drug metabolism and drug disposition. Wilkins, Baltimore; 1971. p. 546.Search in Google Scholar

Omura T, Sato R. The carbon monoxide-binding pigment of liver microsomes. J Biol Chem 1964;239:2370-85.10.1016/S0021-9258(20)82244-3Search in Google Scholar

Bump EA, Taylor YC, Brown MJ. Role of glutathione in the hypoxic cell cytotoxicity of misonidazole. Cancer Res 1983;43:997-1002.Search in Google Scholar

Bashkatova V, Meunier J, Vanin A, Maurice T. Nitric oxide and oxidative stress in the brain of rats exposed in utero to cocaine. Ann NY Acad Sci 2006;1074:632-42.10.1196/annals.1369.06117105958Search in Google Scholar

Vetulani J. Drug addiction. Part III. Pharmacotherapy of addiction. Pol J Pharmacol 2001;53:415-35.Search in Google Scholar

Nasif FJ, Hu XT, White FJ. Repeated cocaine administration increases voltage-sensitive calcium currents in response to membrane depolarization in medial prefrontal cortex pyramidal neurons. J Neurosci 2005;25:3674-9.10.1523/JNEUROSCI.0010-05.2005672538315814798Search in Google Scholar

Konno Y, Sekimoto M, Nemoto K, Degawa M. Sex difference in induction of hepatic CYP2B and CYP3A subfamily enzymes bynicardipine and nifedipine in rats. Toxicol Appl Pharmacol 2004;196:20-8.10.1016/j.taap.2003.12.00915050404Search in Google Scholar

Cui X, Thomas A, Han Y, Palamanda J, Montgomery D, White RE, Morrison RA, Cheng KC. Quantitative PCR assay for cytochromes P450 2B and 3A induction in rat precisioncut liver slices: correlation study with induction in vivo. J Pharmacol Toxicol Methods 2005;52:234-43.10.1016/j.vascn.2005.02.001Search in Google Scholar

Iwamoto IM, Moore CM, Fujiwara N, Christ MJ, Gries DM, Nakamura KT. m-hydroxy benzoylecgonine recovery in fetal guinea pigs. Drug Metab Dispos 2000;28:335-8.Search in Google Scholar

Ladona MG, Gonzalez mL, Rane A, Peter RM, de la Torre R. Cocaine metabolism in human fetal and adult liver microsomes is related to cytochrome P450 3A expression. Life Sci 2000;68:431-43.10.1016/S0024-3205(00)00952-8Search in Google Scholar

Arinc E, Bozcaarmutlu A. Catalyzation of cocaine N-demethylation by cytochromes P4502B, P4503A, and P4502D in fish liver. J Biochem Mol Toxicol 2003;17:169-76.10.1002/jbt.10075Search in Google Scholar

Yu RCT, Lee TC, Wang TC, Li JH. Genetic toxicity of cocaine. Carcinogenesis 1999;20:1193-9.10.1093/carcin/20.7.1193Search in Google Scholar

Mazumder PK, Suqendran K, Vijayaraghavan R. Protective efficacy of calcium channel blockers in sulphur mustard poisoning. Biomed Environ Sci 1978;11:363-9.Search in Google Scholar

Rofael HZ, Abdel-Rahman MS. The role of ketamine on plasma cocaine pharmacokinetics in rat. Toxicol Let 2002;129:167-76.10.1016/S0378-4274(02)00008-5Search in Google Scholar

Nayak PK, Misra AL, Mulé SJ. Physiological disposition and biotransformation of (3H) cocaine in acutely and chronically treated rats. Pharmacol Exp Ther 1976;196:556-69.Search in Google Scholar

ISSN:
0004-1254
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Medicine, Basic Medical Science, other