[Singh NP, Lai H, Khan A. Ethanol-induced single-strand DNA breaks in rat brain cells. Mutat Res 1995;345:191-6.10.1016/0165-1218(95)90054-3]Search in Google Scholar
[Barret L, Soubeyran A, Usson Y, Eysseric H, Saxod R. Characterization of the morphological variations of astrocytes in culture following ethanol exposure. Neurotoxicology 1996;17:497-507.]Search in Google Scholar
[Lamarche F, Gonthier B, Signorini N, Eysseric H, Barret L. Acute exposure of cultured neurones to ethanol results in reversible DNA single-strand breaks; whereas chronic exposure causes loss of cell viability. Alcohol Alcohol 2003;38:550-8.10.1093/alcalc/agg118]Search in Google Scholar
[Mattson SN, Schoenfeld AM, Riley EP. Teratogenic effects of alcohol on brain and behavior. Alcohol Res Health 2001;25(Suppl 3):185-91.]Search in Google Scholar
[Kimelberg HK, Norenberg MD. Astocytes. Sci Am 1989;260:66-76.10.1038/scientificamerican0489-66]Search in Google Scholar
[Di Monte DA, Royland JE, Irwin I, Langston JW. Astrocytes as the site for bioactivation of neurotoxins. Neurotoxicology 1996;17:697-703.]Search in Google Scholar
[Ledig M, Megias-Megias L, Tholey G. Maternal alcohol exposure before and during pregnancy: effect on development of neurons and glial cells in culture. Alcohol Alcohol 1991;26:169-76.10.1093/oxfordjournals.alcalc.a045098]Search in Google Scholar
[Ledig M, Tholey G, Megias-Megias L, Kopp P, Wedler F. Combined effects of ethanol and manganese on cultured neurons and glia. Neurochem Res 1991;16:591-6.10.1007/BF00974879]Search in Google Scholar
[Holownia A, Ledig M, Copin JC, Tholey G. The effect of ethanol on HSP70 in cultured rat glial cells and in brain areas of rat pups exposed to ethanol in utero. Neurochem Res 1995;20:875-8.10.1007/BF00969701]Search in Google Scholar
[Holownia A, Ledig M, Mapoles J, Ménez JF. Acetaldehyde-induced growth inhibition in cultured rat astroglial cells. Alcohol 1996;13:93-7.10.1016/0741-8329(95)02019-5]Search in Google Scholar
[Holownia A, Ledig M, Ménez JF. Ethanol-induced cell death in cultured rat astroglia. Neuro-Toxicol Teratol 1997;19:141-6.10.1016/S0892-0362(96)00226-7]Search in Google Scholar
[Quertemont E, Tambour S, Bernaerts P, Zimatkin SM, Tirelli E. Behavioral characterization of acetaldehyde in C57BL/6J mice: locomotor, hypnotic, anxiolytic and amnesic effects. Psychopharmacology (Berl) 2004;177:84-92.10.1007/s00213-004-1911-x15160264]Search in Google Scholar
[Deitrich RA. Acetaldehyde: déjà vu du jour. J Stud Alcohol 2004;65:557-72.10.15288/jsa.2004.65.55715536764]Search in Google Scholar
[Luke Y Ethanol. In: Goldfrank LR, Flomenbaum NE, Lewin NA, Howland MA, Hoffman RS, Nelson LS, editors. Goldfrank's Toxicologic Emergencies. 7th ed. New York (NY): McGraw-Hill; 2002. p. 1147-61.]Search in Google Scholar
[Zimatkin SM, Dietrich RA. Ethanol metabolism in the brain. Addict Biol 1997;2:387-413.10.1080/13556219772444]Search in Google Scholar
[Hunt WA. Role of acetaldehyde in the actions of ethanol on the brain - a review. Alcohol 1996;13:147-51.10.1016/0741-8329(95)02026-8]Search in Google Scholar
[Aragon CM, Rogan F, Amit Z. Studies on ethanol-brain catalase interaction: evidence for central ethanol oxidation. Alcoh Clin Exp Res 1991;15:165-9.10.1111/j.1530-0277.1991.tb01848.x]Search in Google Scholar
[Gill K, Menez JF, Lucas D, Deitrich RA. Enzymatic production of acetaldehyde from ethanol in rat brain tissue. Alcohol Clin Exp Res 1992;16:910-5.10.1111/j.1530-0277.1992.tb01892.x]Search in Google Scholar
[Aragon CM, Amit Z. Differences in ethanol-induced behaviors in normal and acatalasemic mice: systematic examination using a biobehavioral approach. Pharmacol Biochem Behav 1993;44:547-54.10.1016/0091-3057(93)90165-P]Search in Google Scholar
[Zimatkin SM, Buben AL. Ethanol oxidation in the living brain. Alcohol Alcohol 2007;42:529-32.10.1093/alcalc/agm059]Search in Google Scholar
[Zimatkin SM, Lindros KO. Distribution of catalase in rat brain: aminergic neurons as possible targets for ethanol effects. Alcohol Alcohol 1996;31:167-74.10.1093/oxfordjournals.alcalc.a008128]Search in Google Scholar
[Quertemont E, Eriksson CJ, Zimatkin SM, Pronko PS, Diana M, Pisano M, Rodd ZA, Bell RR, Ward RJ. Is ethanol a prodrug? Acetaldehyde contribution to brain ethanol effects. Alcohol Clin Exp Res 2005;29:1514-21.10.1097/01.alc.0000175015.51329.45]Search in Google Scholar
[Aragon CM, Spivak K, Amit Z. Effect of 3-amino-1,2,4-triazole on ethanol-induced narcosis, lethality and hypothermia in rats. Pharmacol Biochem Behav 1991;39:55-9.10.1016/0091-3057(91)90397-K]Search in Google Scholar
[Aragon CM, Amit Z. The effect of 3-amino-1,2,4-triazole on voluntary ethanol consumption: evidence for brain catalase involvement in the mechanism of action. Neuropharmacology 1992;31:709-12.10.1016/0028-3908(92)90150-N]Search in Google Scholar
[Aragon CM, Spivak K, Amit Z. Blockade of ethanol induced conditioned taste aversion by 3-amino-1,2,4-triazole: evidence for catalase mediated synthesis of acetaldehyde in rat brain. Life Sci 1985;37:2077-84.10.1016/0024-3205(85)90579-X]Search in Google Scholar
[Tampier L, Quintanilla ME. Effect of 3-amino-1,2,4-triazole on the hypothermic effect of ethanol and on ethanol tolerance development. Alcohol 1991;8:279-82.10.1016/0741-8329(91)90369-8]Search in Google Scholar
[Wilson JX. Antioxidant defense of the brain: a role for astrocytes. Can J Pharmacol 1997;75:1149-63.10.1139/y97-146]Search in Google Scholar
[Pentreath VW, Slamon ND. Astrocyte phenotype and prevention against oxidative damage in neurotoxicity. Hum Exp Toxicol 2000;19:641-9.10.1191/096032700676221595]Search in Google Scholar
[Lipnik-Stangelj M, Carman-Krzan M. Activation of histamine H1-receptor enhances neurotrophic factor secretion from cultured astrocytes. Inflamm Res 2004;53:245-52.10.1007/s00011-004-1247-3]Search in Google Scholar
[Uliasz TF, Hewett SJ. A microtiter trypan blue absorbance assay for the quantitative determination of excitotoxic neuronal injury in cell culture. J Neurosci Methods 2000;100:157-63.10.1016/S0165-0270(00)00248-X]Search in Google Scholar
[Protocol online. Your lab's reference book [displayed 21 April 2009]. Available at http://www.protocol-online.org/prot/Image_Techniques/Microscopy/Light_Microscopy/index.html]Search in Google Scholar
[Bradford M. A rapid and sensitive method for quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976;72:248-54.10.1016/0003-2697(76)90527-3]Search in Google Scholar
[Forn-Frías C, Sanchis-Segura C. The possible role of acetaldehyde in the brain damage caused by the chronic consumption of alcohol. Rev Neurol 2003;37:485-93.]Search in Google Scholar
[Davies DL, Cox WE. Delayed growth and maturation of astrocytic cultures following exposure to ethanol: electron microscopic observations. Brain Res 1991;546:53-61.]Search in Google Scholar
[Guizzeti M, Costa LG. Inhibition of muscarinic receptor-stimulated glial cell proliferation by ethanol. J Neurochem 1996;67:2236-45.10.1046/j.1471-4159.1996.67062236.x]Search in Google Scholar
[Russo A, Palumbo M, Scifo C, Cardile V, Barcellona mL, Renis M. Ethanol-induced oxidative stress in rat astrocytes: role of hsp70. Cell Biol Toxicol 2001;17:153-68.10.1023/A:1011936313510]Search in Google Scholar
[Muscoli C, Fresta M, Cardile V, Palumbo M, Renis M, Puglisi G, Paolino D, Nisticò, S, Rotiroti D, Mollace V. Ethanol-induced injury in rat primary cortical astrocytes involves oxidative stress: effect of idebenone. Neurosci Lett 2002;329:21-4.10.1016/S0304-3940(02)00567-0]Search in Google Scholar
[Gonthier B, Signorini-Allibe N, Soubeyran A, Eysseric H, Lamarche F, Barret L. Ethanol can modify the effects of certain free radical-generating systems on astrocytes. Alcohol Clin Exp Res 2004;28:526-34.10.1097/01.ALC.0000122271.32522.A7]Search in Google Scholar
[Signorini-Allibe N, Gonthier B, Lamarche F, Eysseric H, Barret L. Chronic consumption of ethanol leads to substantial cell damage in cultured rat astrocytes in conditions promoting acetaldehyde accumulation. Alcohol Alcohol 2004;40:163-71.10.1093/alcalc/agh097]Search in Google Scholar
[Rottenberg H. Membrane solubility of ethanol in chronic alcoholism. The effect of ethanol feeding and its withdrawal on the protection by alcohol of rat red blood cells from hypotonic hemolysis. Biochim Biophys Acta 1986;855:211-22.10.1016/0005-2736(86)90167-7]Search in Google Scholar
[O'Callaghan JP, Jensen KF, Miller DB. Quantitative aspects of drug and toxicant induced astrogliosis. Neurochem Int 1995;26:115-24.10.1016/0197-0186(94)00106-5]Search in Google Scholar
[Wilson JX. Antioxidant defense of the brain: a role for astrocytes. Can J Physiol Pharmacol 1997;75:1149-63.10.1139/y97-146]Search in Google Scholar
[Watts LT, Rathinam ML, Schenker S, Henderson GI. Astrocytes protect neurons from ethanol-induced oxidative stress and apoptotic death. J Neurosci Res 2005;80:655-66.10.1002/jnr.20502]Search in Google Scholar
[Poisindex, [CD-ROM]. Greenwood Village, USA: Thompson Micromedex; 2008.]Search in Google Scholar
[Labourdette G, Sensenbrenner M. Growth factors and their receptors in the central nervous system. In: Kettenmann H, Ranson BR, editors. Neuroglia. New York (NY): Oxford University Press; 1995. p. 441-59.]Search in Google Scholar
[Lauder JM. Neurotransmitters as growth regulatory signals: role of receptors and second messengers. Trends Neurosci 1993;16:233-40.10.1016/0166-2236(93)90162-F]Search in Google Scholar
[Resnicoff M, Rubini M, Baserga R, Rubin R. Ethanol inhibits insulin-like growth factor-1-mediated signalling and proliferation of C6 rat glioblastoma cells. Lab Invest 1994;71:657-62.]Search in Google Scholar
[Luo J, Miller MW., Growth factor-mediated neural proliferation: target of ethanol toxicity. Brain Res Brain Res Rev 1998;27:157-67.10.1016/S0165-0173(98)00009-5]Search in Google Scholar
[Guerri C, Sáez R, Sancho-Tello M, Martin de Aquilera E, Renau-Piqueras J. Ethanol alters astrocyte development: a study of critical periods using primary cultures. Neurochem Res 1990;15:559-65.10.1007/BF00966217]Search in Google Scholar
[Holownia A, Ledig M, Braszko JJ, Ménez JF. Acetaldehyde cytotoxicity in cultured rat astrocytes. Brain Res 1999;833:202-8.10.1016/S0006-8993(99)01529-2]Search in Google Scholar
[Eysseric H, Gonthier B, Soubeyran A, Richard MJ, Daveloose D, Barret L. Effects of chronic ethanol exposure on acetaldehyde and free radical production by astrocytes in culture. Alcohol 2000;21:117-25.10.1016/S0741-8329(00)00075-6]Search in Google Scholar