Dawson RM. Review of oximes available for the treatment of nerve agent poisoning. J Appl Toxicol 1994;14:317-31.10.1002/jat.2550140502Search in Google Scholar

Johnson MK, Jacobsen D, Meredith TJ, Eyer P, Heath AJ, Ligtenstein DA, Marrs TC, Szinicz L, Vale JA, Haines JA. Evaluation of antidotes for poisoning by organophosphorus pesticides. Emerg Med 2000;12:22-37.10.1046/j.1442-2026.2000.00087.xSearch in Google Scholar

Sheridan RD, Beeson D, Tattersall JEH. Non-competitive block of the human muscle adult nicotinic acetylcholine receptor ion channel by the bispyridinium compounds, SAD-128 (SAD), toxogonin (TOX) and HI-6. Eur J Neurosci 2000;12(Suppl. S):36.Search in Google Scholar

Stojiljković MP, Jokanović M. Pyridinium oximes: rationale for their selection as causal antidotes against organophosphate poisonings and current solutions for auto-injectors. Arh Hig Rada Toksikol 2006;57:435-43.Search in Google Scholar

Shih TM, Koviak TA, Capacio BR. Anticonvulsants for poisoning by the organophosphorus compound soman: Pharmacological mechanisms. Neurosci Biobehav Rev 1991;15:349-62.10.1016/S0149-7634(05)80028-4Search in Google Scholar

Shih TM, McDonough JH, Koplovitz I. Anticonvulsants for soman-induced seizure activity. J Biomed Sci 1999;6:86-96.10.1007/BF02256439Search in Google Scholar

Thiermann H, Szinicz L, Eyer P, Felgenhauer N, Zilker T, Worek F. Lessons to be learnt from organophosphorus pesticide poisoning for the treatment of nerve agent poisoning. Toxicology 2007;233:145-54.10.1016/j.tox.2006.11.056Search in Google Scholar

Thiermann H, Szinicz L, Eyer F, Worek F, Eyer P, Felgenhauer N, Zilker T. Modern strategies in therapy of organophosphate poisoning. Toxicol Lett 1999;107:233-9.10.1016/S0378-4274(99)00052-1Search in Google Scholar

Eto M. Organic and biological chemistry. In: Zweig G, editor. The Organophosphorus Pesticides. Cleveland: CRC Press Inc.; 1976. p. 142.Search in Google Scholar

Hamilton MG, Lundy PM. HI-6 therapy of soman and tabun poisoning in primates and rodents. Arch Toxicol 1989;63:144-9.10.1007/BF00316437Search in Google Scholar

Maksimović M, Bošković B, Radović L, Tadić V, Deljac V, Binenfeld Z. Antidotal effects of bis-pyridinium-2-monooxime carbonyl derivatives in intoxications with highly toxic organophosphorus compounds. Acta Pharm Jugoslav 1980;30:151-60.Search in Google Scholar

Jokanović M, Maksimović M, Kilibarda V, Jovanović D, Savić D. Oxime-induced reactivation of acetylcholinesterase inhibited by phosphoramidates. Toxicol Lett 1996;85:35-9.10.1016/0378-4274(96)03634-XSearch in Google Scholar

Čalić M, Lucić Vrdoljak A, Radić B, Jelić D, Jun D, Kuča K, Kovarik Z. In vitro and in vivo evaluation of pyridinium oximes: Mode of interaction with acetylcholinesterase, effect on tabun- and soman-poisoned mice and their cytotoxicity. Toxicology 2006;219:85-96.10.1016/j.tox.2005.11.00316332406Search in Google Scholar

Lucić Vrdoljak A, Čalić M, Radić B, Berend S, Jun D, Kuča K, Kovarik Z. Pretreatment with pyridinium oximes improves antidotal therapy against tabun poisoning. Toxicology 2006;228:41-50.10.1016/j.tox.2006.08.01216982122Search in Google Scholar

Kovarik Z, Čalić M, Bosak A, Šinko G, Jelić D. In vitro evaluation of aldoxime interactions with human acetylcholinesterase. Croat Chem Acta 2008;81:47-57.Search in Google Scholar

Kovarik Z, Čalić M, Šinko G, Bosak A, Berend S, Lucić Vrdoljak A, Radić B. Oximes: Reactivators of phosphorylated acetylcholinesterase and antidotes in therapy against tabun poisoning. Chem Biol Interact 2008;175:173-9.10.1016/j.cbi.2008.04.011Search in Google Scholar

Berend S, Lucić Vrdoljak A, Radić B, Kuča K. New bispyridinium oximes: In vitro and in vivo evaluation of their biological efficiency in soman and tabun poisoning. Chem Biol Interact 2008;175:413-6.10.1016/j.cbi.2008.04.031Search in Google Scholar

Čalić M, Bosak A, Kuča K, Kovarik Z. Interactions of butane, but-2-ene or xylene-like linked bispyridinium para-aldoximes with native and tabun-inhibited human cholinesterases. Chem Biol Interact 2008;175:305-8.10.1016/j.cbi.2008.04.010Search in Google Scholar

Musilek K, Jun D, Cabal J, Kassa J, Gunn-Moore F, Kuca K. Design of a potent reactivator of tabun-inhibited acetylcholinesterase-synthesis and evaluation of (E)-1-(4-carbamoylpyridinium)-4-(4-hydroxyi-minomethylpyridinium)-but-2-ene dibromide (K203). J Med Chem 2007;50:5514-8.10.1021/jm070653rSearch in Google Scholar

Kovarik Z, Čalić M, Šinko G, Bosak A. Structure-activity approach in the reactivation of tabun-phosphorylated human acetylcholinesterase with bispyridinium para-oximes. Arh Hig Rada Toksikol 2007;58:201-9.10.2478/v10004-007-0013-7Search in Google Scholar

Šinko G, Čalić M, Kovarik Z. para- and ortho-Pyridinium aldoximes in reaction with acetylcholinesterase. FEBS Letters 2006;580:3167-72.10.1016/j.febslet.2006.04.070Search in Google Scholar

Šinko G, Čalić M, Bosak A, Kovarik Z. Limitation of the Ellman method: Cholinesterase activity measurement in the presence of oximes. Anal Biochem 2007;370:223-7.10.1016/j.ab.2007.07.023Search in Google Scholar

Thompson WR. Use of moving averages and interpolation to estimate median effective dose. Bacteriol Rev 1947;11:115-45.10.1128/br.11.2.115-145.1947Search in Google Scholar

Weil CS. Tables for convenient calculation of median-effective dose (LD50 or ED50) and instruction in their use. Biometrics 1952;8:249-63.10.2307/3001557Search in Google Scholar

Ellman GL, Courtney KD, Andres VJ, Featherstone RM. A new and rapid colorimetric determination of acetylcholinesterase activity. Biochem Pharmacol 1960;7:88-95.10.1016/0006-2952(61)90145-9Search in Google Scholar

Thiermann H, Mast U, Klimmek R, Eyer P, Hibler A, Pfab R, Flegenhauer N, Zilker T. Cholinesterase status, pharmacokinetics and laboratory findings during obidoxime therapy in organophosphate poisoned patients. Hum Exp Toxicol 1997;16:473-80.10.1177/0960327197016008099292288Search in Google Scholar

Eddleston M, Szinicz L, Eyer P, Buckley N. Oximes in acute organophosphorus pesticide poisoning: a systemic review of clinical trials. Qjm-Mon J Assoc Phys 2002;95:275-83.10.1093/qjmed/95.5.275147592211978898Search in Google Scholar

Kalász H, Hasan MY, Sheen R, Kuča K, Petroianu G, Ludányi K, Gergely A, Tekes K. HPLC analysis of K-48 concentration in plasma. Anal Bioanal Chem 2006;385:1062-7.10.1007/s00216-006-0490-616763789Search in Google Scholar

eISSN:
0004-1254
Languages:
English, Slovenian
Publication timeframe:
4 times per year
Journal Subjects:
Medicine, Basic Medical Science, other