About this article
Article Category: Clinical Practice
Published Online: Jun 28, 2018
Page range: 50 - 65
DOI: https://doi.org/10.17225/jhp00112
Keywords
© 2018 Laura Savini, Radoslaw Kaczmarek, Declan Noone, Paul Giangrande, Geoffrey Dusheiko, Brian O’Mahony, published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Figure 1
Figure A1
Frequency of testing of progression of liver disease
| EVERY SIX MONTHS | ANNUALLY | EVERY TWO YEARS | NOT TESTED ROUTINELY |
|---|---|---|---|
| Albania | Czech Republic | Cyprus | Austria |
| France | Denmark | Finland | Belarus |
| Germany | Italy | The Netherlands | Poland |
| Hungary | Latvia | Ukraine | |
| Ireland | Lithuania | ||
| Portugal | Macedonia | ||
| Slovakia | Sweden | ||
| Slovenia |
Availability of treatment products and level of reimbursement
| PEG- INTERFERON +RIBAVIRIN | PEG-INTERFERON +RIBAVIRIN+ TELAPREVIR/ BOCEPREVIR | PEG-INTERFERON +RIBAVIRIN +SOFOSBUVIR | SECOND GENERATION DAAS sofosbuvir, velpatasvir, elbasvir, grazoprevir, daclatasvir, ombitasvir, paritaprevir+ritonavir, dasabuvir, ledipasvir | |
|---|---|---|---|---|
| Is available in my country and it is fully covered by the national healthcare system | 24 | 7 | 17 | 19 |
| Is available in my country and the patient needs to partially pay for this treatment | 2 | 0 | 0 | 1 |
| Is available in my country but the patient needs to fully pay for its treatment | 0 | 11 | 3 | 1 |
| Is not available in my country | 0 | 2 | 1 | 3 |
| No data | 4 | 10 | 9 | 6 |
Countries providing exact figures, estimates or no data on PWBD who remain to be successfully treated, had a liver transplant, developed hepatocellular carcinoma (HCC) and have been financially compensated (question 7)
| COUNTRY | REMAIN TO BE TREATED SUCCESSFULLY | HAD A LIVER TRANSPLANT | DEVELOPED HCC | HAVE BEEN FINANCIALLY COMPENSATED |
|---|---|---|---|---|
| Albania | Est. | ND | ND | Est. |
| Austria | ND | ND | ND | ND |
| Azerbaijan | ND | ND | ND | ND |
| Belarus | Est. | ND | ND | ND |
| Bosnia & Herzegovina | ND | ND | ND | ND |
| Bulgaria | Exact | ND | ND | ND |
| Cyprus | Est. | Exact | Exact | Exact |
| Czech Republic | Exact | Est. | Est. | Est. |
| Denmark | Est. | ND | ND | Exact |
| Finland | Exact | Exact | ND | ND |
| France | Est. | Exact | Exact | Exact |
| Germany | Exact | Exact | Exact | Exact |
| Greece | Est. | Est. | Est. | Exact |
| Hungary | Est. | Exact | Exact | Exact |
| Ireland | Exact | Exact | Est. | Exact |
| Italy | Est. | Est. | ND | Est. |
| Latvia | ND | ND | ND | ND |
| Lithuania | Est. | Exact | Exact | ND |
| Macedonia | ND | ND | ND | Exact |
| Montenegro | Exact | Exact | Exact | Exact |
| The Netherlands | ND | ND | ND | Exact |
| Poland | ND | ND | ND | Exact |
| Portugal | Exact | Est. | Est. | Exact |
| Romania | ND | ND | ND | ND |
| Slovakia | Exact | Exact | Exact | Exact |
| Slovenia | Exact | Exact | Exact | Exact |
| Sweden | Exact | ND | ND | Exact |
| Switzerland | ND | ND | ND | ND |
| Ukraine | Est. | Exact | ND | ND |
| United Kingdom | ND | ND | ND | Est. |
Countries providing exact figures, estimates or no data on spontaneous HCV clearance/SVR (question 6)
| COUNTRY | SPONTANEOUS CLEARANCE | SVR | SVR WITH SECOND-GENERATION DAAS |
|---|---|---|---|
| Albania | ND | ND | ND |
| Austria | ND | ND | ND |
| Azerbaijan | Exact | Exact | ND |
| Belarus | ND | ND | ND |
| Bosnia & Herzegovina | ND | ND | ND |
| Bulgaria | Exact | Exact | ND |
| Cyprus | ND | Exact | Exact |
| Czech Republic | Exact | Exact | Exact |
| Denmark | ND | Exact | Exact |
| Finland | ND | ND | Exact |
| France | ND | ND | ND |
| Germany | Exact | Exact | Exact |
| Greece | Est. | Est. | Est. |
| Hungary | Est | Est. | Exact |
| Ireland | Exact | Exact | Exact |
| Italy | ND | ND | ND |
| Latvia | ND | ND | ND |
| Lithuania | Est. | Est. | ND |
| Macedonia | ND | Exact | ND |
| Montenegro | Exact | Exact | ND |
| The Netherlands | Est. | ND | ND |
| Poland | ND | ND | ND |
| Portugal | ND | Exact | ND |
| Romania | ND | ND | ND |
| Slovakia | Exact | Exact | ND |
| Slovenia | Exact | Exact | ND |
| Sweden | Exact | Exact | ND |
| Switzerland | ND | ND | ND |
| Ukraine | ND | ND | ND |
| United Kingdom | Est. | ND | ND |
List of countries that provided or did not provide data
| COUNTRIES THAT PROVIDED DATA | COUNTRIES THAT DID NOT PROVIDE DATA |
|---|---|
| Albania | Armenia |
| Austria | Belgium |
| Azerbaijan | Croatia |
| Belarus | Estonia Estonia and Russia responded, but were not able to provide any data |
| Bosnia & Herzegovina | Georgia |
| Bulgaria | Iceland |
| Cyprus | Israel |
| Czech Republic | Kyrgyzstan |
| Denmark | Luxembourg |
| Finland | Moldova |
| France | Norway |
| Germany | Russia Estonia and Russia responded, but were not able to provide any data |
| Greece | Serbia |
| Hungary | Spain |
| Ireland | Turkey |
| Italy | |
| Latvia | |
| Lithuania | |
| Macedonia | |
| Montenegro | |
| Poland | |
| Portugal | |
| Romania | |
| Slovakia | |
| Slovenia | |
| Sweden | |
| Switzerland | |
| The Netherlands | |
| UK | |
| Ukraine |
Countries providing exact figures, estimates or no data on total population infected with HCV (question 4) and infection status (question 5)
| COUNTRY | TOTAL INFECTED WITH HCV | INFECTED WITH HCV & STILL ALIVE | CO-INFECTED WITH HIV |
|---|---|---|---|
| Albania | Est. | ND* | Exact |
| Austria | Exact | ND* | Exact |
| Azerbaijan | Est. | ND* | ND |
| Belarus | Est. | ND* | ND |
| Bosnia & Herzegovina | Est. | ND* | ND |
| Bulgaria | Est. | ND* | ND |
| Cyprus | Est. | Exact | Exact |
| Czech Republic | Est. | Exact | Exact |
| Denmark | Exact | ND* | Exact |
| Finland | Est | ND* | Exact |
| France | Exact | ND* | Exact |
| Germany | Est. | Exact | Exact |
| Greece | Est. | Exact | Exact |
| Hungary | Exact | ND* | Exact |
| Ireland | Exact | Exact | Exact |
| Italy | Est. | Exact | Exact |
| Latvia | ND | ND* | ND |
| Lithuania | Est. | ND* | Exact |
| Macedonia | Est. | ND* | Exact |
| Montenegro | Exact | ND* | Exact |
| The Netherlands | Exact | ND* | ND |
| Poland | ND | ND* | ND |
| Portugal | Est. | ND* | Exact |
| Romania | Est. | ND* | ND |
| Slovakia | Exact | Exact | Exact |
| Slovenia | Exact | Exact | Exact |
| Sweden | Exact | Exact | Exact |
| Switzerland | Est. | ND* | ND |
| Ukraine | Est. | ND* | Exact |
| United Kingdom | Est. | ND* | Exact |
Percentage of PWBD with HCV achieving SVR with second-generation DAAs
| COUNTRY | PWBD ACHIEVING SVR WITH SECOND-GENERATION DAAS (%) |
|---|---|
| Germany | 40 |
| Ireland | 24 |
| Cyprus | 11 |
| Denmark | 8 |
| Czech Rep. | 5 |
| Hungary | 4 |
| Greece | 3 |
| Finland | 3 |
Countries where PWBD infected with HCV have been compensated
| ALL PWBD | SOME PWBD | NEVER COMPENSATED |
|---|---|---|
| Cyprus | Albania | Austria |
| France | Germany | Czech Republic |
| Hungary | UK | Denmark |
| Ireland | Italy | Greece |
| Sweden | Macedonia | |
| Montenegro | ||
| The Netherlands | ||
| Portugal | ||
| Slovakia | ||
| Slovenia |