[1. Lane S. Haemorrhagic diathesis: successful transfusion of blood. Lancet 1940; 41(i): 185-188.10.1016/S0140-6736(00)40031-0]Search in Google Scholar
[2. Kurachi K, Davie EW. Isolation and characterization of a cDNA coding for human factor IX. Proc Natl Acad Sci USA 1982; 79(21): 6461-4.10.1073/pnas.79.21.6461]Search in Google Scholar
[3. Gitschier J, Wood WI, Goralka TM, et al. Characterization of the human factor VIII gene. Nature 1984; 312(5992): 326-30.10.1038/312326a0]Search in Google Scholar
[4. Wood WI, Capon DJ, Simonsen CC, et al. Expression of active human factor VIII from recombinant DNA clones. Nature 1984; 312(5992): 330-7.10.1038/312330a0]Search in Google Scholar
[5. Vehar GA, Keyt B, Eaton D, et al. Structure of human factor VIII. Nature 1984; 312(5992): 337-42.10.1038/312337a0]Search in Google Scholar
[6. Toole JJ, Knopf JL, Wozney JM, et al. Molecular cloning of a cDNA encoding human antihaemophilic factor. Nature 1984; 312(5992): 342-7.10.1038/312342a0]Search in Google Scholar
[7. Powell JS, Pasi KJ, Ragni MV, et al. Phase 3 study of recombinant factor IX Fc fusion protein in hemophilia B. N Engl J Med 2013; 369(24): 2313-23. doi: 10.1056/NEJMoa1305074.]Search in Google Scholar
[8. Mahlangu J, Powell JS, Ragni MV, et al. Phase 3 study of recombinant factor VIII Fc fusion protein in severe hemophilia A. Blood 2014; 123(3): 317-25. doi: 10.1182/blood-2013-10-529974.]Search in Google Scholar
[9. Collins PW, Fischer K, Morfini M, et al. Implications of coagulation factor VIII and IX pharmacokinetics in the prophylactic treatment of haemophilia. Haemophilia 2011; 17: 2-10.10.1111/j.1365-2516.2010.02370.x]Search in Google Scholar
[10. Chowdary P, Lethagen S, Friedrich U, et al. Safety and pharmacokinetics of anti-TFPI antibody (concizumab) in healthy volunteers and patients with hemophilia: a randomized first human dose trial. J Thromb Haemost 2015; 13(5): 743-54. doi: 10.1111/jth.12864.]Search in Google Scholar
[11. Sehgal A, Barros S, Ivanciu L, et al. An RNAi therapeutic targeting antithrombin to rebalance the coagulation system and promote hemostasis in hemophilia. Nat Med 2015; 21(5): 492-7. doi: 10.1038/nm.3847.]Search in Google Scholar
[12. Müller J, Isermann B, Dücker C, et al. An exosite-specific ssDNA aptamer inhibits the anticoagulant functions of activated protein C and enhances inhibition by protein C inhibitor. Chem Biol 2009; 16(4): 442-51. doi: 10.1016/j.chembiol.2009.03.007.]Search in Google Scholar
[13. Muto A, Yoshihashi K, Takeda M, et al. Anti-factor IXa/X bispecific antibody ACE910 prevents joint bleeds in a long-term primate model of acquired hemophilia A. Blood 2014; 124(20): 3165-71. doi: 10.1182/blood-2014-07-585737.]Search in Google Scholar