<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Cytokines are small pleiotropic polypeptids secreted dominantly by the cells of the immune system. These polypeptids are main mediators of innate and acquired immunity, responsible for clonal expansion and differentiation of immune cells, initiation of immune response and enhancing of effector functions of leukocytes. Cytokine-related effects are most studied in the fields of inflammation, immunology, and cancer biology. In this review we discuss one of the most intriguing, recently discovered proinflammatory cytokine, interleukin 32.</p></abstract>

Cytokines are small pleiotropic polypeptids secreted dominantly by the cells of the immune system. These polypeptids are main mediators of innate and acquired immunity, responsible for clonal expansion and differentiation of immune cells, initiation of immune response and enhancing of effector functions of leukocytes. Cytokine-related effects are most studied in the fields of inflammation, immunology, and cancer biology. In this review we discuss one of the most intriguing, recently discovered proinflammatory cytokine, interleukin 32.

Interleukin-32 in Infection, Inflammation and Cancer Biology

Department of Surgery, Faculty of Medical Sciences

Experimental and Applied Biomedical Research (EABR)

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"Interleukin-32 in Infection, Inflammation and Cancer Biology"}

Cytokines are small pleiotropic polypeptids secreted dominantly by the cells of the immune system. These polypeptids are main mediators of innate and acquired...

Interleukin-32 in Infection, Inflammation and Cancer Biology

Published Online: Jun 05, 2020

Page range: 75 - 82

Received: Sep 20, 2016

Accepted: Oct 26, 2016

DOI: https://doi.org/10.1515/sjecr-2016-0085

Keywords
Interleukin 32, infection, inflammation, tumor

© 2020 Mladen Pavlovic et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Interleukin-32 in Infection, Inflammation and Cancer Biology

Published Online: Jun 05, 2020

Page range: 75 - 82

Received: Sep 20, 2016

Accepted: Oct 26, 2016

DOI: https://doi.org/10.1515/sjecr-2016-0085

KeywordsInterleukin 32, infection, inflammation, tumor

© 2020 Mladen Pavlovic et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
Interleukin 32, infection, inflammation, tumor