[1. Hanahan D, Weinberg RA. (2000). The hallmarks of cancer. Cell. 100; 57-70.10.1016/S0092-8674(00)81683-9]Search in Google Scholar
[2. Sotiriou C, Pusztai L. (2009). Gene-expression signatures in breast cancer. N Engl J Med. 360; 790-800.10.1056/NEJMra0801289]Search in Google Scholar
[3. Acharya A, Das I, Chandhok D, Saha T. (2010). Redox regulation in cancer: A double-edged sword with therapeutic potential. Oxid Med Cell Longev. 3; 23-34.10.4161/oxim.3.1.10095]Search in Google Scholar
[4. Milner JA. (2004). Molecular targets for bioactive food components. J Nutr. 134; 2492S-2498S.]Search in Google Scholar
[5. Fenech M, Ferguson LR. (2001). Vitamins/minerals and genomic stability in humans. Mut Res. 475; 1-6.10.1016/S0027-5107(01)00069-0]Search in Google Scholar
[6. Ivetic M, Velicki R, Popovic M, Cemerlic-Adjic N, Babovic SS, Velicki L. (2010). Dietary influence on breast cancer. Journal of BUON. 15(3); 455-461.]Search in Google Scholar
[7. Siewit CL, Gengler B, Vegas E, Puckett R, Louie MC. (2010). Cadmium promotes breast cancer cell proliferation by potentiating the interaction between Er_ and c-Jun. Molecular Mol Endocrinol. 24(5); 981-992.10.1210/me.2009-0410]Search in Google Scholar
[8. Gallagher CM, Chen JJ, Kovach JS. (2010). Enviromental cadmium and breast cancer risk. Aging. 2(11); 804-814.10.18632/aging.100226]Search in Google Scholar
[9. McElroy JA, Shafer MM, Trentham-Dietz A, Hampton JM, Newcomb PA. (2006). Cadmium exposure and breast cancer risk. J Natl Cancer Inst. 98(12); 896-873.10.1093/jnci/djj233]Search in Google Scholar
[10. Sandstead HH. (1994). Understanding zinc: recent observations and interpretations. J Lab Clin Med. 124(3); 322-327.]Search in Google Scholar
[11. Heyneman CA. (1996). Zinc deficiency and taste disorders. Ann Pharmacother. 30(2); 186-187.]Search in Google Scholar
[12. HoE, Ames BN. (2002). Low intracellular zinc induces oxidative DNA damage, disrupts p53, NFkappa B, and AP1 DNA binding, and affects DNA repair in a rat glioma cell line. Proc Natl Acad Sci U S A. 99(26); 16770-1675.10.1073/pnas.222679399]Search in Google Scholar
[13. Fuwa K, Wacker WE, Druyan R, Bartholomay AF, Vallee BL. (1960). Nucleic Acids and Metals II: Transition Metals as Determinants of the Conformation of Ribonucleic Acids. Proc Natl Acad Sci USA. 46; 1298-1307.10.1073/pnas.46.10.1298]Search in Google Scholar
[14. Paski SC, Xu Z. (2001). Labile intracellular zinc is associated with 3T3 cell growth. J Nutr Biochem. 12; 655-661.10.1016/S0955-2863(01)00188-7]Search in Google Scholar
[15. Andreini C, Banci L, Bertini I, Rosato A. (2006). Counting the zinc-proteins encoded in the human genome. J Proteome Res. 5; 196-201.10.1021/pr050361j]Search in Google Scholar
[16. Sekler I, Sensi SL, Hershfinkel M, Silverman WF. (2007). Mechanism and regulation of cellular zinc transport. Mol Med. 13; 337-343.10.2119/2007-00037.Sekler]Search in Google Scholar
[17. Gaither LA, Eide DJ. (2001). Eukaryotic zinc transporters and their regulation. Biometals. 14; 251-270.]Search in Google Scholar
[18. McClelland RA, Manning DL, Gee JM, Wishler P, Robertson JF, Ellis IO, Blamey RW, Nicholson RI. (1998). Oestrogen-regulated gene sin breast cancer: Association of pLIV1 with response to endocrine therapy. Br _ Cancer. 77; 1653-1656.10.1038/bjc.1998.271]Search in Google Scholar
[19. Vašák M, Hasler DW. (2000). Metallothioneins: new functional and structural insights. Curr Opin Chem Biol. 4(2); 177-183.]Search in Google Scholar
[20. Andreini C, Banci L, Bertini I, Rosato A. (2006). Counting the zinc-proteins encoded in the human genome. J Proteome Res. 5(1); 196-201.10.1021/pr050361j]Search in Google Scholar
[21. Liuzzi JP, Cousins RJ. (2004). Mammalian zinc transporters. Annu Rev Nutr. 24; 151-172.]Search in Google Scholar
[22. DeWys W, Pories W. (1972). Inhibition of spectrum of animal tumors by dietary zinc deficiency. J Natl Cancer Inst. 48(2); 375-381.]Search in Google Scholar
[23. McQuitty JT Jr, DeWys WD, Monaco L, Strain WH, Rob CG, Apgar J, Pories WJ. (1970). Inhibition of tumor growth by dietary zinc deficiency. Cancer Res. 30(5); 1387-1390.]Search in Google Scholar
[24. Chakravarty PK, GhoshA, Chowdhury JR. (1976). Zinc in human malignances. Neoplasma. 33(1); 85-90.]Search in Google Scholar
[25. Mulay IL, Roy R, Knox BE, Suhr NH, Delaney WE. (1971). Trace-metal analysis of cancerous and non cancerous human tissues. J Natl Cancer Inst. 47(1); 1-13.]Search in Google Scholar
[26. Chasapis CT, Luotsidou AC, Spiliopoulou, Stefanidou ME. (2013). Zinc and human health: an update. Arch Toxicol. 86(4); 521-534.]Search in Google Scholar
[27. Margalioth EJ, Schenker JG, Chevion M. 1983. Cooper and zinc levels in normal and malignant tissues. Cancer. 52(5); 866-872.10.1002/1097-0142(19830901)52:5<868::AID-CNCR2820520521>3.0.CO;2-K]Search in Google Scholar
[28. Alam S, Kelleher SL. (2012). Cellular mechanisms of zinc dysregulation: _ perspective on zinc homeostasis as an etiological factor in the development and progression of breast cancer. Nutritiens. 4(8); 875-903. 10.3390/nu4080875]Search in Google Scholar
[29. El-Tanani MK, Green CD. (1995). Oestrogen-induced genes, pLIV-1 and pS2, respond divergently to other steroid hormones in MCF-7 cells. Mol Cell Endocrinol. 111(1); 75-81.10.1016/0303-7207(95)03550-Q]Search in Google Scholar
[30. Taylor KM, Morgan HE, Johnson A, Hadley LJ, Nicholson RI. (2003); Structure-function analysis of LIV-1, the breast cancer-associated protein that belongs to a new subfamily of zinc transporters. Biochem J. 375(Pt1); 51-59.10.1042/bj20030478]Search in Google Scholar
[31. Kagara N, Tanaka N, Noguchi S, Hirano T. (2007). Zinc and its transporter ZIP10 are involved in invasive behavior of breast cancer cells. Cancer Sci. 98(5); 692-697.10.1111/j.1349-7006.2007.00446.x]Search in Google Scholar
[32. Zhao L, Chen W, _aylor KM, Cai B, Li X. (2007). LIV-1 suppression inhibits HeLa cell invasion by targeting ERK/2-Snail/Slug pathway. Biochem Biophys Res Commun. 363(1); 82-88.10.1016/j.bbrc.2007.08.127]Search in Google Scholar
[33. Kelleher SL, Seo YA, Lopez V. (2009). Mammary gland zinc metabolism: regulation and dysregulation. Genes Nutr. 4(2); 83-94.10.1007/s12263-009-0119-4]Search in Google Scholar
[34. Lichten LA, Cousins RJ. (2009). Mammalian zinc transporters: nutritional and physiologic regulation. Annu rev nutr. 29; 153-176.]Search in Google Scholar
[35. McClelland RA, Manning DL, Gee JM, Willsher P, Robertson JF, Ellis IO, Blamey RW, Nicholson RI. (1998). Oestrogen-regulated genes in breast cancer: _ssociation of pLIV1 with response to endocrine therapy. Br J Cancer. 77(10); 1653-1656.10.1038/bjc.1998.271]Search in Google Scholar
[36. Manning DL, McClelland RA, Gee JM, Chan Cm, Green CD, Blamey RW, Nicholson RI. (1993). The role of four oestrogen-responsive genes, pLIV1, pS2, pSYD3 and pSYD8, in predicting responsiveness to endocrine therapy in primary breast cancer. Eur J Cancer. 29A(10); 1462-1468.10.1016/0959-8049(93)90021-7]Search in Google Scholar
[37. Taylor KM, Nicholson RI. (2003). The LZT proteins; the LIV-1 subfamily of zinc transporters. Biochim Biophysic Acta. 1611(1-2); 16-30.]Search in Google Scholar
[38. Egeblad M, Werb Z. (2002). New functions for the matrix metalloproteinases in cancer progression. Nat Rev Cancer. 2(3); 161-174.10.1038/nrc745]Search in Google Scholar
[39. Lopez V, Foolad F, Kelleher SL. (2011). ZnT2-overexpression represses the cytotoxic effects of zinc hyperaccumulation in malignant metallothionein-null T47D breast tumor cells. Cancer Lett. 304(1); 41-51.10.1016/j.canlet.2011.01.027]Search in Google Scholar
[40. Truong-Tran AQ, Ho LH, Chai F, Zalewski PD. (2000). Cellular zinc fluxes and the regulation of apoptosis/genedirected cell death. J Nutr. 130(5S Suppl); 1459-1466.10.1093/jn/130.5.1459S]Search in Google Scholar
[41. Seo YA, Lopez V, Kelleher SL. (2011). A histidine-rich motif mediates mitochondrial localization of ZnT2 to modulate mitochondrial function. Am J Physiol Cell Physiol. 300(6); 1479-1489.10.1152/ajpcell.00420.2010]Search in Google Scholar
[42. Prasad AS, Beck FW, Endre L, Handschu W, Kukuruga M, Kumar G. (1996). Zinc deficiency affects cell cycle and deoxythymidine kinase gene expression in HUT-78 cells. J Lab Clin Med. 128(1); 51-60.10.1016/S0022-2143(96)90113-4]Search in Google Scholar
[43. Paski SC, Xu Z. (2002). Growth factor stimulated cell proliferation is accompanied by an elevated labile intracellular pool of zinc in 3T3 cells. Can J Physiol Pharmacol. 80(8); 790-795.10.1139/y02-101]Search in Google Scholar
[44. Franklin RB, Costello LC. (2009). The important role of the apoptotic effects of zinc in the development of cancers. J Cell Biochem. 106(5); 750-757.]Search in Google Scholar
[45. Provinciali M, Di Stefano G, Fabris N. (1995). Dosedependent opposite effect of zinc on apoptosis in mouse thymocytes. Int J Immunopharmacol. 17(9); 735-744.10.1016/0192-0561(95)00063-8]Search in Google Scholar
[46. Djekovic A, Petrovic B, Bugarcic ZD, Puchta R, van Eldik R. (2012). Kinetics and mechanism of the reactions of Au(III) complexes with some biologically relevant molecules. Dalton Trans. 41(13); 3633-3641.10.1039/c2dt11843b22318647]Search in Google Scholar
[47. Wang Y, He QY, Sun RW, Che CM, Chiu JF. (2005). GoldIII porphyrin 1a induced apoptosis by mitochondrial death pathways related to reactive oxygen species. Cancer Res. 65(24); 11553-11564.10.1158/0008-5472.CAN-05-286716357165]Search in Google Scholar
[48. Lum CT, Liu X, Sun RW, Li XP, Peng Y, He ML, Kung HF, Che CM, Lin MC. (2010). Gold(III) porphyrin 1a inhibited nasopharyngeal carcinoma metastasis in vivo and inhibited cell migration and invasion in vitro. Cancer Lett. 294(2); 159-166.10.1016/j.canlet.2010.01.03320163914]Search in Google Scholar
[49. Jacques A, Lebrun C, Casini A, Kieffer I, Proux O, Latour JM, Sénèque O. (2015). Reactivity of Cys4 zinc finger domains with gold(III) complexes: insights into the formation of „gold fingers“. Inorg Chem. 54(8); 4104-4113.10.1021/acs.inorgchem.5b0036025839236]Search in Google Scholar
[50. Arsenijevic N. (2012). Biological Effects of Gold(III) Complexes Tested in Vitro and in Vivo. In: Kretsinger RH, Uversky VN & Permiyakov EA. Encyclopedia of Metalloproteins ( pp. 933-935). New York, Heidelberg, Dordrecht, London:Springer.]Search in Google Scholar
[51. Jain S, Coulter JA, Hounsell AR, Butterworth KT, Mc- Mahon SJ, Hyland WB, Muir MF, Dickson GR, Prise KM, Currell FJ, O’Sullivan JM, Hirst DG. (2011). Cell- Specific radiosensitization by gold nanoparticles at megavoltage radiation energies. Int J Radial Oncol Biol Phys. 79(2); 531-539.10.1016/j.ijrobp.2010.08.044301517221095075]Search in Google Scholar
[52. Paciotti GF, Myer L, Weinreich D, Goia D, Pavel N, McLaughlin RE, Tamarkin L. (2004). Colloidal gold: a novel nanoparticle vector for tumor directed drug delivery. Drug Deliv. 11(3); 169-183.10.1080/1071754049043389515204636]Search in Google Scholar
[53. Huschka R, Zuloaga J, Knight MW, Brown LV, Nordlander P, Halas NJ. (2011). Light-induced release of DNA from gold nanoparticles: nanoshells and nanorods. J Am Chem. Soc. 133(31); 12247-12255.10.1021/ja204578e410830221736347]Search in Google Scholar
[54. Gibson JD, Khanal BP, Zubarev ER. (2007). Paclitaxelfunctionalized gold nanoparticles. J Am Chem Soc. 129(37); 11653-11661.10.1021/ja075181k17718495]Search in Google Scholar
[55. Liu H, Chen D, Li L, Liu T, Tan L, Wu X, Tang F. (2011). Multifunctional gold nanoshells on silica nanorattles: a platform for the combination of photothermal therapy and chemotherapy with low systemic toxicity. Angew Chem Int Ed Engl. 50(4); 891-895.]Search in Google Scholar
[56. You J, Zhang R, Zhang G, Zhong M, Liu Y, Van Pelt CS, Liang D, Wei W, Sood AK, Li C. (2012). Photothermalchemotherapy with doxorubicin-loaded hollow gold nanospheres: _ platform for near-infrared light-trigged drug release. J Control Release. 158(2); 319-328. 10.1016/j.jconrel.2011.10.028346323922063003]Search in Google Scholar
[57. Lee J, Chatterjee DK, Lee MH, Krishnan S. (2014). Gold nanoparticles in breast cancer treatment: promise and potential pitfalls. Cancer Lett. 347(1); 46-53.10.1016/j.canlet.2014.02.006414206224556077]Search in Google Scholar
[58. Stuchinskaya T, Moreno M, Cook MJ, Edwards DR, Russell DA. (2011). Targeted photodynamic therapy of breast cancer cells using antibody-phthalocyaninegold nanoparticle conjugates. Photochem Photobiol Sci. 10(5); 822-831.10.1039/c1pp05014a21455532]Search in Google Scholar
[59. Xu C, Wang B, Sun S. (2009). Dumbbell-like Au-Fe3O4 nanoparticles for target-specific platin delivery. J Am Chem Soc. 131(12); 4216-4217.10.1021/ja900790v267139719275156]Search in Google Scholar
[60. Joshi P, Chakraborti S, Ramirez-Vick JE, Ansari ZA, Shanker V, Chakrabarti P, Singh SP. (2012). The anticancer activity of chloroquine-gold nanoparticles against MCF-7 breast cancer cells. Colloid Surf B Biointerfaces. 95; 195-200. 10.1016/j.colsurfb.2012.02.03922445746]Search in Google Scholar