<abstract xmlns="http://www.w3.org/1999/xhtml"><p>The present paper is a literature review of the recent years dealing with the most important separation techniques of fatty acids in biological samples. Our aim was to make a synthesis of the analytical methods used, to note the most used ones, but also to mention other methods that are less utilized, which can have important advantages (such as less time consuming, greener reagents, etc.). Gas-chromatographic separation methods were described and compared to liquid chromatographic separations of fatty acids in different types of biological samples. In the same time, the importance of determining fatty acids profiles in biological samples was revealed, pointing out the possible implications in diagnostics of different types of disorders or remarking different profiles compared to healthy states.</p></abstract>

The present paper is a literature review of the recent years dealing with the most important separation techniques of fatty acids in biological samples. Our aim was to make a synthesis of the analytical methods used, to note the most used ones, but also to mention other methods that are less utilized, which can have important advantages (such as less time consuming, greener reagents, etc.). Gas-chromatographic separation methods were described and compared to liquid chromatographic separations of fatty acids in different types of biological samples. In the same time, the importance of determining fatty acids profiles in biological samples was revealed, pointing out the possible implications in diagnostics of different types of disorders or remarking different profiles compared to healthy states.

Recent developments in fatty acids profile determination in biological samples - a review

University of Medicine and Pharmacy “I. Hatieganu”, Cluj-Napoca, Romania

Revista Romana de Medicina de Laborator

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Progrese recente în determinarea acizilor graşi din probe biologice - un review

The present paper is a literature review of the recent years dealing with the most important separation techniques of fatty acids in biological samples. Our...

Recent developments in fatty acids profile determination in biological samples - a review

Published Online: Dec 30, 2015

Page range: 371 - 384

Received: Jun 23, 2015

Accepted: Sep 13, 2015

DOI: https://doi.org/10.1515/rrlm-2015-0035

Keywords
fatty acids, gas-chromatography, liquid-chromatography, biological samples

© 2015 Ioana Tiuca et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Recent developments in fatty acids profile determination in biological samples - a review

Published Online: Dec 30, 2015

Page range: 371 - 384

Received: Jun 23, 2015

Accepted: Sep 13, 2015

DOI: https://doi.org/10.1515/rrlm-2015-0035

Keywordsfatty acids, gas-chromatography, liquid-chromatography, biological samples

© 2015 Ioana Tiuca et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
fatty acids, gas-chromatography, liquid-chromatography, biological samples