[1. CIOFFI M, ROSA AD, SERAO R, et al. Laboratory markers in ulcerative colitis: Current insights and future advances. World J Gastrointest Pathophysiol. 2015; 6(1):13-22.10.4291/wjgp.v6.i1.13]Search in Google Scholar
[2. MENDOZA JL, ABREU MT. Biological markers in inflammatory bowel disease: practical consideration for clinicians.Gastroenterol Clin Biol. 2009; 33 Suppl 3:S158.10.1016/S0399-8320(09)73151-3]Search in Google Scholar
[3. HENRIKSEN M, JAHNSEN J, LYGREN I, et al. C-reactive protein a predictive factor and marker of inflammation in inflammatory bowel disease. Results from a prospective population-based study. Gut. 2008; 57(11):1518-23.10.1136/gut.2007.14635718566104]Search in Google Scholar
[4. VAN RHEENEN PF, VAN DE VIJVER E, FIDLER V. Faecal calprotectin for screening of patients with suspected inflammatory bowel disease: diagnostic meta-analysis. BMJ 2010; 341:c3369.10.1136/bmj.c3369290487920634346]Search in Google Scholar
[5. VON ROON AC, KARAMOUNTZOS L, PURKAYASTHA S, et al. Diagnostic precision of fecal calprotectin for inflammatory bowel disease and colorectal malignancy. Am J Gastroenterol 2007; 102: 803-813.10.1111/j.1572-0241.2007.01126.x17324124]Search in Google Scholar
[6. TRAVIS SP, FARRANT JM, RICKETTS C, et al. Predicting outcome in severe ulcerative colitis. Gut 1996; 38:905–910.10.1136/gut.38.6.90513832008984031]Search in Google Scholar
[7. BOSCHETTI G, GARNERO P, MOUSSATA D, et al. Accuracies of Serum and Fecal S100 Proteins (Calprotectin and Calgranulin C) to Predict the Response to TNF Antagonists in Patients with Crohn's Disease. Inflamm Bowel Dis. 2015; 21(2):331-6.10.1097/MIB.000000000000027325625487]Search in Google Scholar
[8. KISS LS, SZAMOSI T, MOLNAR T, et al. Early clinical remission and normalisation of CRP are the strongest predictors of efficacy, mucosal healing and dose escalation during the first year of adalimumab therapy in Crohn's disease. Aliment Pharmacol Ther. 2011; 34(8):911-22.10.1111/j.1365-2036.2011.04827.x21883326]Search in Google Scholar
[9. MOOIWEER E, SEVERS M, SCHIPPER ME, et al. Low fecal calprotectin predicts sustained clinical remission in inflammatory bowel disease patients: a plea for deep remission. J Crohns Colitis. 2015; 9(1):50-5.10.1093/ecco-jcc/jju00325518048]Search in Google Scholar
[10. D'HAENS G, FERRANTE M, VERMEIRE S, et al. Fecal calprotectin is a surrogate marker for endoscopic lesions in inflammatory bowel disease. Inflamm Bowel Dis. 2012; 18(12):2218-24.10.1002/ibd.2291722344983]Search in Google Scholar
[11. SCHOEPFER AM, BEGLINGER C, STRAUMANN A, et al. Ulcerative colitis: correlation of the Rachmilewitz endoscopic activity index with fecal calprotectin, clinical activity, C-reactive protein, and blood leukocytes. Inflamm Bowel Dis 2009; 15: 1851-1858.10.1002/ibd.2098619462421]Search in Google Scholar
[12. SIPPONEN T, KÄRKKÄINEN P, SAVILAHTI E, et al. Correlation of faecal calprotectin and lactoferrin with an endoscopic score for Crohn's disease and histological findings. Aliment Pharmacol Ther 2008; 28: 1221-1229.10.1111/j.1365-2036.2008.03835.x18752630]Search in Google Scholar
[13. FROSLIE KF, JAHNSEN J, MOUM BA, et al. Mucosal healing in inflammatory bowel disease: results from a Norwegian population-based cohort. Gastroenterology 2007; 133:412-22.10.1053/j.gastro.2007.05.05117681162]Search in Google Scholar
[14. COSTA F, MUMOLO MG, CECCARELLI L, et al. Calprotectin is a stronger predictive marker of relapse in ulcerative colitis than in Crohn’s disease. Gut. 2005; 54(3):364-8.10.1136/gut.2004.043406177440115710984]Search in Google Scholar
[15. NAISMITH GD, SMITH LA, BARRY SJ, et al. A prospective evaluation of the predictive value of faecal calprotectin in quiescent Crohn’s disease. J Crohns Colitis. 2014; 8(9):1022-9.10.1016/j.crohns.2014.01.02924566170]Search in Google Scholar
[16. CESARO A, ANCERIZ N, PLANTE A, et al. An inflammation loop orchestrated by S100A9 and calprotectin is critical for the development of arthritis. PLoS One. 2012; 7(9): e45478.10.1371/journal.pone.0045478344552723029038]Search in Google Scholar
[17. FEGHALI CA, WRIGHT TM. Cytokines in acute and chronic inflammation. Front Biosci. 1997 1; (2):d12-26.10.2741/A1719159205]Search in Google Scholar
[18. VERMEIRE S, VAN ASSCHE G, RUTGEERTS P.C-reactive protein as a marker for inflammatory bowel disease. Inflamm Bowel Dis. 2004; 10(5):661-5.10.1097/00054725-200409000-0002615472532]Search in Google Scholar
[19. VATAY A, BENE L, KOVÁCS A, et al. Relationship between the tumor necrosis factor alpha polymorphism and the serum C-reactive protein levels in inflammatory bowel disease. Immunogenetics. 2003; 55(4):247-52.10.1007/s00251-003-0575-812811429]Search in Google Scholar
[20. COLOMBEL JF, RUTGEERTS P, REINISCH W, et al. Early mucosal healing with infliximab is associated with improved longterm clinical outcomes in ulcerative colitis. Gastroenterology 2011; 141:1194-201.10.1053/j.gastro.2011.06.05421723220]Search in Google Scholar
[21. FENG JS, YANG Z, ZHU YZ, et al. Serum IL-17 and IL-6 increased accompany with TGF-β and IL-13 respectively in ulcerative colitis patients. Int J Clin Exp Med. 2014; 7(12):5498-504.]Search in Google Scholar
[22. OWCZAREK D, CIBOR D, GŁOWACKI MK, et al. TNF-α and soluble forms of TNF receptors 1 and 2 in the serum of patients with Crohn's disease and ulcerative colitis. Pol Arch Med Wewn. 2012; 122(12):616-23.10.20452/pamw.153723160117]Search in Google Scholar
[23. SCHROEDER KW, TREMAINE WJ, ILSTRUP DM. Coated oral 5-aminosalicylic acid therapy for mildly to moderately active ulcerative colitis. A randomized study. N Engl J Med 1987; 317: 1625–9.10.1056/NEJM1987122431726033317057]Search in Google Scholar
[24. VAN ASSCHE G, DIGNASS A, PANES J, et al. European Crohn's and Colitis Organisation (ECCO). The second European evidence-based Consensus on the diagnosis and management of Crohn's disease: Definitions and diagnosis. J Crohns Colitis. 2010; 4(1):7-2710.1016/j.crohns.2009.12.00321122488]Search in Google Scholar
[25. DIGNASS A, ELIAKIM R, MAGRO F, et al. Second European evidence-based consensus on the diagnosis and management of ulcerative colitis part 1: definitions and diagnosis. J Crohns Colitis. 2012; 6(10):965-90.10.1016/j.crohns.2012.09.00323040452]Search in Google Scholar
[26. SCHOEPFER AM, VAVRICKA S, ZAHND-STRAUMANN N, et al. Monitoring infammatory bowel disease activity: clinical activity is judged to be more relevant than endoscopic severity or biomarkers. J Crohns Colitis 2012; 6:412-418.10.1016/j.crohns.2011.09.00822398068]Search in Google Scholar
[27. RODA G, CAPONI A, BENEVENTO M, et al. New proteomic approaches for biomarker discovery in inflammatory bowel disease. Inflamm Bowel Dis. 2010; 16(7):1239-46.10.1002/ibd.2121220127998]Search in Google Scholar
[28. FAUBION WA JR1, FLETCHER JG, O'BYRNE S, et al. EMerging BiomARKers in Inflammatory Bowel Disease (EMBARK) study identifies fecal calprotectin, serumMMP9, and serum IL-22 as a novel combination of biomarkers for Crohn's disease activity: role of cross-sectional imaging. Am J Gastroenterol. 2013; 108(12):1891-900.10.1038/ajg.2013.35424126633]Search in Google Scholar
[29. DE VOS M, LOUIS EJ, JAHNSEN J, et al. Consecutive fecal calprotectin measurements to predict relapse in patients with ulcerative colitis receiving infliximab maintenance therapy. Inflamm Bowel Dis. 2013; 19(10):2111.10.1097/MIB.0b013e31829b2a3723883959]Search in Google Scholar
[30. SCHMIDT C, GIESE T, HERMANN E, et al. Predictive value of mucosal TNF-alpha transcripts in steroid-refractory Crohn's disease patients receiving intensive immunosuppressive therapy. Inflamm Bowel Dis. 2007;13(1):65-70.10.1002/ibd.2001217206641]Search in Google Scholar
[31. DIONNE S, HISCOTT J, D'AGATA I et al. Quantitative PCR analysis of TNF-alpha and IL-1 beta mRNA levels in pediatric IBD mucosal biopsies. Dig Dis Sci. 1997; 42(7):1557-66.10.1023/A:1018895500721]Search in Google Scholar
[32. MARTÍNEZ-BORRA J, LÓPEZ-LARREA C, GONZÁLEZ S, et al. High serum tumor necrosis factor-alpha levels are associated with lack of response to infliximab in fistulizing Crohn's disease. Am J Gastroenterol. 2002; 97(9):2350-6.10.1111/j.1572-0241.2002.05990.x12358255]Search in Google Scholar
[33. SYDORA MJ, SYDORA BC, FEDORAK RN. Validation of a point-of-care desk top device to quantitate fecal calprotectin and distinguish inflammatory bowel disease from irritable bowel syndrome. J Crohns Colitis. 2012; 6(2):207-1410.1016/j.crohns.2011.08.00822325175]Search in Google Scholar
[34. VOIOSU T, BENGUŞ A, DINU R, et al. Rapid fecal calprotectin level assessment and the SIBDQ score can accurately detect active mucosal inflammation in IBD patients in clinical remission: a prospective study. J Gastrointestin Liver Dis. 2014; 23(3):273-8.10.15403/jgld.2014.1121.233.thv25267955]Search in Google Scholar
[35. SCHOEPFER AM, BEGLINGER C, STRAUMANN A, et al. Fecal calprotectin correlates more closely with the Simple Endoscopic Score for Crohn's disease (SES-CD) than CRP, blood leukocytes, and the CDAI. Am J Gastroenterol 2010; 105: 162-169.10.1038/ajg.2009.54519755969]Search in Google Scholar
[36. YOON JY, PARK SJ, HONG SP et al. Correlations of C-reactive protein levels and erythrocyte sedimentation rates with endoscopic activity indices in patients with ulcerative colitis. Dig Dis Sci. 2014; 59(4):829-37.10.1007/s10620-013-2907-324352705]Search in Google Scholar
[37. SCHOEPFER AM, BEGLINGER C, STRAUMANN A, et al. Fecal calprotectin more accurately reflects endoscopic activity of ulcerative colitis than the Lichtiger Index, C-reactive protein, platelets, hemoglobin, and blood leukocytes. Inflamm Bowel Dis. 2013; 19(2):332-41.10.1097/MIB.0b013e318281006623328771]Search in Google Scholar
[38. LEWIS JD. The utility of biomarkers in the diagnosis and therapy of inflammatory bowel disease. Gastroenterology. 2011; 140(6):1817-1826.10.1053/j.gastro.2010.11.058374929821530748]Search in Google Scholar
[39. MARTÍNEZ-BORRA J, LÓPEZ-LARREA C, GONZÁLEZ S, et al. High serum tumor necrosis factorα are associated with lack of response to infliximab in fistulizing Crohn’s disease. Am J Gastroenterol 2002; 97(9):2350-6.]Search in Google Scholar
[40. OLSEN T, GOLL R, CUI G et al. Tissue levels of tumor necrosis factor-alpha correlates with grade of inflammation in untreated ulcerative colitis. Scand J Gastroenterol. 2007; 42(11):1312-20.10.1080/0036552070140903517852866]Search in Google Scholar
[41. KOMATSU M, KOBAYASHI D, SAITO K. Tumor necrosis factor-alpha in serum of patients with inflammatory bowel disease as measured by a highly sensitive immuno-PCR. Clin Chem. 2001; 47(7):1297-301.10.1093/clinchem/47.7.1297]Search in Google Scholar
[42. RODRÍGUEZ-PERÁLVAREZ ML, GARCÍA-SÁNCHEZ V, VILLAR-PASTOR CM, et al. Role of serum cytokine profile in ulcerative colitis assessment. Inflamm Bowel Dis. 2012; 18(10):1864-71.10.1002/ibd.2286522238172]Search in Google Scholar
[43. DE VOS M, LOUIS EJ, JAHNSEN J, et al. Consecutive fecal calprotectin measurements to predict relapse in patients with ulcerative colitis receiving infliximab maintenance therapy. Inflamm Bowel Dis. 2013; 19(10):2111-7.10.1097/MIB.0b013e31829b2a3723883959]Search in Google Scholar
[44. GARCÍA-SÁNCHEZ V, IGLESIAS-FLORES E, GONZÁLEZ R, et al. Does fecal calprotectin predict relapse in patients with Crohn's disease and ulcerative colitis? J Crohns Colitis. 2010; 4(2):144-52.10.1016/j.crohns.2009.09.00821122498]Search in Google Scholar