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The impact of outpatient clinical care on the survival and hospitalisation rate in patients with alcoholic liver cirrhosis

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| Dec 07, 2017

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Radiology and Oncology

Volume 52 (2018): Issue 1 (March 2018)

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Article Category: Research Article

Published Online: Dec 07, 2017

Page range: 75 - 82

Received: Sep 11, 2017

Accepted: Oct 15, 2017

DOI: https://doi.org/10.1515/raon-2017-0056

© 2018 Dejan Majc, Bojan Tepes

This article is distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Five-year survival of patients according to the Child-Pugh classification

CHILD	Group	All	Number of deaths	Survivors		p value

				Number	Percent
A	Study	32	13	19	59.4%	0.035
	Control	51	29	22	43.1%
	Both	83	42	41	49.4%
B	Study	21	11	10	47.6%	0.083
	Control	23	14	9	39.1%
	Both	44	25	19	43.2%
C	Study	43	25	18	41.9%	0.006
	Control	27	22	5	18.5%
	Both	70	47	23	32.9%

	Total	197	114	83	42.1%

The number of hospitalizations and outpatient examinations in study and control groups over 5 years

	Study group	Control group	p value
Total number of outpatient examinations over 5 years	543	229	0.00
Average number of outpatient examinations in 5 years (per patient)	5.54	2.27	0.00
Total number of hospitalizations over 5 years	184	209	0.612
Average number of hospitalizations in 5 years (per patient)	1.88	2.07	0.612

Demographic characteristics of patients with liver cirrhosis in the study group and the control group

		Study group		Control group		Both groups

		Number	%	Number	%	Number	%
	Male	79	80.6%	80	79.2%	159	79.9%
Gender	Female	19	19.4%	21	20.8%	40	20.1%
	Total	98		101		199
Age (mean)		58.2		59.1		58.6
Standard deviation		10.8		11.3		11.1

Child-Pugh stage and complications of liver cirrhosis in both groups

		Study group		Control group		Both groups

		Number	%	Number	%	Number	%
Child-Pugh classification	A	33	33.7%	51	50.5%	84	42.2%
	B	21	21.4%	23	22.8%	44	22.1%
	C	44	44.9%	27	26.7%	71	35.7%
	Total	98		101		199
Varices	Without	21	21.4%	18	17.8%	39	19.6%
	I. Grade	27	27.6%	14	13.9%	41	20.6%
	II. Grade	20	20.4%	17	16.8%	37	18.6%
	III. Grade	25	25.5%	22	21.8%	47	23.6%
	IV. Grade	2	2.0%	3	3.0%	5	2.5%
	Unknown	3	3.1%	27	26.7%	30	15.1%
	Total	98		101		199
Portal gastropathy	Yes	63	64.3%	39	38.6%	102	51.3%
	No	32	32.7%	23	22.8%	55	27.6%
	Unknown	3	3.1%	39	38.6%	42	21.1%
	Total	98		101		199
Ascites	Yes	37	37.8%	46	46.0%	83	41.9%
	No	61	62.2%	54	54.0%	115	58.1%
	Total	98		100		198
Peripheral oedema	No	45	46.4%	67	66.3%	112	56.6%
	Yes	52	53.6%	34	33.7%	86	43.4%
	Total	97		101		198

Concomitant diseases in both groups

		Study group		Control group		Total
								p
		Nb.	%	Nb.	%	Nb.	%
Stroke	Yes	96	98.0%	99	98.0%	195	98.0%
	No	2	2.0%	2	2.0%	4	2.0%	0.84
	Total	98		101		199
Atrial fibrillation	No	86	87.8%	90	89.1%	176	88.4%
	Yes	12	12.2%	11	10.9%	23	11.6%	0.78
	Total	98		101		199
Arterial hypertension	No	70	71.4%	86	85.1%	156	78.4%
	Yes	28	28.6%	15	14.9%	43	21.6%	0.21
	Total	98		101		199
Heart failure	No	87	88.8%	88	87.1%	175	87.9%
	Yes	11	11.2%	13	12.9%	24	12.1%	0.17
	Total	98		101		199
Diabetes	No	77	78.6%	78	77.2%	155	77.9%
	Yes	21	21.4%	23	22.8%	44	22.1%	0.77
	Total	98		101		199
Renal failure	No	74	75.5%	73	72.3%	147	73.9%
	Yes	24	24.5%	28	27.7%	52	26.1%	0.34
	Total	98		101		199

Comparison of all patients who died in the hospital because of a complication or multiple complications of liver cirrhosis (one patient may have more than one complication)

	Study group (n)	Control group (n)	p
Hepatic encephalopathy	12	13	0.320
Spontaneous bacterial peritonitis	5	5
Hepatorenal syndrome	12	14	0.158
Bleeding	4	4
Infections	14	13	0.320
Heart failure	3	8	0.025
Alcoholic hepatitis	4	6	0.158
Total number of patient deaths	39	49

Alcohol consumption and treatment in the Ormož Psychiatric Hospital for both groups

	Study group %	Control group %	p value
No alcohol consumption	56.12	35.64	0.000
Alcohol consumption	43.88	64.36	0.018
Ormož Psychiatry	14.85	15.30	0.158

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