<abstract xmlns="http://www.w3.org/1999/xhtml"><sec id="j_raon-2016-0005_s_001_w2aab3b8b7b1b7b1aab1c16b1Aa"><h3>Background</h3><p>Slovenia has a high burden of head and neck cancer. Patients are mostly treated with surgery followed by radiation therapy. Advanced surgical and prosthodontic techniques have expanded the rehabilitation options. The aim of the study was to review the outcome of implant-prosthetic treatment after radiation therapy.</p></sec><sec id="j_raon-2016-0005_s_002_w2aab3b8b7b1b7b1aab1c16b2Aa"><h3>Patients and methods</h3><p>Twenty irradiated head and neck cancer patients who received a removable implant-supported denture at the University Medical Centre Ljubljana were included in the study. Kaplan-Meier survival analysis, Cox proportional hazard models and logistic regression were used to assess the implant survival and success rate.</p></sec><sec id="j_raon-2016-0005_s_003_w2aab3b8b7b1b7b1aab1c16b3Aa"><h3>Results</h3><p>Twenty patients had 100 implants inserted. The estimated implant survival rate was 96% after 1 year and 87% after 5 years. Failures were mostly observed before loading (91.2%). Implants inserted in the transplanted bone were significantly more likely to fail. Out of 89 implants supporting the dentures, 79 implants (88.7%) were successful, meaning that they were functionally loaded and exhibited no pain, radiolucency or progressive bone loss. Prosthetic treatment was significantly less successful in older patients. The attachment system and the number of implants did not have a statistically significant influence on the success rate.</p></sec><sec id="j_raon-2016-0005_s_004_w2aab3b8b7b1b7b1aab1c16b4Aa"><h3>Conclusions</h3><p>Implant-supported dentures have been shown to be a reliable treatment modality after head and neck cancer surgery and radiation therapy. Possible early failures should be communicated with the patients.</p></sec></abstract>

BackgroundSlovenia has a high burden of head and neck cancer. Patients are mostly treated with surgery followed by radiation therapy. Advanced surgical and prosthodontic techniques have expanded the rehabilitation options. The aim of the study was to review the outcome of implant-prosthetic treatment after radiation therapy.Patients and methodsTwenty irradiated head and neck cancer patients who received a removable implant-supported denture at the University Medical Centre Ljubljana were included in the study. Kaplan-Meier survival analysis, Cox proportional hazard models and logistic regression were used to assess the implant survival and success rate.ResultsTwenty patients had 100 implants inserted. The estimated implant survival rate was 96% after 1 year and 87% after 5 years. Failures were mostly observed before loading (91.2%). Implants inserted in the transplanted bone were significantly more likely to fail. Out of 89 implants supporting the dentures, 79 implants (88.7%) were successful, meaning that they were functionally loaded and exhibited no pain, radiolucency or progressive bone loss. Prosthetic treatment was significantly less successful in older patients. The attachment system and the number of implants did not have a statistically significant influence on the success rate.ConclusionsImplant-supported dentures have been shown to be a reliable treatment modality after head and neck cancer surgery and radiation therapy. Possible early failures should be communicated with the patients.

Implant-prosthetic rehabilitation after radiation treatment in head and neck cancer patients: a case-series report of outcome

Department of Prosthodontics, Faculty of Medicine

Department of Maxillofacial and Oral Surgery, Faculty of Medicine

Department of Maxillofacial and Oral Surgery

Radiology and Oncology

This article is distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

BackgroundSlovenia has a high burden of head and neck cancer. Patients are mostly treated with surgery followed by radiation therapy. Advanced surgical and...

Implant-prosthetic rehabilitation after radiation treatment in head and neck cancer patients: a case-series report of outcome

Article Category: Research Article

Published Online: Feb 07, 2016

Page range: 94 - 100

Received: Nov 27, 2015

Accepted: Jan 06, 2016

DOI: https://doi.org/10.1515/raon-2016-0005

Keywords
head and neck cancer, radiation therapy, dental implants, implant-supported dentures

© 2017 Jasna Cotic, Jure Jamsek, Milan Kuhar, Natasa Ihan Hren, Andrej Kansky, Mutlu Özcan, Peter Jevnikar

This article is distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Implant-prosthetic rehabilitation after radiation treatment in head and neck cancer patients: a case-series report of outcome

Article Category: Research Article

Published Online: Feb 07, 2016

Page range: 94 - 100

Received: Nov 27, 2015

Accepted: Jan 06, 2016

DOI: https://doi.org/10.1515/raon-2016-0005

Keywordshead and neck cancer, radiation therapy, dental implants, implant-supported dentures

© 2017 Jasna Cotic, Jure Jamsek, Milan Kuhar, Natasa Ihan Hren, Andrej Kansky, Mutlu Özcan, Peter Jevnikar

This article is distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Keywords
head and neck cancer, radiation therapy, dental implants, implant-supported dentures