Influence of Metabolic Cage on Wistar Rat Physiological State

1. Gordon, C.J., Fogelson, L. (1994). Metabolic and thermoregulatory responses of the rat maintained in acrylic or wire-screen cages: implications for pharmacological studies. Physiology & Behavior 56(1): 73–79. http://dx.doi.org/10.1016/0031-9384(94)90263-110.1016/0031-9384(94)90263-1Search in Google Scholar

2. Kurien, B.T., Everds, N.E., Scofield, R.H. (2004). Experimental animal urine collection: a review Laboratory Animals Ltd. Laboratory Animals 38, 333–361. http://dx.doi.org/10.1258/0023677041958945 PMid:1547954910.1258/0023677041958945Search in Google Scholar

3. EU (2010) Directive 2010/63 EU of the European Parliament and of the Council of 22 September 2010 on the protection of animals used for scientific purposes. Official Journal of the European Communities L276, pp. 33–79.Search in Google Scholar

4. Eriksson, E., Royo, F.K, Lyberg Carlsson, H-E., Hau, J. (2004). Effect of metabolic cage housing on immunoglobulin A and corticosterone excretion in faeces and urine of young male rats. Experimental Physiology 89(4): 427–433. http://dx.doi.org/10.1113/expphysiol.2004.027656 PMid:1513107510.1113/expphysiol.2004.027656Search in Google Scholar

5. Heidbreder, C.A., Weiss, I.C., Domeney, A.M., Pryce, C., Homberg, J., Hedou, G., Feldon, J. Moran, M.C., Nelson, P. (2000). Behavioral, neurochemical and endocrinological characterization of the early social isolation syndrome. Neuroscience 100(4): 749–768. http://dx.doi.org/10.1016/S0306-4522(00)00336-510.1016/S0306-4522(00)00336-5Search in Google Scholar

6. Krohn, T.C., Hansen, A.K., Dragsted, N. (2003). Telemetry as a method for measuring the impact of housing conditions on rat’s welfare. Animal Welfare 12(1): 53–62.Search in Google Scholar

7. Manser, C.E. Morris, T.H., Broom, D.M. (1995). An investigation into the effects of solid or grid cage flooring on the welfare of laboratory rats. Laboratory Animals 29(4): 353–363. http://dx.doi.org/10.1258/002367795780740023 PMid:855881610.1258/002367795780740023Search in Google Scholar

8. Cvek-Hopkins K. (2007). Effect of metabolic cage housing on rodent welfare. SLU Uppsala, 7–9.Search in Google Scholar

9. Yamada, K., Ohki-Hamazaki, H., Wada, K. (2000). Differential effects of social isolation upon body weight, food consumption, and responsiveness to novel and social environment in bombesin receptor subtype-3 (BRS-3) deficient mice. Physiology & Behavior 68, 555–561. http://dx.doi.org/10.1016/S0031-9384(99)00214-010.1016/S0031-9384(99)00214-0Search in Google Scholar

10. Balcombe, J.P., Barnard, N.D, Sandusky, C. (2004). Laboratory routines cause animal stress. Contemp Top Lab Anim Sci. 43, 42–51. PMid:15669134Search in Google Scholar

11. Sjaastad, Ø.V., Hove, K., Sand, O. (2003). Physiology of Domestic Animals (pp. 141, 224, 226–227, 241). First edition. Oslo: Scandinavian Veterinary Press.Search in Google Scholar

12. Qiang, D., Salva, A., Sottas, C.M., Niu, E., Holmes, M., Hardy, M.P. (2004). Rapid glucocorticoid mediation of suppressed testosterone biosynthesis in male mice subjected to immobilization stress. Journal of Andrology 25(6): 973–981.Search in Google Scholar

13. Hunt, C., Hambly, C. (2006). Faecal corticosterone concentrations indicate that separately housed male mice are not more stressed than group housed males. Physiology & Behavior 87, 519–526. http://dx.doi.org/10.1016/j.physbeh.2005.11.013 PMid:1644213510.1016/j.physbeh.2005.11.01316442135Search in Google Scholar

14. Nagy, T.R., Krzywanski, D., Li, J., Meleth, S., Desmond, R. (2002). Effect of group vs. single housing on phenotypic variance in C57BL/6J mice. Obesity Research 10, 412–415. http://dx.doi.org/10.1038/oby.2002.57 PMid:1200664210.1038/oby.2002.5712006642Search in Google Scholar

15. Spangenberg, E.M.F., Augustsson, H., Dahlborn, K., Essén-Gustavsson, B., Cvek, K. (2005). Housing related activity in rats: effects on body weight, urinary corticosterone levels, muscle properties and performance. Laboratory Animals 39, 45–57. http://dx.doi.org/10.1258/0023677052886457 PMid:1570312410.1258/002367705288645715703124Search in Google Scholar

16. D’Arbe, M., Einstein, R., Lavidis, N.A. (2002). Stressful animal housing conditions and their potential effect on sympathetic neurotransmission in mice. The American Journal of Physiology. Regulatory, Intergrative and Comparative Physiology 282, 1422–1428. http://dx.doi.org/10.1152/ajpregu.00805.2000 PMid:1195968510.1152/ajpregu.00805.200011959685Search in Google Scholar

17. Gil, M.C., Aguirre, J.A., Lemoine, A.P., Segura, E.T., Barontini, M.I. (1999). Influence of age on stress responses to metabolic cage housing in rats. Cellular and Molecular Neurobiologi 19(5): 625–633. http://dx.doi.org/10.1023/A:1006984402291 PMid:1038426010.1023/A:1006984402291Search in Google Scholar

18. Ollson, I.A.S., Westlund, K. (2007). The effect of social factors on behavior and welfare of laboratory rodents and non-human primates. Appl. Anim. Behav. Sci. 103, 229–254. http://dx.doi.org/10.1016/j.applanim.2006.05.02210.1016/j.applanim.2006.05.022Search in Google Scholar

19. Freymann J., Tsai, P.P., Stelzer, H., Hackbarth, H. (2015). The amount of cage bedding preferred by female BALB/c and C57BL/6 mice. Lab animal Europe 15 (2): 13–19.Search in Google Scholar

20. Hirsjärvi, P., Väliaho, T. (1995). Gentled and nonhandled Wistar rats in a mildly novel open-field situation. Scandinavian Journal of Laboratory Animal Science 22 (3): 265–269.Search in Google Scholar

21. Van Loo, P.L.P., Kruitwagen, C.L.J.J., Van Zutphen, L.F.M., Koolhaas, J.M., Baumans, V. (2000). Modulation of aggression in male mice: influence of cage cleaning regime and scent marks. Anim Welf. 9, 281–295.10.1017/S0962728600022752Search in Google Scholar

22. Armario, A., Montero, J.L., Balasch, J. (1986). Sensitivity of corticosterone and some metabolic variables to graded levels of low intensity stresses in adult male rats. Physiol Behav. 37, 559–561. http://dx.doi.org/10.1016/0031-9384(86)90285-410.1016/0031-9384(86)90285-4Search in Google Scholar

23. Castelhano-Carlos, M.J., Baumans, V. (2009). The impact of light, noise, cage cleaning and in-house transport on welfare and stress of laboratory rats. Laboratory Animals 43, 311–327. http://dx.doi.org/10.1258/la.2009.0080098 PMid:1950593710.1258/la.2009.0080098Search in Google Scholar

24. De Boer, S.F., Koopmans, S.J., Slangen, J.L., Van der Gugten, J. (1990). Plasma catecholamine, corticosterone and glucose responses to repeated stress in rats. Effect of interstressor interval length. Physiol Behav 47, 1117–1124. http://dx.doi.org/10.1016/0031-9384(90)90361-710.1016/0031-9384(90)90361-7Search in Google Scholar