<abstract xmlns="http://www.w3.org/1999/xhtml"><bold>Introduction:</bold> The purpose of this study was to investigate the therapeutic effect of hydrogen on the therapy of onion poisoned dogs.<bold>Material and Methods:</bold> A total of 16 adult beagle dogs were divided into two groups (control and hydrogen) and all were fed dehydrated onion powder at the dose of 10 g/kg for three days. The dogs of the experimental group were given subcutaneous injection of 0.2 mL/kg of hydrogen for 12 days after making the poisoned model successful. Blood samples were collected before feeding onions, one day before injecting hydrogen, and 2 h after the injection of hydrogen on days 1, 3, 5, 7, 9, and 12. Control dogs were not treated with hydrogen.<bold>Results:</bold> The levels of leukocyte production, anaemia, red blood cell degeneration which was reflected by the values of Heinz body count, haemolytic ratio, and oxidative products in hydrogen treated group were lower than in control dogs on some days. The capacity of medullary haematopoiesis that was based on reticulocyte counts, and the antioxidation in hydrogen group were higher compared with control group. However, the differences in renal function were not obvious in both groups.<bold>Conclusion:</bold> Accordingly, it was concluded that subcutaneous injection of hydrogen could alleviate the symptoms in onion poisoned dogs.</abstract>

Introduction: The purpose of this study was to investigate the therapeutic effect of hydrogen on the therapy of onion poisoned dogs.Material and Methods: A total of 16 adult beagle dogs were divided into two groups (control and hydrogen) and all were fed dehydrated onion powder at the dose of 10 g/kg for three days. The dogs of the experimental group were given subcutaneous injection of 0.2 mL/kg of hydrogen for 12 days after making the poisoned model successful. Blood samples were collected before feeding onions, one day before injecting hydrogen, and 2 h after the injection of hydrogen on days 1, 3, 5, 7, 9, and 12. Control dogs were not treated with hydrogen.Results: The levels of leukocyte production, anaemia, red blood cell degeneration which was reflected by the values of Heinz body count, haemolytic ratio, and oxidative products in hydrogen treated group were lower than in control dogs on some days. The capacity of medullary haematopoiesis that was based on reticulocyte counts, and the antioxidation in hydrogen group were higher compared with control group. However, the differences in renal function were not obvious in both groups.Conclusion: Accordingly, it was concluded that subcutaneous injection of hydrogen could alleviate the symptoms in onion poisoned dogs.

Therapeutic effect of hydrogen injected subcutaneously on onion poisoned dogs

Heilongjiang Key Laboratory for Laboratory Animals and Comparative Medicine

Journal of Veterinary Research

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"Therapeutic effect of hydrogen injected subcutaneously on onion poisoned dogs"}

Introduction: The purpose of this study was to investigate the therapeutic effect of hydrogen on the therapy of onion poisoned dogs.Material and Methods: A...

Therapeutic effect of hydrogen injected subcutaneously on onion poisoned dogs

Published Online: Dec 27, 2017

Page range: 527 - 533

Received: Jul 11, 2017

Accepted: Dec 06, 2017

DOI: https://doi.org/10.1515/jvetres-2017-0068

Keywords
dogs, onion poisoning, hydrogen, therapy

© 2017 Jinghua Zhao et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Therapeutic effect of hydrogen injected subcutaneously on onion poisoned dogs

Published Online: Dec 27, 2017

Page range: 527 - 533

Received: Jul 11, 2017

Accepted: Dec 06, 2017

DOI: https://doi.org/10.1515/jvetres-2017-0068

Keywordsdogs, onion poisoning, hydrogen, therapy

© 2017 Jinghua Zhao et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
dogs, onion poisoning, hydrogen, therapy