<abstract xmlns="http://www.w3.org/1999/xhtml"><p>There are numerous biomarkers of central and peripheral nervous system damage described in human and veterinary medicine. Many of these are already used as tools in the diagnosis of human neurological disorders, and many are investigated in regard to their use in small and large animal veterinary medicine. The following review presents the current knowledge about the application of cell-type (glial fibrillary acidic protein, neurofilament subunit NF-H, myelin basic protein) and central nervous system specific proteins (S100B, neuron specific enolase, tau protein, alpha II spectrin, ubiquitin carboxy-terminal hydrolase L1, creatine kinase BB) present in the cerebrospinal fluid and/or serum of animals in the diagnosis of central or peripheral nervous system damage in veterinary medicine.</p></abstract>

There are numerous biomarkers of central and peripheral nervous system damage described in human and veterinary medicine. Many of these are already used as tools in the diagnosis of human neurological disorders, and many are investigated in regard to their use in small and large animal veterinary medicine. The following review presents the current knowledge about the application of cell-type (glial fibrillary acidic protein, neurofilament subunit NF-H, myelin basic protein) and central nervous system specific proteins (S100B, neuron specific enolase, tau protein, alpha II spectrin, ubiquitin carboxy-terminal hydrolase L1, creatine kinase BB) present in the cerebrospinal fluid and/or serum of animals in the diagnosis of central or peripheral nervous system damage in veterinary medicine.

Biomarkers of injury to neural tissue in veterinary medicine

Department of Internal Diseases with Clinic for Diseases of Horses, Dogs and Cats, Wroclaw University of Environmental and Life Sciences, 50-375 Wroclaw

Centre for Experimental Diagnostics and Biomedical Innovations, Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Sciences, 50-375 Wroclaw

Journal of Veterinary Research

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"Biomarkers of injury to neural tissue in veterinary medicine"}

There are numerous biomarkers of central and peripheral nervous system damage described in human and veterinary medicine. Many of these are already used as...

Biomarkers of injury to neural tissue in veterinary medicine

Published Online: Sep 23, 2016

Page range: 365 - 371

Received: Feb 07, 2016

Accepted: Jul 21, 2016

DOI: https://doi.org/10.1515/jvetres-2016-0053

Keywords
animals, central nervous system damage, biomarkers, review

© 2016 Marta Płonek et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Biomarkers of injury to neural tissue in veterinary medicine

Published Online: Sep 23, 2016

Page range: 365 - 371

Received: Feb 07, 2016

Accepted: Jul 21, 2016

DOI: https://doi.org/10.1515/jvetres-2016-0053

Keywordsanimals, central nervous system damage, biomarkers, review

© 2016 Marta Płonek et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
animals, central nervous system damage, biomarkers, review