<abstract xmlns="http://www.w3.org/1999/xhtml"><bold>Introduction:</bold> The aim of this study was to investigate fluorescein use in the diagnosis of bladder ruptures in rabbits as an experimental model.<bold>Material and Methods:</bold> The study was conducted on male New Zealand rabbits divided into a retrograde fluorescein group (n = 8) and an intravenous (IV) fluorescein group (n = 8). Following general anaesthesia, 10 mL of 10% fluorescein dye (sodium fluoresceine powder) was administered <italic>via</italic> ureterorenoscope to the bladder of the first group, and 0.5 mL of 10% fluorescein was administered intravenously to the second group. Then, the bladder was viewed through the cystoscope by urethral aspect. After experimental bladder perforation, groups were comparatively evaluated by paracentesis and laparotomy.<bold>Results:</bold> Following IV injection of fluorescein dye, the bladder veins were stained green within 10 s and then fluorescein mixed with urine flowed into bladder lumen. The green fluid flow was observed in the abdominal cavity after the perforation of the bladder in both groups.<bold>Conclusion:</bold> Fluorescein can be used as a marker in diagnosis of bladder ruptures. If there is no bleeding or intestinal content in the abdominal cavity, although a smoky yellow-green image is observed, bladder rupture can be suspected.</abstract>

Introduction: The aim of this study was to investigate fluorescein use in the diagnosis of bladder ruptures in rabbits as an experimental model.Material and Methods: The study was conducted on male New Zealand rabbits divided into a retrograde fluorescein group (n = 8) and an intravenous (IV) fluorescein group (n = 8). Following general anaesthesia, 10 mL of 10% fluorescein dye (sodium fluoresceine powder) was administered via ureterorenoscope to the bladder of the first group, and 0.5 mL of 10% fluorescein was administered intravenously to the second group. Then, the bladder was viewed through the cystoscope by urethral aspect. After experimental bladder perforation, groups were comparatively evaluated by paracentesis and laparotomy.Results: Following IV injection of fluorescein dye, the bladder veins were stained green within 10 s and then fluorescein mixed with urine flowed into bladder lumen. The green fluid flow was observed in the abdominal cavity after the perforation of the bladder in both groups.Conclusion: Fluorescein can be used as a marker in diagnosis of bladder ruptures. If there is no bleeding or intestinal content in the abdominal cavity, although a smoky yellow-green image is observed, bladder rupture can be suspected.

Fluorescein as a diagnostic marker of bladder ruptures: an experimental study on rabbit model

Faculty of Veterinary Medicine Department of Surgery, Kafkas University, TR-36300, Kars, Turkey

Faculty of Medicine Department of Urology, Kafkas University, TR-36300, Kars, Turkey

Faculty of Medicine Department of Ophtalmology, Kafkas University, TR-36300, Kars, Turkey

Journal of Veterinary Research

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Introduction: The aim of this study was to investigate fluorescein use in the diagnosis of bladder ruptures in rabbits as an experimental model.Material and...

Fluorescein as a diagnostic marker of bladder ruptures: an experimental study on rabbit model

Published Online: May 28, 2016

Page range: 213 - 217

Received: Apr 13, 2015

Accepted: May 10, 2016

DOI: https://doi.org/10.1515/jvetres-2016-0031

Keywords
rabbit, bladder rupture, fluorescein, cystoscopy, catheterisation

© 2016 Özgür Aksoy et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Fluorescein as a diagnostic marker of bladder ruptures: an experimental study on rabbit model

Published Online: May 28, 2016

Page range: 213 - 217

Received: Apr 13, 2015

Accepted: May 10, 2016

DOI: https://doi.org/10.1515/jvetres-2016-0031

Keywordsrabbit, bladder rupture, fluorescein, cystoscopy, catheterisation

© 2016 Özgür Aksoy et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
rabbit, bladder rupture, fluorescein, cystoscopy, catheterisation