<abstract xmlns="http://www.w3.org/1999/xhtml"><p>The current practice in the field of forensic medicine imposes the use of modern investigation techniques. The complexity of laboratory investigation methods needed for a final result of the investigation in forensic medicine needed new biomarkers of higher specificity and selectivity. Such biomarkers are the microRNAs (miRNAs), short, non-coding RNAs composed of 19–24 nucleotides. Their characteristics, such as high stability, selectivity, and specificity for biological fluids, differ from tissue to tissue and for certain pathologies, turning them into the ideal candidate for laboratory techniques used in forensic medicine. In this paper, we wish to highlight the biochemical properties and the usefulness of miRNAs in forensic medicine.</p></abstract>

The current practice in the field of forensic medicine imposes the use of modern investigation techniques. The complexity of laboratory investigation methods needed for a final result of the investigation in forensic medicine needed new biomarkers of higher specificity and selectivity. Such biomarkers are the microRNAs (miRNAs), short, non-coding RNAs composed of 19–24 nucleotides. Their characteristics, such as high stability, selectivity, and specificity for biological fluids, differ from tissue to tissue and for certain pathologies, turning them into the ideal candidate for laboratory techniques used in forensic medicine. In this paper, we wish to highlight the biochemical properties and the usefulness of miRNAs in forensic medicine.

Use of Circulating and Cellular miRNAs Expression in Forensic Sciences

“Victor Babeș” University of Medicine and Pharmacy

Journal of Interdisciplinary Medicine

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"Use of Circulating and Cellular miRNAs Expression in Forensic Sciences"}

The current practice in the field of forensic medicine imposes the use of modern investigation techniques. The complexity of laboratory investigation methods...

Use of Circulating and Cellular miRNAs Expression in Forensic Sciences

Published Online: Nov 08, 2017

Page range: 235 - 241

Received: Jul 27, 2017

Accepted: Aug 17, 2017

DOI: https://doi.org/10.1515/jim-2017-0074

Keywords
miRNA expression, forensic biomarkers, noninvasive detection

© 2017 Raluca Dumache et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Use of Circulating and Cellular miRNAs Expression in Forensic Sciences

Published Online: Nov 08, 2017

Page range: 235 - 241

Received: Jul 27, 2017

Accepted: Aug 17, 2017

DOI: https://doi.org/10.1515/jim-2017-0074

KeywordsmiRNA expression, forensic biomarkers, noninvasive detection

© 2017 Raluca Dumache et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
miRNA expression, forensic biomarkers, noninvasive detection