<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Complex hemodynamic, neurohormonal and biochemical changes occur in heart failure and chronic kidney disease, and hyperglycemia/diabetes further accentuate the multifactorial pathogenetic mechanisms. The acknowledgement of concomitant heart and kidney dysfunction in patients with type 2 diabetes has major clinical implications with regards to prognosis, as they significantly increase the risk of mortality, and to therapeutical strategy of both conditions, as well as of hyperglycemia. A comprehensive interdisciplinary approach is needed in these cases in order to improve the outcomes.</p></abstract>

Complex hemodynamic, neurohormonal and biochemical changes occur in heart failure and chronic kidney disease, and hyperglycemia/diabetes further accentuate the multifactorial pathogenetic mechanisms. The acknowledgement of concomitant heart and kidney dysfunction in patients with type 2 diabetes has major clinical implications with regards to prognosis, as they significantly increase the risk of mortality, and to therapeutical strategy of both conditions, as well as of hyperglycemia. A comprehensive interdisciplinary approach is needed in these cases in order to improve the outcomes.

Heart Failure and Chronic Kidney Disease in Type 2 Diabetes

Department M3/Internal Medicine IV, University of Medicine and Pharmacy, Tîrgu Mureş,

Diabetes, Nutrition and Metabolic Diseases Outpatient Unit, County Emergency Clinical Hospital, Tîrgu Mureş,

Journal of Interdisciplinary Medicine

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"Heart Failure and Chronic Kidney Disease in Type 2 Diabetes"}

Complex hemodynamic, neurohormonal and biochemical changes occur in heart failure and chronic kidney disease, and hyperglycemia/diabetes further accentuate the...

Heart Failure and Chronic Kidney Disease in Type 2 Diabetes

Published Online: Dec 29, 2016

Page range: 252 - 258

Received: Dec 08, 2016

Accepted: Dec 21, 2016

DOI: https://doi.org/10.1515/jim-2016-0066

Keywords
type 2 diabetes, heart failure, chronic kidney disease, cardiorenal syndrome

© 2016 Simona Cernea, published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Heart Failure and Chronic Kidney Disease in Type 2 Diabetes

Published Online: Dec 29, 2016

Page range: 252 - 258

Received: Dec 08, 2016

Accepted: Dec 21, 2016

DOI: https://doi.org/10.1515/jim-2016-0066

Keywordstype 2 diabetes, heart failure, chronic kidney disease, cardiorenal syndrome

© 2016 Simona Cernea, published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
type 2 diabetes, heart failure, chronic kidney disease, cardiorenal syndrome