<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Jaundice in sepsis is usually caused by cholestasis, and its onset can precede other manifestations of the infection. Inflammation-induced cholestasis is a common complication in patients with an extrahepatic infection or those with inflammatory processes. We describe the case of a 47 years old female who presented with low back pain and paravertebral muscular contracture. She subsequently developed a cholestatic syndrome with clinical manifestations such as jaundice, followed by fever and sepsis with multiple organ dysfunction. Initially labeled as biliary sepsis, the diagnosis was crucially reoriented as the blood cultures were positive for Streptococcus pyogenes and the magnetic resonance imaging (MRI) findings suggested spondylodiscitis as well as a paravertebral abscess.</p></abstract>

Jaundice in sepsis is usually caused by cholestasis, and its onset can precede other manifestations of the infection. Inflammation-induced cholestasis is a common complication in patients with an extrahepatic infection or those with inflammatory processes. We describe the case of a 47 years old female who presented with low back pain and paravertebral muscular contracture. She subsequently developed a cholestatic syndrome with clinical manifestations such as jaundice, followed by fever and sepsis with multiple organ dysfunction. Initially labeled as biliary sepsis, the diagnosis was crucially reoriented as the blood cultures were positive for Streptococcus pyogenes and the magnetic resonance imaging (MRI) findings suggested spondylodiscitis as well as a paravertebral abscess.

The Pitfalls of Febrile Jaundice. A Case Report

“Sfânta Parascheva” Infectious Diseases Hospital Iași, România

“Grigore T. Popa”University of Medicine and Pharmacy, Iași, România

Department of Medicine, “Sfântul Spiridon” Emergency Clinical Hospital, Iași, România

The Journal of Critical Care Medicine

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"The Pitfalls of Febrile Jaundice. A Case Report"}

Jaundice in sepsis is usually caused by cholestasis, and its onset can precede other manifestations of the infection. Inflammation-induced cholestasis is a...

The Pitfalls of Febrile Jaundice. A Case Report

Published Online: May 09, 2016

Page range: 93 - 95

Received: Feb 02, 2016

Accepted: Apr 03, 2016

DOI: https://doi.org/10.1515/jccm-2016-0013

Keywords
lower back pain, jaundice, fever, blood cultures, sepsis

© 2016 Maria Obreja et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

The Pitfalls of Febrile Jaundice. A Case Report

Published Online: May 09, 2016

Page range: 93 - 95

Received: Feb 02, 2016

Accepted: Apr 03, 2016

DOI: https://doi.org/10.1515/jccm-2016-0013

Keywordslower back pain, jaundice, fever, blood cultures, sepsis

© 2016 Maria Obreja et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
lower back pain, jaundice, fever, blood cultures, sepsis