<abstract xmlns="http://www.w3.org/1999/xhtml"><p> Invasive fungal infections have become a serious problem in the critically ill. One of the main reasons is the development of an immunocompromised condition. The most frequently found pathogens are Candida species. In order to provide adequate treatment, understanding this potentially life-threatening infection is mandatory. The aim of this summary is to view Candida infections from a different perspective and to give an overview on epidemiology, the range of pathophysiology from colonization to the invasive infections, and its impact on mortality. New therapeutic options will also be discussed and how these relate to current guidelines. Finally, the key issue of the choice of antifungal agents will be evaluated.</p></abstract>

Invasive fungal infections have become a serious problem in the critically ill. One of the main reasons is the development of an immunocompromised condition. The most frequently found pathogens are Candida species. In order to provide adequate treatment, understanding this potentially life-threatening infection is mandatory. The aim of this summary is to view Candida infections from a different perspective and to give an overview on epidemiology, the range of pathophysiology from colonization to the invasive infections, and its impact on mortality. New therapeutic options will also be discussed and how these relate to current guidelines. Finally, the key issue of the choice of antifungal agents will be evaluated.

Invasive Candida Infections in the ICU: Diagnosis and Therapy

Department of Anaesthesiology and Intensive Therapy, University of Szeged, Albert Szent-Györgyi Health Center, Szeged, Hungary

Department of Anaesthesiology and Intensive Therapy, University of Szeged, Faculty of Medicine, Department of Anaesthesiology and Intensive Therapy 6. Semmelweis st. 6725 Szeged, Hungary

The Journal of Critical Care Medicine

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

{"article-title":"Invasive Candida Infections in the ICU: Diagnosis and Therapy"}

Invasive fungal infections have become a serious problem in the critically ill. One of the main reasons is the development of an immunocompromised condition....

Invasive Candida Infections in the ICU: Diagnosis and Therapy

Published Online: Nov 10, 2015

Page range: 129 - 139

Received: Jul 02, 2015

Accepted: Sep 15, 2015

DOI: https://doi.org/10.1515/jccm-2015-0025

Keywords
Candida, invasive Candidiasis, diagnostics, therapeutic algorihms

© 2015

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Invasive Candida Infections in the ICU: Diagnosis and Therapy

Published Online: Nov 10, 2015

Page range: 129 - 139

Received: Jul 02, 2015

Accepted: Sep 15, 2015

DOI: https://doi.org/10.1515/jccm-2015-0025

KeywordsCandida, invasive Candidiasis, diagnostics, therapeutic algorihms

© 2015

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Keywords
Candida, invasive Candidiasis, diagnostics, therapeutic algorihms