<abstract xmlns="http://www.w3.org/1999/xhtml"><p>The main objective of this analysis was to define the influence of multivessel disease involvement compared to single vessel disease on mortality rates in STEMI patients. The retrospective study included 549 patients, hospitalized with STEMI in St. Ekaterina University Hospital (age - 62.66±12.56; women - 31.3%) from 01.06.2008 to 30.06.2011. One-vessel disease was found in 232 patients (44%) as compared to two-vessel disease in 165 patients - 31% and multivessel disease in 130 patients - 25%. There was LM stenosis (>30) in 11 patients (2%); ostial lesion in 33 patients (6.3%); presence of Ca in 37 patients (7%). A stent was implanted in 484 patients (91.8%), and GP IIb/IIIa was used in 400 patients (75.9%). There was significant increase in mortality rates in patients with multivessel disease: 15.6% - 46 patients, compared to one-vessel disease - 6.5% (15 patients) (p&lt;=0.01). Both early (30 days) and late mortality (one year) rates were higher in the multivessel group (6.8% vs. 2.6%, p&lt;=0.05 and 10.2% vs. 3.9% (p&lt;=0.0510), respectively. Multivessel disease is associated with higher mortality rates in STEMI patients, which may further alter clinical course and decision making.</p></abstract>

The main objective of this analysis was to define the influence of multivessel disease involvement compared to single vessel disease on mortality rates in STEMI patients. The retrospective study included 549 patients, hospitalized with STEMI in St. Ekaterina University Hospital (age - 62.66±12.56; women - 31.3%) from 01.06.2008 to 30.06.2011. One-vessel disease was found in 232 patients (44%) as compared to two-vessel disease in 165 patients - 31% and multivessel disease in 130 patients - 25%. There was LM stenosis (>30) in 11 patients (2%); ostial lesion in 33 patients (6.3%); presence of Ca in 37 patients (7%). A stent was implanted in 484 patients (91.8%), and GP IIb/IIIa was used in 400 patients (75.9%). There was significant increase in mortality rates in patients with multivessel disease: 15.6% - 46 patients, compared to one-vessel disease - 6.5% (15 patients) (p<=0.01). Both early (30 days) and late mortality (one year) rates were higher in the multivessel group (6.8% vs. 2.6%, p<=0.05 and 10.2% vs. 3.9% (p<=0.0510), respectively. Multivessel disease is associated with higher mortality rates in STEMI patients, which may further alter clinical course and decision making.

Multivessel Disease As A Prognostic Factor For Mortality In STEMI Patients

University Hospital “St. Ekaterina”, Sofia, Bulgaria

Journal of Biomedical and Clinical Research

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"Multivessel Disease As A Prognostic Factor For Mortality In STEMI Patients"}

The main objective of this analysis was to define the influence of multivessel disease involvement compared to single vessel disease on mortality rates in...

Multivessel Disease As A Prognostic Factor For Mortality In STEMI Patients

Published Online: Dec 10, 2015

Page range: 30 - 34

Received: Feb 16, 2015

Accepted: May 18, 2015

DOI: https://doi.org/10.1515/jbcr-2015-0148

Keywords
STEMI, mortality, multi-vessel disease

© 2015 Kiril K. Karamfiloff et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Multivessel Disease As A Prognostic Factor For Mortality In STEMI Patients

Published Online: Dec 10, 2015

Page range: 30 - 34

Received: Feb 16, 2015

Accepted: May 18, 2015

DOI: https://doi.org/10.1515/jbcr-2015-0148

KeywordsSTEMI, mortality, multi-vessel disease

© 2015 Kiril K. Karamfiloff et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
STEMI, mortality, multi-vessel disease