<abstract xmlns="http://www.w3.org/1999/xhtml"><p>This is the first report on the presence and localization of the neurotransmitter serotonin (5-HT) in the nervous system of the nematode <italic>Trichinella pseudospiralis</italic>, the causative agent of trichinellosis. The orientation of the 5-HT-immunoreactive (5-HT-IR) nerve cells in the adult worm is described. In the anterior region of the worm 5-HT-IR occurs in 7 neurons. Longitudinal nerve cords extend posteriorly from the anterior end. They are connected by transverse commissures. The vulval area is intensively supplied with 5-HT-IR nerve cells and fibres forming a plexus. Two rows of small 5HT-IR structures, hypodermal glands, are visible along the whole nematode body. Because of the conserved structural features among nematodes the 5-HT-IR neurons observed are likely to have counterparts in the model worm, <italic>Caenorhabditis elegans</italic>. Some basic differences are evident and demand further study.</p></abstract>

This is the first report on the presence and localization of the neurotransmitter serotonin (5-HT) in the nervous system of the nematode Trichinella pseudospiralis, the causative agent of trichinellosis. The orientation of the 5-HT-immunoreactive (5-HT-IR) nerve cells in the adult worm is described. In the anterior region of the worm 5-HT-IR occurs in 7 neurons. Longitudinal nerve cords extend posteriorly from the anterior end. They are connected by transverse commissures. The vulval area is intensively supplied with 5-HT-IR nerve cells and fibres forming a plexus. Two rows of small 5HT-IR structures, hypodermal glands, are visible along the whole nematode body. Because of the conserved structural features among nematodes the 5-HT-IR neurons observed are likely to have counterparts in the model worm, Caenorhabditis elegans. Some basic differences are evident and demand further study.

Serotonin in <italic>Trichinella pseudospiralis</italic>: An immunocytochemical study

A. N. Severtsov Institute of Ecology and Evolution of Russian Academy of Sciences, Center of Parasitology, 119071 Moscow, Leninsky pr. 33, Russia

All-Russian K. I. Skryabin Scientific Research Institute of Fundamental and Applied Parasitology of Animals and Plants, 117218 Moscow, Bolschaya Cheremushkinskaya 28; Russia

Institute of Cell Biophysics of Russian Academy of Sciences, Moscow Region, Pushchino, Institutskaya 3, Russia

Department of Biosciences, AboAkademi University, 20520 Abo, Finland

Helminthologia

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Serotonin in : An immunocytochemical study

This is the first report on the presence and localization of the neurotransmitter serotonin (5-HT) in the nervous system of the nematode Trichinella...

Serotonin in Trichinella pseudospiralis: An immunocytochemical study

Article Category: Research Article

Published Online: Apr 22, 2016

Page range: 113 - 119

Received: Dec 22, 2015

Accepted: Mar 09, 2016

DOI: https://doi.org/10.1515/helmin-2016-0002

© 2016 Institute of Parasitology, SAS, Košice

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

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