Open Access

Complementary effect of Capparis spinosa L. and silymarin with/without praziquantel on mice experimentally infected with Schistosoma mansoni


Cite

Abdel Aziz, I.Z., El-badry, A., El-Gay, S.H. (2011): In vitro anti-schistosomal activity of Plectranthus tenuiflorus on miracidium, cercaria and schistosomula stages of Schistosoma mansoni. Res. J. Parasitol., 6: 74 – 82. DOI: 10.3923/jp.2011.74.8210.3923/jp.2011.74.82Open DOISearch in Google Scholar

Abdel-Rahman, S.A.M. (2009): Monitoring Th1 and Th2 cytokine patterns after praziquantel and mirazid treatment in experimental mansoniasis. MD. in Parasitology, Egypt, Zagazig: Zagazig UniversitySearch in Google Scholar

Albanis, E., Safadi, R., Friedman, S. (2003): Treatment of hepatic fibrosis: almost there. Curr. Gastroenterol. Rep., 5: 48 – 56. DOI: 10.1007/s11894-003-0009-710.1007/s11894-003-0009-7Open DOISearch in Google Scholar

Ali, S.A. (2011): Natural products as therapeutic agents for schistosomiasis. Res. J. Med. Plant., 5: 1 – 20. DOI: 10.3923/rjmp.2011.1.2010.3923/rjmp.2011.1.20Open DOISearch in Google Scholar

Al-Said, M.S., Abdelsattar, E.A., Khalifa, S.I. El-Feraly, F.S. (1988): Isolation and identification of an anti-inflammatory principle from Capparis spinosa. Pharmazie, 43(9): 640 – 641Search in Google Scholar

Al-Sayed, E., Hamid, H.A., Abu El Einin, H.M. (2014): Molluscicidal and antischistosomal activities of methanol extracts and isolated compounds from Eucalyptus globulus and Melaleuca styphelioides. Pharm. Biol., 52 (6): 698 – 705. DOI: 10.3109/13880209.2013.86524010.3109/13880209.2013.865240Open DOISearch in Google Scholar

Aly, H.F., Mantawy, M.M. (2013): Efficiency of ginger (Zingbar officinale) against Schistosoma mansoni infection during host-parasite association. Parasitol. Int., 62: 380 – 389. DOI:10.1016/j.parint.2013.04.00210.1016/j.parint.2013.04.002Open DOISearch in Google Scholar

Arena, A., Bisignano, G., Pavone, B., Tomaino, A., Bonina, F.P., Saija, A., Cristani, M., D’Arrigo, M. Trombetta, D. (2008): Antiviral and immunomodulatory effect of a lyophilized extract of Capparis spinosa L. buds. Phytother. Res., 22(3): 313 – 317. DOI: 10.1002/ptr.231310.1002/ptr.2313Open DOISearch in Google Scholar

Bataller, R., Brenner, D.A. (2005): Liver fibrosis. J. Clin. Invest., 115: 209 – 218. DOI: 10.1172/JCI20052428210.1172/JCI200524282Open DOISearch in Google Scholar

Batanouny, K. (Ed): (2005). A Guide to Medicinal Plants in North Africa. Malaga Spain, IUCN. 64 pp.Search in Google Scholar

Bigoniya, P., Singh, C.S., Shrivastava, B. (2013): In vivo and in vitro hepatoprotective potential of kaempferol, a flavone glycoside from Capparis spinosa. Int. J. Pharm. Biol. Sci., 3(4): 139 – 152Search in Google Scholar

Bouriche, H., Karnouf, N., Belhadj, H., Dahamna, S., Harzalah, D., Senator, A. (2011): Free Radical, Metal-chelating and Antibacterial Activities of Methonolic Extract of Capparis Spinosa buds. Adv. Enviro. Bio., 5(2): 281 – 287Search in Google Scholar

Burke, M.L., McManus, D.P., Ramm, G.A., Duke, M., Li, Y., Jones, M.K., Gobert, G.N. (2010): Temporal expression of chemokines dictates the hepatic inflammatory infiltrate in a murine model of schistosomiasis. PLOS Negl. Trop. Dis., 4 (2): e598. DOI: 10.1371/journal.pntd.000059810.1371/journal.pntd.0000598Open DOISearch in Google Scholar

Cheever, A.W. (1968): Conditions affecting the accuracy of potassium hydroxide digestion techniques for counting Schistosoma mansoni eggs in tissues. Bull. World Health Organ., 39: 328 – 331Search in Google Scholar

Doenhoff, M.J., Kusel, J.R., Coles, G.C., Cioli. D. (2002): Resistance of Schistosoma mansoni to praziquantel: is there a problem? Trans. R. Soc. Trop. Med. Hyg., 96: 465 – 469. DOI: 10.1016/S0035-9203(02)90405-010.1016/S0035-9203(02)90405-0Open DOISearch in Google Scholar

Duvall, R.H., Dewitt, W.B. (1967): An improved perfusion technique for recovering adult schistosomes from laboratory animals. Am. J. Trop. Med. Hyg., 16(4): 483 – 486. DOI: 10.4269/ajtmh.1967.16.48310.4269/ajtmh.1967.16.4834952149Open DOISearch in Google Scholar

El-Hawary, S., Taha, K., Kirillos, F., Dahab, A., Saleh, N., El-Mahis, A. (2015): Molecular identification, GC/MS and antimicrobial activity of the essential oils and extracts of three Podocarpus species. Int. J. Pharmacog. Phytochem., 30 (2): 1360 – 1369Search in Google Scholar

El-Lakkany, N.M., Hammam, O.A., El-Maadawy, W.H., Badawy, A.A., Ain-Shoka, A.A., Ebeid, F.A. (2012): Anti-inflammatory/anti-fibrotic effects of the hepatoprotective silymarin and the schistosomicide praziquantel against Schistosoma mansoni-induced liver fibrosis. Paras. Vect., 5: 9. DOI: 10.1186/1756-3305-5-910.1186/1756-3305-5-9Open DOISearch in Google Scholar

El-Sisi, A., Awara, W., El-Masry, T., El-Kowrany S., El-Gharbawy R. (2011): Effects and mechanism of action of immunomodulating agents against schistosomiasis-induced hepatic inflammation and fibrosis in mice. Res. Pharm. Biotech., 3: 32 – 45Search in Google Scholar

Fallon, PC., Sturrock, RF., Niang, M. Doenhoff, MJ. (1995): Short report: Diminished susceptibility to praziquantel in a Senegal isolate of Schistosoma mansoni. Am. J. Trop. Med. Hyg., 53: 61 – 62. DOI: 10.4269/ajtmh.1995.53.6110.4269/ajtmh.1995.53.61Open DOISearch in Google Scholar

Farag, M. Mohsen, M., Heinke, R., Wessjohann, L. (2014): Metabolomic fingerprints of 21 date palm fruit varieties from Egypt using UPLC/PDA/ESI-qTOF-MS and GC-MS analyzed by chemometrics. Food Res. Inter., 64: 218 – 226. DOI: 10.1016/j.foodres.2014.06.02110.1016/j.foodres.2014.06.021Open DOISearch in Google Scholar

Feng, X.; Lu, J.; Xin, H.; Zhang, L.; Wang, Y. Tang, K. (2011): Antiarthritic Active fraction of Capparis spinosa L. fruit and its chemical constituents. Yakugaku Zasshi, 131(3): 423 – 42910.1248/yakushi.131.423Search in Google Scholar

Fenwick, A., Savioli, L., Engels, D., Robert Bergquist, N., Todd, M. H. (2003): Drugs for the control of parasitic diseases: current status and development in schistosomiasis. Trends Parasitol., 19: 509 – 515. DOI: 10.1016/j.pt.2003.09.00510.1016/j.pt.2003.09.005Open DOISearch in Google Scholar

Gadgoli, C., Mishra, SH. (1999): Antihepatotoxic activity of p-methoxybenzoic acid from Capparis spinosa. J. Ethnopharmacol., 66: 187 – 190. DOI: 10.1016/S0378-8741(98)00229-310.1016/S0378-8741(98)00229-3Open DOISearch in Google Scholar

Gonnert, R., Andrews, P. (1977): Praziquantel, a new broad-spectrum antischistosomal agent. Z Parasitenkd., 52: 129 – 150. DOI: 10.1007/BF0038989910.1007/BF00389899410178Open DOISearch in Google Scholar

Homeida, M.A., El Tom, I., Nash, T., Bennett, J.L. (1991): Association of the therapeutic activity of praziquantel with the reversal of Symmers’ fibrosis induced by Schistosoma mansoni. Am. J. Trop. Med. Hyg., 45: 360 – 365. DOI: 10.4269/ajtmh.1991.45.36010.4269/ajtmh.1991.45.3601928571Open DOISearch in Google Scholar

Issa, RM. (2007): Schistosoma mansoni: The prophylactic and curative effects of propolis in experimentally-infected mice. Rawal. Med. J., 32: 94 – 98Search in Google Scholar

Kadry, S.M., Mohamed, A.M., Farrag, E.M., Dalia, B., Fayed, D.B. (2013): Influence of some micronutrients and Citharexylum quadrangular extract against liver fibrosis in Schistosoma mansoni infected mice. Afr. J. Pharm. Pharmacol., 7(38): 2628 – 2638. DOI: 10.5897/AJPP12.62010.5897/AJPP12.620Open DOISearch in Google Scholar

Kulisic-Bilusic, T., Schmöllerb, I., Schnäbeleb, K., Siracusac, L., Rubertoc, G. (2012): The anticarcinogenic potential of essential oil and aqueous infusion from caper (Capparis spinosa L.). Food. Chem., 132: 261 – 267. DOI: 10.1016/j.foodchem.2011.10.07410.1016/j.foodchem.2011.10.07426434289Open DOISearch in Google Scholar

Lam, S.K., Han, Q.F. Ng, T.B. (2008): Isolation and characterization of a lectin with potentially exploitable activities from caper (Capparis spinosa). Biosci. Rep. Immed. Pub., 29(5): 293 – 299. DOI: 10.1042/BSR200801110.1042/BSR2008011Open DOISearch in Google Scholar

Liang, Y.S., John, B.I., Boyd, D.A. (1987): Laboratory cultivation of schistosome vector snails and maintenance of schistosome life cycles. In Proceeding of the 1st Sino-American Symposium, 1, pp. 34 – 48Search in Google Scholar

Manikandaselvi, S., Brindha, P. (2014): Chemical standardization studies on Capparis spinosa L. Int. J. Pharm. Pharm. Sci., 6(Suppl. 1): 47 – 54Search in Google Scholar

Manikandaselvi, S., Vadivel, V., Brindha, P. (2016): Review on ethnobotanical studies of nutraceutical plant: Capparis spinosa L. (Caper). Asian J. Pharm. Clin. Res., 9: 123 – 126Search in Google Scholar

Mahmoud, E.A., Elbessoumy, A.A. (2013): Effect of curcumin on hematological, biochemical and antioxidants parameters in Schistosoma mansoni infected mice. Int. J. Sci., 2: 1 – 14Search in Google Scholar

Naik, S.R., Thakare, V.N., Patil, S.R. (2011): Protective effect of curcumin on experimentally induced inflammation, hepatotoxicity and cardiotoxicity in rats: evidence of its antioxidant property. Exp. Toxicol. Pathol., 63: 419 – 431. DOI: 10.1016/j.etp.2010.03.00110.1016/j.etp.2010.03.00120363603Open DOISearch in Google Scholar

Oliveira, S.A., Souza, B.S., Guimaraes-Ferreira, C.A., Barreto, E.S., Souza, S.C., Freitas, L.A., Ribeiro-Dos-Santos, R., Soares, M.B. (2008): Therapy with bone marrow cells reduces liver alterations in mice chronically infected by Schistosoma mansoni. World J. Gastroenterol., 14(38): 5842 – 5850. DOI: 10.3748/wjg.14.584210.3748/wjg.14.5842275189418855983Open DOISearch in Google Scholar

Pellegrino, J., Oliveira, C.A., Faria, J., Cunha, A.S. (1962): New approach to the screening of drugs in experimental Schistosomiasis mansoni in mice. Am. J. Trop. Med. Hyg., 11: 201 – 215. DOI: 10.4269/ajtmh.1962.11.20110.4269/ajtmh.1962.11.20114484966Open DOISearch in Google Scholar

Polyak, S.J., Ferenci, P., Pawlotsky, J-M. (2013): Hepatoprotective and Antiviral Functions of Silymarin Components in HCV Infection. Hepatology, 57: 1262 – 1271. DOI: 10.1002/hep.2617910.1002/hep.26179359465023213025Open DOISearch in Google Scholar

Rabia, I., Nagy, F., Aly, E., Mohamed, A., EL-Assal, F., El-Amir, A. (2010): Effect of treatment with antifibrotic drugs in combination with PZQ in immunized Schistosoma mansoni-infected murine model. J. Amer. Sci., 6: 208 – 216. DOI: 10.7537/marsjas060510.3010.7537/marsjas060510.30Open DOISearch in Google Scholar

Rahmani, R., Mahmoodi, M., Karimi, M., Hoseini; F., Heydari, R., Salehi, M. Yousefi, A. (2013): Effect of hydroalcoholic extract of Capparis spinosa fruit on blood sugar and lipid profile of diabetic and normal rats. ZJRMS, 15(11): 34 – 38Search in Google Scholar

Rose, G. (2013): Benefits of Polyphenols. Retrieved November 19, 2015 from http://www.live-strong.com/article/173125-benefits-of-polyphenols/.Search in Google Scholar

Satyanarayana, T., Devi, K., Mathews, A.A. (2009): Hepatoprotective activity of Capparis sepiaria stem against carbon tetrachloride-induced hepatotoxicity in rats. JPRHC, 1: 34 – 45Search in Google Scholar

Sher, H., Alyemeni, M. (2010): Ethnobotanical and pharmaceutical evaluation of Capparis spinosa L., validity of local folk and Unani system of medicine. J. Med. Plan. Res., 4: 1751 – 1756. DOI: 10.5897/JMPR10.38010.5897/JMPR10.380Open DOISearch in Google Scholar

Sherif, M.M., El-Shiekh, H.H.; Elaasser, M.M., Elbadry, M.A. (2013): In vitro evaluation of antimicrobial and cytotoxic effects of Caper (Capparis spinosa). J. App. Sci. Res., 9(4): 2944 – 2950Search in Google Scholar

Tapas, A.R., Sakarkar, D.M., Kakde, R.B. (2008): Flavonoids as Nu traceuticals: A Review. Trop. J. Pharm. Res. 7: 1089 – 1099. DOI: 10.4314/tjpr.v7i3.1469310.4314/tjpr.v7i3.14693Open DOISearch in Google Scholar

Tlili, N., Elfalleh, W., Saadaoui, E., Khaldi, A., Triki, S., Nasri, N. (2011): The caper (Capparis L.): Ethnopharmacology, phytochemical and pharmacological properties. Fitoterapia. 82 93 – 101. DOI: 10.1016/j.fitote.2010.09.00610.1016/j.fitote.2010.09.00620851750Open DOISearch in Google Scholar

Tesoriere, L., Butera, D., Gentile, C., Livrea, M.A. (2007): Bioactive components of Caper (Capparis spinosa L.) from Sicily and antioxidant effects in a red meat simulated gastric digestion. J. Agric. Food Chem., 55: 8465 – 8471. DOI: 10.1021/jf071411310.1021/jf071411317887802Open DOISearch in Google Scholar

Von Lichtenberg, F.C. (1962): Host response to eggs of Schistosoma mansoni. I. Granuloma formation in the sensitized laboratory mouse. Am. J. Pathol., 41: 711 – 731Search in Google Scholar

Yu, Y., Gao, H., Tang, Z., Song, X., Wu, L. (2006): Several phenolic acids from the fruit of Capparis spinosa. Asian J. Tradit. Med., 1: 3 – 4Search in Google Scholar

Zhou, H., Xie, C., Jian, R., Kang, J., Kang, J., Li, Y., Zhuang, C., Yang, F., Zhang, L., Lai, L., Wu, T. Wu, X. (2011): Biflavonoids from Caper (Capparis spinosa L.) Fruits and Their Effects in Inhibiting NF-kappa B Activation. J. Agric. Food Chem., 59(7): 3060 – 3065. DOI: 10.1021/jf105017j10.1021/jf105017j21381749Open DOISearch in Google Scholar

eISSN:
1336-9083
ISSN:
0440-6605
Language:
English
Publication timeframe:
4 times per year
Journal Subjects:
Life Sciences, Zoology, Ecology, other, Medicine, Clinical Medicine, Microbiology, Virology and Infection Epidemiology