<abstract xmlns="http://www.w3.org/1999/xhtml"><p> The proteolytic activity in washings off the Triaenophorus nodulosus cestode tegument and the ability of the worms to inactivate proteolytic enzymes were studied. It was found that the major proteolytic activity in the washing samples is represented by the easily desorbed fraction most probably characterizing the activity of the host’s enzymes. Serine proteinases are an essential part of these enzymes. It was shown that the worms’ incubation medium and their homogenates can inhibit host proteinases and commercial trypsin samples. Suppressive activity of the incubation medium suggests that the inhibitors are rather spontaneously produced by the worms than induced by the presence of proteinases in the surrounding medium. The inhibitor produced by the cestode is hypothesized to be trypsin-specific.</p></abstract>

The proteolytic activity in washings off the Triaenophorus nodulosus cestode tegument and the ability of the worms to inactivate proteolytic enzymes were studied. It was found that the major proteolytic activity in the washing samples is represented by the easily desorbed fraction most probably characterizing the activity of the host’s enzymes. Serine proteinases are an essential part of these enzymes. It was shown that the worms’ incubation medium and their homogenates can inhibit host proteinases and commercial trypsin samples. Suppressive activity of the incubation medium suggests that the inhibitors are rather spontaneously produced by the worms than induced by the presence of proteinases in the surrounding medium. The inhibitor produced by the cestode is hypothesized to be trypsin-specific.

Adsorption and inactivation of proteolytic enzymes by Triaenophorus nodulosus (Cestoda)

I.D. Papanin Institute for Biology of Inland Waters, Russian Academy of Sciences, Borok, Nekouzskii raion, Yaroslavskaya oblast, 152742,

Helminthologia

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

The proteolytic activity in washings off the Triaenophorus nodulosus cestode tegument and the ability of the worms to inactivate proteolytic enzymes were...

Adsorption and inactivation of proteolytic enzymes by Triaenophorus nodulosus (Cestoda)

Article Category: Research Article

Published Online: Feb 09, 2017

Page range: 3 - 10

Received: Sep 20, 2016

Accepted: Dec 15, 2016

DOI: https://doi.org/10.1515/helm-2017-0001

Keywords
fish, Cestodes, Triaenophorus nodulosus, digestive enzymes, proteolytic activity, proteinase inhibitors

© 2017

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Adsorption and inactivation of proteolytic enzymes by Triaenophorus nodulosus (Cestoda)

Article Category: Research Article

Published Online: Feb 09, 2017

Page range: 3 - 10

Received: Sep 20, 2016

Accepted: Dec 15, 2016

DOI: https://doi.org/10.1515/helm-2017-0001

Keywordsfish, Cestodes, Triaenophorus nodulosus, digestive enzymes, proteolytic activity, proteinase inhibitors

© 2017

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Keywords
fish, Cestodes, Triaenophorus nodulosus, digestive enzymes, proteolytic activity, proteinase inhibitors