<abstract xmlns="http://www.w3.org/1999/xhtml"><p> A 31-year-old lady, diagnosed to have premature ovarian failure in the gynecology clinic, was referred for endocrine assessment because of an abnormal thyroid function test. Clinical examination revealed hypotension, and fungal skin infection under her atrophic breasts. Thyroid stimulating hormone (TSH) level was very high. Assessment of the suprarenal function revealed evidence of Addison’s disease. Polyglandular autoimmune dysfunction was diagnosed. She was treated with prednisone, fludrocortisone, and levothyroxine with significant improvement of her general condition and blood pressure.</p></abstract>

A 31-year-old lady, diagnosed to have premature ovarian failure in the gynecology clinic, was referred for endocrine assessment because of an abnormal thyroid function test. Clinical examination revealed hypotension, and fungal skin infection under her atrophic breasts. Thyroid stimulating hormone (TSH) level was very high. Assessment of the suprarenal function revealed evidence of Addison’s disease. Polyglandular autoimmune dysfunction was diagnosed. She was treated with prednisone, fludrocortisone, and levothyroxine with significant improvement of her general condition and blood pressure.

Premature ovarian failure could be an alarming sign of polyglandular autoimmune dysfunction

Endocrine Regulations

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A 31-year-old lady, diagnosed to have premature ovarian failure in the gynecology clinic, was referred for endocrine assessment because of an abnormal thyroid...

Premature ovarian failure could be an alarming sign of polyglandular autoimmune dysfunction

Published Online: Jun 13, 2017

Page range: 114 - 116

DOI: https://doi.org/10.1515/enr-2017-0011

Keywords
ovarian failure, polyglandular autoimmune syndrome, hypothyroidism, adrenal failure

© 2017

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Premature ovarian failure could be an alarming sign of polyglandular autoimmune dysfunction

Published Online: Jun 13, 2017

Page range: 114 - 116

DOI: https://doi.org/10.1515/enr-2017-0011

Keywordsovarian failure, polyglandular autoimmune syndrome, hypothyroidism, adrenal failure

© 2017

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Keywords
ovarian failure, polyglandular autoimmune syndrome, hypothyroidism, adrenal failure