<abstract xmlns="http://www.w3.org/1999/xhtml"><p> Littoral cell angioma is a rare primary, vascular tumor thought to originate from the endothelial cells lining the sinuses of the splenic red pulp (the “littoral cells”). It is a benign, usually asymptomatic lesion diagnosed incidentally. Ultrasound and tomography appearance is not characteristic and histopathological examination is required. This work provides a case-study of littoral cell angioma which was seen in a 55-year-old female who complained of non-specific upper abdominal pain. Computed tomography revealed multiple hypo-attenuated splenic lesions suggestive for metastasis. A splenectomy was performed and routine microscopic examination supported by immunohistochemistry reactions with CD68, CD34 and CD31 showed littoral cell angioma.</p></abstract>

Littoral cell angioma is a rare primary, vascular tumor thought to originate from the endothelial cells lining the sinuses of the splenic red pulp (the “littoral cells”). It is a benign, usually asymptomatic lesion diagnosed incidentally. Ultrasound and tomography appearance is not characteristic and histopathological examination is required. This work provides a case-study of littoral cell angioma which was seen in a 55-year-old female who complained of non-specific upper abdominal pain. Computed tomography revealed multiple hypo-attenuated splenic lesions suggestive for metastasis. A splenectomy was performed and routine microscopic examination supported by immunohistochemistry reactions with CD68, CD34 and CD31 showed littoral cell angioma.

Littoral cell angioma mimicking metastatic tumors

Chair and Department of Clinical Pathology, Medical University of Lublin, 8b Jaczewskiego, 20-090 Lublin, Poland

Chair and Department of General and Transplant Surgery and Nutritional Treatment, Medical University of Lublin, 8 Jaczewskiego, 20-954 Lublin, Poland

Chair and Department of Human Anatomy, Medical University of Lublin, 4 Jaczewskiego, 20-090 Lublin, Poland

1st Department of Radiology, Medical University of Lublin, 8 Jaczewskiego, 20-954 Lublin, Poland

Current Issues in Pharmacy and Medical Sciences

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

{"article-title":"Littoral cell angioma mimicking metastatic tumors"}

Littoral cell angioma is a rare primary, vascular tumor thought to originate from the endothelial cells lining the sinuses of the splenic red pulp (the...

Littoral cell angioma mimicking metastatic tumors

Published Online: Dec 30, 2015

Page range: 247 - 249

Received: Oct 05, 2015

Accepted: Nov 03, 2015

DOI: https://doi.org/10.1515/cipms-2015-0081

Keywords
littoral cell angioma, spleen, splenic tumor, splenic metastasis

© 2016

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Littoral cell angioma mimicking metastatic tumors

Published Online: Dec 30, 2015

Page range: 247 - 249

Received: Oct 05, 2015

Accepted: Nov 03, 2015

DOI: https://doi.org/10.1515/cipms-2015-0081

Keywordslittoral cell angioma, spleen, splenic tumor, splenic metastasis

© 2016

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Keywords
littoral cell angioma, spleen, splenic tumor, splenic metastasis