<abstract xmlns="http://www.w3.org/1999/xhtml"><p>This paper provides a description of an alternative, novel and commercially viable process which has been developed for the preparation of Azilsartan, a pro-drug of Azilsartan medoxomil, an angiotensin II receptor blocker. The present work also provides a primary account of the synthesis and characterization of the novel intermediates (6, 7 &amp; 10) of Azilsartan, with their spectral data.</p></abstract>

This paper provides a description of an alternative, novel and commercially viable process which has been developed for the preparation of Azilsartan, a pro-drug of Azilsartan medoxomil, an angiotensin II receptor blocker. The present work also provides a primary account of the synthesis and characterization of the novel intermediates (6, 7 & 10) of Azilsartan, with their spectral data.

An alternative synthesis of Azilsartan: an angiotensin II receptor blocker

Chemical Research and Development Department, Aurobindo Pharma Ltd, Survey No: 71&72, Indrakaran Village, Sangareddy Mandal, Medak district, Hyderabad – 502329, Andhra Pradesh, India

Department of Engineering Chemistry, A. U. College of Engineering (A), Andhra University, Visakhapatnam – 530003, Andhra Pradesh, India

Current Issues in Pharmacy and Medical Sciences

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"An alternative synthesis of Azilsartan: an angiotensin II receptor blocker"}

This paper provides a description of an alternative, novel and commercially viable process which has been developed for the preparation of Azilsartan, a...

An alternative synthesis of Azilsartan: an angiotensin II receptor blocker

Published Online: Jul 16, 2015

Page range: 72 - 76

Received: Nov 14, 2014

Accepted: Mar 27, 2015

DOI: https://doi.org/10.1515/cipms-2015-0047

Keywords
Azilsartan, novel intermediates, synthesis and characterization

© 2015

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

An alternative synthesis of Azilsartan: an angiotensin II receptor blocker

Published Online: Jul 16, 2015

Page range: 72 - 76

Received: Nov 14, 2014

Accepted: Mar 27, 2015

DOI: https://doi.org/10.1515/cipms-2015-0047

KeywordsAzilsartan, novel intermediates, synthesis and characterization

© 2015

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
Azilsartan, novel intermediates, synthesis and characterization