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<p>A detailed study on histopathological lesions induced by two <italic>C. psittaci</italic> outer membrane protein A (<italic>ompA</italic>) genotype B strains (10/423 and 10/525) and one genotype D strain (10/298) in experimentally infected (aerosol) specific pathogen free (SPF) chickens was performed. The strains were derived from Belgian and French commercially raised broilers with pneumonia. Both genotype B and D strains induced conjunctivitis, rhinitis, sinusitis, tracheitis, bronchitis, pneumonitis, airsacculitis, splenitis, hepatitis, nephritis, and enteritis in sequentially (days 2 to 34 post infection) euthanized chickens. Inflammation of the ovaries was only observed in genotype D infected chickens. Overall, the genotype D strain caused more severe gross and histopathological lesions and mortality (54.5%) early upon infection. The genotype D strain seemed to replicate faster as severity of the lesions increased more quickly. <italic>C. psittaci</italic> is a primary pathogen in chickens, and efficient monitoring and control of this emerging zoonotic pathogen is urgently needed.</p>
</abstract>

A detailed study on histopathological lesions induced by two C. psittaci outer membrane protein A (ompA) genotype B strains (10/423 and 10/525) and one genotype D strain (10/298) in experimentally infected (aerosol) specific pathogen free (SPF) chickens was performed. The strains were derived from Belgian and French commercially raised broilers with pneumonia. Both genotype B and D strains induced conjunctivitis, rhinitis, sinusitis, tracheitis, bronchitis, pneumonitis, airsacculitis, splenitis, hepatitis, nephritis, and enteritis in sequentially (days 2 to 34 post infection) euthanized chickens. Inflammation of the ovaries was only observed in genotype D infected chickens. Overall, the genotype D strain caused more severe gross and histopathological lesions and mortality (54.5%) early upon infection. The genotype D strain seemed to replicate faster as severity of the lesions increased more quickly. C. psittaci is a primary pathogen in chickens, and efficient monitoring and control of this emerging zoonotic pathogen is urgently needed.

<italic>Chlamydia Psittaci</italic> Strains from Broiler Chickens Induce Histopathological Lesions and Mortality in SPF Chickens

Department of Molecular Biotechnology, Faculty of Bioscience Engineering

Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine

Journal of Veterinary Research

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

 Strains from Broiler Chickens Induce Histopathological Lesions and Mortality in SPF Chickens

A detailed study on histopathological lesions induced by two C. psittaci outer membrane protein A (ompA) genotype B strains (10/423 and 10/525) and one...

Chlamydia Psittaci Strains from Broiler Chickens Induce Histopathological Lesions and Mortality in SPF Chickens

Published Online: Apr 01, 2015

Page range: 43 - 50

Received: Jun 26, 2014

Accepted: Jan 14, 2015

DOI: https://doi.org/10.1515/bvip-2015-0007

© 2015 National Veterinary Research Institute in Pulawy

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.