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Zimmet P, Alberti KG, Shaw J. Global and societal implications of the diabetes epidemic. Nature. 2001; 414 (6865): 782-787.ZimmetPAlbertiKGShawJ.Global and societal implications of the diabetes epidemic20014146865782787Search in Google Scholar
Alberti G, Zimmet P, Shaw J, Bloomgarden Z, Kaufman F, Silink M. Type 2 diabetes in the young: The evolving epidemic: The International Diabetes Federation Consensus Workshop. Diabetes Care. 2004; 27(7): 1798-1811.AlbertiGZimmetPShawJBloomgardenZKaufmanFSilinkM.Type 2 diabetes in the young: The evolving epidemic: The International Diabetes Federation Consensus Workshop200427717981811Search in Google Scholar
Blaha MJ, Bansal S, Rouf R, Golden SH, Blumenthal RS, Defilippis AP. A practical “ABCDE” approach to the metabolic syndrome. Mayo Clin Proc. 2008; 83(8): 932-941.BlahaMJBansalSRoufRGoldenSHBlumenthalRSDefilippisAP.A practical “ABCDE” approach to the metabolic syndrome2008838932941Search in Google Scholar
Chen J, Muntner P, Hamm LL, Jones DW, Batuman V, Fonseca V, et al. The metabolic syndrome and chronic kidney disease in U.S. adults. Ann Intern Med. 2004; 140(3): 167-174.ChenJMuntnerPHammLLJonesDWBatumanVFonsecaVThe metabolic syndrome and chronic kidney disease in U.S. adults20041403167174Search in Google Scholar
Fujita T. Aldosterone in salt-sensitive hypertension and metabolic syndrome. J Mol Med. 2008; 86(6): 729-734.FujitaT.Aldosterone in salt-sensitive hypertension and metabolic syndrome2008866729734Search in Google Scholar
Ren J, Pulakat L, Whaley-Connell A, Sowers JR. Mitochondrial biogenesis in the metabolic syndrome and cardiovascular disease. J Mol Med. 2010; 88(10): 993-1001.RenJPulakatLWhaley-ConnellASowersJR.Mitochondrial biogenesis in the metabolic syndrome and cardiovascular disease201088109931001Search in Google Scholar
Owen JG, Reisin E. Anti-hypertensive drug treatment of patients with and the metabolic syndrome and obesity: A review of evidence, meta-analysis, post hoc and guidelines publications. Curr Hypertens Rep. 2015; 17(6): 1-10.OwenJGReisinE.Anti-hypertensive drug treatment of patients with and the metabolic syndrome and obesity: A review of evidence meta-analysis, post hoc and guidelines publications2015176110Search in Google Scholar
O’Neill S, O’Driscoll L. Metabolic syndrome: A closer look at the growing epidemic and its associated pathologies. Obes Rev. 2015; 16(1): 1-12.O’NeillSO’DriscollL.Metabolic syndrome: A closer look at the growing epidemic and its associated pathologies2015161112Search in Google Scholar
Franchini M, Montagna M. Low-density lipoprotein receptor-related protein 1: New functions for an old molecule. Clin Chem Lab Med. 2011; 49(6): 967-970.FranchiniMMontagnaM.Low-density lipoprotein receptor-related protein 1: New functions for an old molecule2011496967970Search in Google Scholar
Alberti KG, Zimmet P, Shaw J. Metabolic syndrome – A new world-wide definition. A consensus statement from the International Diabetes Federation. Diabet Med. 2006; 23(5): 469-480.AlbertiKGZimmetPShawJ.Metabolic syndrome – A new world-wide definition. A consensus statement from the International Diabetes Federation2006235469480Search in Google Scholar
Evans A, Talonen H, Hense HW, Ferrario M, Sans S, Kuulasmaa K. Trends in coronary risk factors in the WHO MONICA Project. Int J Epidemiol. 2001; 30(Suppl 1):s35-s40.EvansATalonenHHenseHWFerrarioMSansSKuulasmaaK.Trends in coronary risk factors in the WHO MONICA Project2001301s35s40Search in Google Scholar
Liu Q, Trotter J, Zhang J, Peters MM, Cheng H, Bao J, et al. Neuronal LRP1 knockout in adult mice leads to impaired brain lipid metabolism and progressive, age-dependent synapse loss and neurodegeneration. J Neurosci. 2010; 30(50): 17068-17078.LiuQTrotterJZhangJPetersMMChengHBaoJNeuronal LRP1 knockout in adult mice leads to impaired brain lipid metabolism and progressive, age-dependent synapse loss and neurodegeneration201030501706817078Search in Google Scholar
Christoforidis M, Schober R, Krohn K. Geneticmorphologic association study: Association between the low density lipoprotein-receptor related protein (LRP1) and cerebral amyloid angiopathy. Neuropathol Appl Neurobiol. 2005; 31(1): 11-19.ChristoforidisMSchoberRKrohnK.Geneticmorphologic association study: Association between the low density lipoprotein-receptor related protein (LRP1) and cerebral amyloid angiopathy20053111119Search in Google Scholar
Vormittag R, Bencur P, Ay C, Tengler T, Vukovich T, Quehenberger P, et al. Low-density lipoprotein receptor-related protein 1 polymorphism 663 C>T affects clotting factor VIII activity and increases the risk of venous thromboembolism. J Thromb Haemost. 2007; 5(3): 497-502.VormittagRBencurPAyCTenglerTVukovichTQuehenbergerPLow-density lipoprotein receptor-related protein 1 polymorphism 663 C>T affects clotting factor VIII activity and increases the risk of venous thromboembolism200753497502Search in Google Scholar
Masson O, Chavey C, Dray C, Meulle A, Daviaud D, Quilliot D, et al. LRP1 receptor controls adipogenesis and is up-regulated in human and mouse obese adipose tissue. PLoS One. 2009; 4(10): e7422. 10.1371/journal.pone.0007422.MassonOChaveyCDrayCMeulleADaviaudDQuilliotDLRP1 receptor controls adipogenesis and is up-regulated in human and mouse obese adipose tissue2009410e742210.1371/journal.pone.0007422Open DOISearch in Google Scholar
Liu Q, Zhang J, Zerbinatti C, Zhan Y, Kolber BJ, Herz J, et al. Lipoprotein receptor LRP1 regulates leptin signaling and energy homeostasis in the adult central nervous system. PLoS Biol. 2011; 9(1): 1-9.LiuQZhangJZerbinattiCZhanYKolberBJHerzJLipoprotein receptor LRP1 regulates leptin signaling and energy homeostasis in the adult central nervous system20119119Search in Google Scholar
Niemeier A, Kassem M, Toedter K, Wendt D, Ruether W, Beisiegel U, et al. Expression of LRP1 by human osteoblasts: A mechanism for the delivery of lipo-proteins and vitamin K1 to bone. J Bone Miner Res. 2005; 20(2): 283-293.NiemeierAKassemMToedterKWendtDRuetherWBeisiegelUExpression of LRP1 by human osteoblasts: A mechanism for the delivery of lipo-proteins and vitamin K1 to bone2005202283293Search in Google Scholar
Meng H, Chen G, Zhang X, Wang Z, Thomas D, Giordano T, et al. Stromal LRP1 in lung adenocarcinoma predicts clinical outcome. Clin Cancer Res. 2011; 17(8): 2426-2433.MengHChenGZhangXWangZThomasDGiordanoTStromal LRP1 in lung adenocarcinoma predicts clinical outcome201117824262433Search in Google Scholar
Neels JG, Bovenschen N, van Zonneveld AJ, Lenting PJ. Interaction between factor VIII and LDL receptorrelated protein. Modulation of coagulation? Trends Cardiovasc Med. 2000; 11(1): 251-257.NeelsJGBovenschenNvan ZonneveldAJLentingPJ.Interaction between factor VIII and LDL receptorrelated protein. Modulation of coagulation?2000111251257Search in Google Scholar
Kang DE, Saitoh T, Chen X, Xia Y, Masliah E, Hansen LA, et al. Genetic association of the low-density lipoprotein receptor-related protein gene (LRP), an apolipoprotein E receptor, with late-onset Alzheimer’s disease. Neurology. 1997; 49(1): 56-61.KangDESaitohTChenXXiaYMasliahEHansenLAGenetic association of the low-density lipoprotein receptor-related protein gene (LRP), an apolipoprotein E, receptor with late-onset Alzheimer’s disease19974915661Search in Google Scholar
Clemente-Postigo M, Queipo-Ortuno MI, Fernandez-Garcia D, Gomez-Huelgas R, Tinahones FJ, Cardona F. Adipose tissue gene expression of factors related to lipid processing in obesity. PLoS One. 2011; 6(9): e24783. 10.1371/journal.pone.0024783.Clemente-PostigoMQueipo-OrtunoMIFernandez-GarciaDGomez-HuelgasRTinahonesFJCardonaF.Adipose tissue gene expression of factors related to lipid processing in obesity201169e2478310.1371/journal.pone.0024783Open DOISearch in Google Scholar
Hofmann SM, Zhou L, Perez-Tilve D, Greer T, Grant E, Wancata L, et al. Adipocyte LDL receptor-related protein-1 expression modulates postprandial lipid transport and glucose homeostasis in mice. J Clin Invest. 2007; 117(11): 3271-3282.HofmannSMZhouLPerez-TilveDGreerTGrantEWancataLAdipocyte LDL receptor-related protein-1 expression modulates postprandial lipid transport and glucose homeostasis in mice20071171132713282Search in Google Scholar
Hatanaka Y, Kamino K, Fukuo K, Mitsuda N, Nishiwaki-Ueda Y, Sato N, et al. Low density lipoprotein receptor-related protein gene polymorphisms and risk for late-onset Alzheimer’s disease in a Japanese population. Clin Genet. 2000; 58(4): 319-323.HatanakaYKaminoKFukuoKMitsudaNNishiwaki-UedaYSatoNLow density lipoprotein receptor-related protein gene polymorphisms and risk for late-onset Alzheimer’s disease in a Japanese population2000584319323Search in Google Scholar
A consensus statement from the International Diabetes Federation. Diabet Med. 2006; 23(4): 469-480.A consensus statement from the International Diabetes Federation2006234469480Search in Google Scholar
Kassi E, Pervanidou P, Chrousos G. Metabolic syndrome: Definitions and controversies. BMC Med. 2011; 9: 48. 10.1186/1741-7015-9-48.KassiEPervanidouPChrousosG.Metabolic syndrome: Definitions and controversies201194810.1186/1741-7015-9-48Open DOISearch in Google Scholar
Friedewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low-density lipoprotein cholesterol in plasma without use of preparative centrifuge. Clin Chem. 1972; 18(6): 499-502.FriedewaldWTLevyRIFredricksonDS.Estimation of the concentration of low-density lipoprotein cholesterol in plasma without use of preparative centrifuge1972186499502Search in Google Scholar
Sambrook JF, Russel DW. Molecular Cloning: A Laboratory Manual, 3rd ed. Cold Spring Harbor, NY, USA: Cold Spring Harbor Laboratory Press, 2001.SambrookJFRusselDW.3rdCold Spring Harbor NY, USACold Spring Harbor Laboratory Press2001Search in Google Scholar
StatSoft, Inc. STATISTICA (data analysis software system), version 10, 2011. www.statsoft.comSTATISTICA (data analysis software system)102011www.statsoft.comSearch in Google Scholar
http://www.ensembl.org/Homo_sapiens/Variation/Population?db=core;r=12:57540765-57541765;v=rs2306692;vdb=variation;vf=1890007#102187_tablePanel.Search in Google Scholar
Panza F, D’Introno A, Colacicco AM, Capurso C, Basile AM, Capurso S, et al. Regional European differences in allele and genotype frequencies of low density lipoprotein receptor-related protein 1 polymorphism in Alzheimers disease. Am J Med Genet Part B Neuropsychiatr Genet. 2004; 126B(1): 69-73.PanzaFD’IntronoAColaciccoAMCapursoCBasileAMCapursoSRegional European differences in allele and genotype frequencies of low density lipoprotein receptor-related protein 1 polymorphism in Alzheimers disease2004126B16973Search in Google Scholar
Beneš P, Jurajda M, Žaloudík J, Izakovičová-Hollá L, Vácha J. C766T low-density lipoprotein receptorrelated protein 1 (LRP1) gene polymorphism and susceptibility to breast cancer. Breast Cancer Res. 2003; 5(3):R77-R81.BenešPJurajdaMŽaloudíkJIzakovičová-HolláLVáchaJ.C766T low-density lipoprotein receptorrelated protein 1 (LRP1) gene polymorphism and susceptibility to breast cancer200353R77R81Search in Google Scholar
Vučinić N, Djan I, Stokić E, Božin B, Obreht D, Stankov K, et al. Different associations of apoE gene polymorphism with metabolic syndrome in the Vojvodina Province (Serbia). Molec Biol Rep. 2014; 41(8): 5221-5227.VučinićNDjanIStokićEBožinBObrehtDStankovKDifferent associations of apoE gene polymorphism with metabolic syndrome in the Vojvodina Province (Serbia)201441852215227Search in Google Scholar