<abstract xmlns="http://www.w3.org/1999/xhtml"><p> Sixteen (3,4-dichlorophenyl)-3-(substituted phenyl)bicyclo[2.2.1]hept-5-ene-2-yl) methanone derivatives have been synthesized by an aqueous phase fly-ash catalyzed [4+2] cycloaddition Diels-Alder reaction of cyclopentadiene and 3,4-dichloro phenyl chalcones. The yields of the methanones were greater than 60%. The synthesized methanones were characterized by their physical constants and spectral data. The antimicrobial and antioxidant activities of the synthesized methanones were evaluated using a variety of bacterial and fungal species and DPPH radical scavenging methods.</p></abstract>

Sixteen (3,4-dichlorophenyl)-3-(substituted phenyl)bicyclo[2.2.1]hept-5-ene-2-yl) methanone derivatives have been synthesized by an aqueous phase fly-ash catalyzed [4+2] cycloaddition Diels-Alder reaction of cyclopentadiene and 3,4-dichloro phenyl chalcones. The yields of the methanones were greater than 60%. The synthesized methanones were characterized by their physical constants and spectral data. The antimicrobial and antioxidant activities of the synthesized methanones were evaluated using a variety of bacterial and fungal species and DPPH radical scavenging methods.

Synthesis, characterization and evaluation of biological activities of some 2,3-diaryl bicyclo methanones

thirunarayanan.g.10313@annamalaiuniversity.ac.in

Department of Chemistry, Annamalai University, Annamalainagar 608 002, India

Ovidius University Annals of Chemistry

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Sixteen (3,4-dichlorophenyl)-3-(substituted phenyl)bicyclo[2.2.1]hept-5-ene-2-yl) methanone derivatives have been synthesized by an aqueous phase fly-ash...

Synthesis, characterization and evaluation of biological activities of some 2,3-diaryl bicyclo methanones

Published Online: Jun 28, 2016

Page range: 36 - 43

Received: Jan 24, 2016

Accepted: Mar 07, 2016

DOI: https://doi.org/10.1515/auoc-2016-0003

© Ovidius University Press

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.